ENSG00000112339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367820 ENSG00000112339 No_inf pgKDN_inf HBS1L protein_coding protein_coding 40.42793 27.07588 49.66607 1.718406 3.863545 0.8750103 4.075144 2.498684 8.008867 1.748267 4.652961 1.6764677 0.08823333 0.083650 0.143950 0.060300 1.00000000 0.01004025 FALSE TRUE
ENST00000367826 ENSG00000112339 No_inf pgKDN_inf HBS1L protein_coding protein_coding 40.42793 27.07588 49.66607 1.718406 3.863545 0.8750103 12.588746 5.622738 15.700225 2.600951 2.509156 1.4797955 0.29669167 0.207625 0.310800 0.103175 0.74987869 0.01004025 FALSE TRUE
ENST00000526100 ENSG00000112339 No_inf pgKDN_inf HBS1L protein_coding nonsense_mediated_decay 40.42793 27.07588 49.66607 1.718406 3.863545 0.8750103 3.577966 0.000000 1.562414 0.000000 1.562414 7.2968371 0.08235000 0.000000 0.037600 0.037600 0.93098140 0.01004025 FALSE TRUE
ENST00000533274 ENSG00000112339 No_inf pgKDN_inf HBS1L protein_coding protein_coding 40.42793 27.07588 49.66607 1.718406 3.863545 0.8750103 5.332750 0.000000 12.048421 0.000000 4.261879 10.2358253 0.10565833 0.000000 0.231700 0.231700 0.01004025 0.01004025 FALSE TRUE
MSTRG.25333.2 ENSG00000112339 No_inf pgKDN_inf HBS1L protein_coding   40.42793 27.07588 49.66607 1.718406 3.863545 0.8750103 4.927786 11.203809 2.801028 2.840408 2.216573 -1.9961068 0.16299167 0.406475 0.065175 -0.341300 0.04521159 0.01004025 FALSE TRUE
MSTRG.25333.3 ENSG00000112339 No_inf pgKDN_inf HBS1L protein_coding   40.42793 27.07588 49.66607 1.718406 3.863545 0.8750103 6.836973 4.609219 6.578063 1.778020 3.803298 0.5122054 0.17924167 0.178750 0.150500 -0.028250 0.83537059 0.01004025 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112339 E001 8.5306885 0.0015813942 0.0001277383 0.002895938 6 134960378 134964628 4251 - 0.783 1.146 1.358
ENSG00000112339 E002 0.1265070 0.0123131178 0.3655252878   6 134964629 134964630 2 - 0.000 0.112 11.573
ENSG00000112339 E003 0.1265070 0.0123131178 0.3655252878   6 134964631 134964632 2 - 0.000 0.112 11.573
ENSG00000112339 E004 13.9078190 0.0014940252 0.0007413121 0.011895842 6 134964633 134964841 209 - 1.039 1.299 0.927
ENSG00000112339 E005 59.0891806 0.0002733654 0.2723349212 0.566067902 6 134964842 134965148 307 - 1.756 1.797 0.141
ENSG00000112339 E006 48.3993342 0.0004276766 0.9145063344 0.973093890 6 134965149 134965290 142 - 1.691 1.686 -0.016
ENSG00000112339 E007 40.7190117 0.0003907299 0.7892331208 0.919124614 6 134966329 134966473 145 - 1.621 1.608 -0.043
ENSG00000112339 E008 32.1661236 0.0004260522 0.3822017014 0.668450177 6 134969238 134969338 101 - 1.535 1.489 -0.157
ENSG00000112339 E009 37.2392036 0.0003834136 0.7756414304 0.913805971 6 134978679 134978787 109 - 1.572 1.586 0.047
ENSG00000112339 E010 32.8675574 0.0004372798 0.6992149775 0.877439228 6 134979178 134979268 91 - 1.516 1.536 0.068
ENSG00000112339 E011 0.0000000       6 134982293 134982457 165 -      
