ENSG00000112200

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370706 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding protein_coding 24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 7.5409783 7.0643793 8.3141614 0.57265613 0.2096844 0.2347014 0.35284167 0.240600 0.442775 0.202175 0.1983418712 0.0001397128 FALSE TRUE
ENST00000370708 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding protein_coding 24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 2.9780736 2.4052154 3.6146027 0.08664727 0.1175142 0.5856710 0.14292500 0.084975 0.192525 0.107550 0.2613866618 0.0001397128 FALSE TRUE
ENST00000370710 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding protein_coding 24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 0.9312707 0.0000000 1.0553504 0.00000000 0.6093188 6.7351841 0.04464167 0.000000 0.055475 0.055475 0.3586304862 0.0001397128   FALSE
ENST00000444273 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding retained_intron 24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 1.0413955 0.5662641 0.9941687 0.32813544 0.2803515 0.8011996 0.05075000 0.019625 0.052850 0.033225 0.5235513434 0.0001397128 FALSE TRUE
ENST00000504364 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding retained_intron 24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 2.2557433 4.9476799 0.0000000 0.74061151 0.0000000 -8.9535213 0.09199167 0.184925 0.000000 -0.184925 0.0001397128 0.0001397128   FALSE
MSTRG.24824.19 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding   24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 4.6072572 13.8217715 0.0000000 7.98003308 0.0000000 -10.4337702 0.09830000 0.294900 0.000000 -0.294900 0.7931880452 0.0001397128   FALSE
MSTRG.24824.21 ENSG00000112200 No_inf pgKDN_inf ZNF451 protein_coding   24.14003 33.995 18.80492 7.557681 0.6547898 -0.8538699 2.7657971 2.2889902 2.9857429 0.77202152 1.1274184 0.3819135 0.13476667 0.087775 0.158650 0.070875 0.8597002554 0.0001397128   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112200 E001 0.1272623 0.0123181487 5.211944e-01   6 57086844 57086908 65 + 0.000 0.096 9.682
ENSG00000112200 E002 0.0000000       6 57090010 57090029 20 +      
ENSG00000112200 E003 0.0000000       6 57090030 57090075 46 +      
ENSG00000112200 E004 0.0000000       6 57090076 57090076 1 +      
ENSG00000112200 E005 0.1186381 0.0117860509 5.556153e-01   6 57090077 57090112 36 + 0.094 0.000 -12.544
ENSG00000112200 E006 0.2457744 0.0161172081 9.790912e-01   6 57090113 57090138 26 + 0.094 0.096 0.042
ENSG00000112200 E007 0.9706409 0.0120752015 5.122421e-01 7.691995e-01 6 57090139 57090168 30 + 0.344 0.242 -0.695
ENSG00000112200 E008 1.0962691 0.1382667611 8.058926e-01 9.281010e-01 6 57090169 57090187 19 + 0.343 0.300 -0.278
ENSG00000112200 E009 1.0962691 0.1382667611 8.058926e-01 9.281010e-01 6 57090188 57090188 1 + 0.343 0.300 -0.278
ENSG00000112200 E010 1.8185550 0.1608592557 6.636730e-01 8.600942e-01 6 57090189 57090206 18 + 0.501 0.396 -0.540
ENSG00000112200 E011 1.8186811 0.2279240450 6.739418e-01 8.649499e-01 6 57090207 57090210 4 + 0.501 0.396 -0.540
ENSG00000112200 E012 2.8075753 0.0922970767 9.590866e-01 9.903609e-01 6 57090211 57090224 14 + 0.590 0.572 -0.082
ENSG00000112200 E013 4.2684193 0.0839692302 7.880931e-01 9.187448e-01 6 57090225 57090274 50 + 0.747 0.697 -0.205
ENSG00000112200 E014 0.0000000       6 57090783 57090810 28 +      
