ENSG00000112081

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000339436 ENSG00000112081 No_inf pgKDN_inf SRSF3 protein_coding retained_intron 195.6222 151.9573 218.0342 3.832368 5.564961 0.5208603 33.52771 35.06943 29.71667 0.4415719 0.5618432 -0.2388670 0.17751667 0.23125 0.136425 -0.094825 0.00507015 0.00507015 FALSE FALSE
ENST00000373715 ENSG00000112081 No_inf pgKDN_inf SRSF3 protein_coding protein_coding 195.6222 151.9573 218.0342 3.832368 5.564961 0.5208603 45.49364 35.96712 51.88296 1.1321791 2.7959707 0.5284592 0.23339167 0.23705 0.238375 0.001325 1.00000000 0.00507015 FALSE TRUE
ENST00000613941 ENSG00000112081 No_inf pgKDN_inf SRSF3 protein_coding nonsense_mediated_decay 195.6222 151.9573 218.0342 3.832368 5.564961 0.5208603 17.84381 17.88604 19.31867 1.6159063 2.0611673 0.1111023 0.09489167 0.11785 0.089200 -0.028650 0.71995726 0.00507015 FALSE TRUE
ENST00000620242 ENSG00000112081 No_inf pgKDN_inf SRSF3 protein_coding retained_intron 195.6222 151.9573 218.0342 3.832368 5.564961 0.5208603 85.20424 49.39282 102.12434 4.0949554 6.3125699 1.0478026 0.42276667 0.32375 0.467225 0.143475 0.01134095 0.00507015   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112081 E001 0.1176306 1.173292e-02 6.036771e-01   6 36594353 36594361 9 + 0.090 0.000 -8.707
ENSG00000112081 E002 0.8546716 1.904538e-01 8.769054e-01 9.582425e-01 6 36594362 36594366 5 + 0.284 0.250 -0.244
ENSG00000112081 E003 0.9815255 2.049918e-01 8.640378e-01 9.529317e-01 6 36594367 36594367 1 + 0.284 0.309 0.171
ENSG00000112081 E004 31.0882467 4.883148e-03 6.247876e-01 8.385803e-01 6 36594368 36594390 23 + 1.491 1.521 0.103
ENSG00000112081 E005 144.6368061 1.633109e-04 3.651099e-02 1.838023e-01 6 36594391 36594481 91 + 2.187 2.136 -0.171
ENSG00000112081 E006 0.2452102 1.639861e-02 9.280454e-01   6 36594592 36594755 164 + 0.090 0.100 0.172
ENSG00000112081 E007 320.0144950 7.599933e-05 2.513026e-04 5.046074e-03 6 36596761 36596968 208 + 2.534 2.476 -0.192
ENSG00000112081 E008 1.0085620 8.495180e-02 2.712342e-02 1.530844e-01 6 36596969 36597189 221 + 0.090 0.450 2.979
ENSG00000112081 E009 0.7433408 1.403161e-02 3.392406e-01 6.309267e-01 6 36598429 36598526 98 + 0.165 0.309 1.172
ENSG00000112081 E010 254.5037287 1.080615e-04 7.377539e-03 6.544411e-02 6 36598849 36598983 135 + 2.430 2.382 -0.160
ENSG00000112081 E011 42.3086165 3.388770e-04 8.585473e-04 1.333666e-02 6 36599438 36599820 383 + 1.554 1.709 0.526
ENSG00000112081 E012 131.3479775 1.364745e-04 4.825095e-20 1.304804e-17 6 36599821 36600276 456 + 1.987 2.229 0.811
ENSG00000112081 E013 29.1217401 1.678821e-02 3.976544e-03 4.225195e-02 6 36600277 36600402 126 + 1.356 1.578 0.766
ENSG00000112081 E014 101.8921602 1.917020e-04 8.922920e-11 8.995304e-09 6 36600403 36601151 749 + 1.906 2.101 0.654
ENSG00000112081 E015 113.9082320 2.069096e-04 4.299823e-03 4.463631e-02 6 36601152 36601190 39 + 2.097 2.018 -0.267
ENSG00000112081 E016 2.0660252 1.033628e-01 6.831655e-01 8.687394e-01 6 36601191 36601707 517 + 0.519 0.450 -0.343
ENSG00000112081 E017 179.9266866 1.251150e-04 5.421731e-03 5.249832e-02 6 36601708 36601794 87 + 2.286 2.225 -0.202
ENSG00000112081 E018 2.5114149 1.046064e-02 8.679372e-03 7.315413e-02 6 36601795 36601961 167 + 0.692 0.309 -1.916
ENSG00000112081 E019 801.7739378 6.408179e-05 4.427051e-01 7.179713e-01 6 36601962 36605600 3639 + 2.907 2.902 -0.019

Help

Please Click HERE to learn more details about the results from DEXseq.