ENSG00000111786

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000229390 ENSG00000111786 No_inf pgKDN_inf SRSF9 protein_coding protein_coding 163.3919 139.5835 178.6871 2.653026 3.3997 0.3562845 138.834588 105.89585 158.767046 2.7096118 2.6215177 0.5842201 0.84350833 0.758525 0.888875 0.130350 9.930883e-07 9.930883e-07 FALSE TRUE
ENST00000546942 ENSG00000111786 No_inf pgKDN_inf SRSF9 protein_coding retained_intron 163.3919 139.5835 178.6871 2.653026 3.3997 0.3562845 8.607625 10.87980 7.240430 0.3765866 1.4299234 -0.5868383 0.05435833 0.077925 0.040150 -0.037775 2.922525e-01 9.930883e-07 FALSE FALSE
ENST00000548792 ENSG00000111786 No_inf pgKDN_inf SRSF9 protein_coding retained_intron 163.3919 139.5835 178.6871 2.653026 3.3997 0.3562845 11.341374 14.74189 9.326793 1.4641755 0.8732627 -0.6599011 0.07209167 0.106175 0.052025 -0.054150 1.177095e-01 9.930883e-07 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111786 E001 0.000000       12 120461672 120461692 21 -      
ENSG00000111786 E002 0.000000       12 120461693 120461710 18 -      
ENSG00000111786 E003 0.000000       12 120461711 120461761 51 -      
ENSG00000111786 E004 0.000000       12 120461762 120462162 401 -      
ENSG00000111786 E005 0.000000       12 120462163 120463396 1234 -      
ENSG00000111786 E006 32.429434 0.0017215699 3.908240e-01 0.6761265674 12 120463950 120463977 28 - 1.544 1.501 -0.146
ENSG00000111786 E007 159.563741 0.0001310022 5.184953e-01 0.7735140232 12 120463978 120464122 145 - 2.210 2.200 -0.034
ENSG00000111786 E008 36.813356 0.0059953809 3.771375e-06 0.0001471819 12 120464123 120464732 610 - 1.428 1.696 0.916
ENSG00000111786 E009 7.576762 0.0042295117 5.178508e-04 0.0089781909 12 120464733 120464822 90 - 0.724 1.083 1.369
ENSG00000111786 E010 9.536099 0.0019235791 1.129990e-03 0.0164582463 12 120464823 120464943 121 - 0.852 1.153 1.114
ENSG00000111786 E011 26.936544 0.0007085535 6.186836e-06 0.0002256125 12 120465139 120465626 488 - 1.301 1.562 0.899
ENSG00000111786 E012 129.542673 0.0002021898 1.629202e-02 0.1108747444 12 120465627 120465755 129 - 2.141 2.086 -0.182
ENSG00000111786 E013 54.512439 0.0003305570 3.798151e-01 0.6664372141 12 120465756 120465787 32 - 1.759 1.728 -0.106
ENSG00000111786 E014 128.326470 0.0001547845 1.515260e-03 0.0206634698 12 120469422 120469748 327 - 2.145 2.072 -0.244

Help

Please Click HERE to learn more details about the results from DEXseq.