ENSG00000112200 E015 2.9388975 0.0160574691 9.387645e-01 9.823356e-01 6 57090811 57090832 22 + 0.590 0.600 0.042
ENSG00000112200 E016 3.8923586 0.0073539623 3.442203e-01 6.355544e-01 6 57090833 57090894 62 + 0.747 0.626 -0.505
ENSG00000112200 E017 0.0000000       6 57091430 57091452 23 +      
ENSG00000112200 E018 0.1265070 0.0122356034 5.213046e-01   6 57092785 57093051 267 + 0.000 0.096 11.709
ENSG00000112200 E019 4.5256764 0.0036635866 9.527947e-01 9.883484e-01 6 57099061 57099141 81 + 0.747 0.738 -0.036
ENSG00000112200 E020 0.3516386 0.0200164737 1.105299e-01   6 57099469 57099568 100 + 0.236 0.000 -13.982
ENSG00000112200 E021 0.2352613 0.2686592518 3.121097e-01   6 57099569 57099610 42 + 0.171 0.000 -12.919
ENSG00000112200 E022 21.6472591 0.0150077309 1.054589e-01 3.397540e-01 6 57100603 57102319 1717 + 1.416 1.287 -0.448
ENSG00000112200 E023 3.0500942 0.0243325928 6.335508e-01 8.432825e-01 6 57102320 57102560 241 + 0.641 0.572 -0.306
ENSG00000112200 E024 4.8862887 0.0032191612 8.361918e-01 9.412525e-01 6 57102561 57102879 319 + 0.783 0.757 -0.102
ENSG00000112200 E025 113.1821093 0.0001646740 2.030925e-05 6.252049e-04 6 57102880 57109716 6837 + 2.109 2.002 -0.361
ENSG00000112200 E026 0.2459004 0.0160993649 9.791812e-01   6 57124429 57124733 305 + 0.094 0.096 0.042
ENSG00000112200 E027 3.5648480 0.0044205288 5.214082e-01 7.753627e-01 6 57124734 57124859 126 + 0.617 0.697 0.342
ENSG00000112200 E028 0.0000000       6 57126532 57126599 68 +      
ENSG00000112200 E029 0.1268540 0.0122871088 5.212026e-01   6 57126650 57126707 58 + 0.000 0.096 11.709
ENSG00000112200 E030 4.2524708 0.0318478067 3.431476e-01 6.344242e-01 6 57128729 57128840 112 + 0.783 0.651 -0.543
ENSG00000112200 E031 8.0709396 0.0017638878 9.126518e-01 9.722813e-01 6 57133042 57133192 151 + 0.964 0.952 -0.045
ENSG00000112200 E032 6.1048398 0.0023292494 6.569035e-01 8.564247e-01 6 57134744 57134870 127 + 0.876 0.827 -0.189
ENSG00000112200 E033 6.6627159 0.0020868923 2.965812e-02 1.619127e-01 6 57141302 57141455 154 + 0.986 0.757 -0.880
ENSG00000112200 E034 6.5539905 0.0223277326 1.780901e-01 4.528792e-01 6 57141948 57142095 148 + 0.952 0.793 -0.610
ENSG00000112200 E035 51.2560751 0.0084036469 2.534243e-01 5.449617e-01 6 57147090 57148693 1604 + 1.748 1.687 -0.206
ENSG00000112200 E036 0.0000000       6 57150719 57150862 144 +      
ENSG00000112200 E037 1.3392379 0.4449046623 6.601638e-01 8.581239e-01 6 57150863 57151371 509 + 0.430 0.300 -0.768
ENSG00000112200 E038 0.7355302 0.0143473866 9.678528e-01 9.935041e-01 6 57152157 57152220 64 + 0.236 0.242 0.042
ENSG00000112200 E039 11.3290842 0.0012920278 2.356742e-01 5.250489e-01 6 57152221 57152351 131 + 1.139 1.039 -0.364
ENSG00000112200 E040 19.4643617 0.0007852323 8.930184e-01 9.645020e-01 6 57153861 57154047 187 + 1.307 1.314 0.024
ENSG00000112200 E041 2.3752792 0.0061183576 8.152544e-03 6.998238e-02 6 57154048 57154544 497 + 0.293 0.674 1.949
ENSG00000112200 E042 1.8490181 0.0257652234 4.199660e-01 6.993684e-01 6 57158465 57158674 210 + 0.389 0.510 0.627
ENSG00000112200 E043 2.6493817 0.0556192115 3.050405e-04 5.884654e-03 6 57160808 57161083 276 + 0.171 0.757 3.290
ENSG00000112200 E044 10.5812268 0.0072751091 2.418050e-01 5.315038e-01 6 57161084 57161152 69 + 1.007 1.111 0.379
ENSG00000112200 E045 136.9654360 0.0005209461 1.383195e-11 1.541348e-09 6 57168423 57170305 1883 + 2.056 2.207 0.508

Help

Please Click HERE to learn more details about the results from DEXseq.