ENSG00000111880

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369485 ENSG00000111880 No_inf pgKDN_inf RNGTT protein_coding protein_coding 16.10631 9.507068 19.52681 0.3449148 1.577598 1.037606 3.139965 3.1097780 4.498891 0.3213197 0.8132619 0.5313293 0.22354167 0.328900 0.247375 -0.081525 0.81285191 0.04584938 FALSE TRUE
ENST00000538899 ENSG00000111880 No_inf pgKDN_inf RNGTT protein_coding protein_coding 16.10631 9.507068 19.52681 0.3449148 1.577598 1.037606 2.512538 0.0000000 4.074671 0.0000000 1.4683126 8.6740760 0.12331667 0.000000 0.193400 0.193400 0.04584938 0.04584938 FALSE TRUE
MSTRG.24998.2 ENSG00000111880 No_inf pgKDN_inf RNGTT protein_coding   16.10631 9.507068 19.52681 0.3449148 1.577598 1.037606 9.208853 6.1549787 10.461479 0.4068944 0.9880881 0.7642974 0.58342500 0.645675 0.533775 -0.111900 0.61768702 0.04584938 FALSE TRUE
MSTRG.24998.4 ENSG00000111880 No_inf pgKDN_inf RNGTT protein_coding   16.10631 9.507068 19.52681 0.3449148 1.577598 1.037606 1.040008 0.1192417 0.000000 0.1192417 0.0000000 -3.6920001 0.05675833 0.011975 0.000000 -0.011975 0.67000556 0.04584938 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000111880 E001 1.224346 0.010391353 4.403417e-01 0.716077119 6 88609897 88610287 391 - 0.285 0.417 0.800
ENSG00000111880 E002 172.442413 0.004848948 4.680617e-05 0.001263485 6 88610288 88612718 2431 - 2.183 2.289 0.356
ENSG00000111880 E003 9.611825 0.008757108 6.473524e-01 0.850966522 6 88612719 88612882 164 - 0.988 1.054 0.245
ENSG00000111880 E004 10.032348 0.001521247 2.131132e-01 0.498358828 6 88614272 88614395 124 - 1.063 0.973 -0.333
ENSG00000111880 E005 0.126507 0.012440959 3.200062e-01   6 88635720 88635779 60 - 0.000 0.122 9.834
ENSG00000111880 E006 0.000000       6 88677994 88678352 359 -      
ENSG00000111880 E007 6.259715 0.005932219 1.046353e-01 0.338110413 6 88678353 88678419 67 - 0.906 0.742 -0.641
ENSG00000111880 E008 0.000000       6 88769770 88769773 4 -      
ENSG00000111880 E009 7.727764 0.002016772 2.693907e-01 0.562982710 6 88769774 88769874 101 - 0.962 0.873 -0.338
ENSG00000111880 E010 7.764223 0.003079730 9.530997e-01 0.988433606 6 88801564 88801632 69 - 0.925 0.942 0.063
ENSG00000111880 E011 13.793959 0.001069878 4.138366e-01 0.694349387 6 88844357 88844521 165 - 1.174 1.133 -0.144
ENSG00000111880 E012 7.830481 0.001818927 8.379296e-02 0.298618319 6 88849755 88849826 72 - 0.988 0.833 -0.585
ENSG00000111880 E013 10.010148 0.001450446 8.575259e-02 0.303177230 6 88853629 88853764 136 - 1.077 0.942 -0.498
ENSG00000111880 E014 8.361345 0.001895790 5.977866e-01 0.823525496 6 88890495 88890596 102 - 0.971 0.942 -0.107
ENSG00000111880 E015 9.351365 0.001559772 9.709450e-01 0.994298137 6 88891806 88891915 110 - 0.996 1.016 0.073
ENSG00000111880 E016 12.205849 0.002153486 1.328666e-01 0.387042516 6 88904715 88904955 241 - 1.146 1.042 -0.375
ENSG00000111880 E017 4.678173 0.187899400 1.014943e-01 0.332651909 6 88906365 88906440 76 - 0.817 0.592 -0.937
ENSG00000111880 E018 4.569344 0.004371210 1.353320e-01 0.391012898 6 88928985 88929073 89 - 0.792 0.626 -0.686
ENSG00000111880 E019 5.548317 0.003483792 2.973244e-01 0.590466754 6 88929164 88929267 104 - 0.841 0.742 -0.393
ENSG00000111880 E020 5.996039 0.021746317 6.116114e-02 0.248374733 6 88941071 88941180 110 - 0.906 0.688 -0.863
ENSG00000111880 E021 7.006286 0.010425258 3.043486e-01 0.597768241 6 88963346 88963618 273 - 0.925 0.833 -0.352

Help

Please Click HERE to learn more details about the results from DEXseq.