ENSG00000112339 E012 27.0564009 0.0005343593 0.3637795026 0.652625426 6 134982458 134982562 105 - 1.421 1.472 0.176
ENSG00000112339 E013 0.7522443 0.0130661530 0.0337462730 0.174822967 6 134982563 134983573 1011 - 0.080 0.394 2.864
ENSG00000112339 E014 17.5920386 0.0007902019 0.1142261361 0.355943634 6 134985341 134985409 69 - 1.215 1.324 0.382
ENSG00000112339 E015 22.3147142 0.0009705601 0.3323304514 0.624461226 6 134986066 134986183 118 - 1.336 1.397 0.209
ENSG00000112339 E016 17.5480758 0.0012445697 0.5710783457 0.807311268 6 134986736 134986810 75 - 1.246 1.286 0.139
ENSG00000112339 E017 12.5833521 0.0012890691 0.2296521224 0.518247380 6 134987645 134987653 9 - 1.085 1.181 0.346
ENSG00000112339 E018 32.3014281 0.0021119031 0.2189515104 0.505714135 6 134987654 134987791 138 - 1.489 1.555 0.225
ENSG00000112339 E019 24.1314842 0.0009556408 0.3128143769 0.606169576 6 134993758 134993875 118 - 1.421 1.359 -0.214
ENSG00000112339 E020 12.8830850 0.0011284102 0.8210937155 0.935029527 6 134996777 134996821 45 - 1.146 1.127 -0.066
ENSG00000112339 E021 25.8767739 0.0006177443 0.7030400300 0.879191267 6 134996822 134996942 121 - 1.434 1.412 -0.077
ENSG00000112339 E022 14.6204684 0.0031155410 0.0928918869 0.316609645 6 134997397 134997421 25 - 1.241 1.108 -0.476
ENSG00000112339 E023 40.3447721 0.0003732188 0.0585739236 0.242450191 6 134997422 134997656 235 - 1.647 1.558 -0.305
ENSG00000112339 E024 0.0000000       6 135002621 135002733 113 -      
ENSG00000112339 E025 16.4199964 0.0008719624 0.9943582611 1.000000000 6 135002734 135002781 48 - 1.236 1.237 0.001
ENSG00000112339 E026 14.1537821 0.0009429989 0.3701530140 0.658437753 6 135002782 135002814 33 - 1.146 1.214 0.242
ENSG00000112339 E027 14.7450305 0.0009068238 0.6139739473 0.832184833 6 135002815 135002842 28 - 1.176 1.214 0.134
ENSG00000112339 E028 1.0079029 0.0745867783 0.0107291435 0.084120602 6 135010614 135010731 118 - 0.080 0.487 3.349
ENSG00000112339 E029 0.0000000       6 135026854 135026863 10 -      
ENSG00000112339 E030 0.1186381 0.0118447319 0.7880566166   6 135026864 135027066 203 - 0.080 0.000 -10.595
ENSG00000112339 E031 0.1186381 0.0118447319 0.7880566166   6 135027067 135027196 130 - 0.080 0.000 -10.595
ENSG00000112339 E032 7.0425839 0.0019359526 0.6677008620 0.861689643 6 135035857 135036695 839 - 0.919 0.875 -0.168
ENSG00000112339 E033 2.1446931 0.0115148930 0.0061955190 0.057771286 6 135036696 135036794 99 - 0.628 0.202 -2.458
ENSG00000112339 E034 9.8839899 0.0040618315 0.0201933641 0.127799683 6 135036795 135037810 1016 - 1.113 0.892 -0.817
ENSG00000112339 E035 1.6986808 0.0946674023 0.6986357339 0.877181760 6 135037811 135037848 38 - 0.451 0.394 -0.306
ENSG00000112339 E036 2.0670617 0.0072220445 0.9691657950 0.993641226 6 135037849 135038026 178 - 0.481 0.487 0.027
ENSG00000112339 E037 0.0000000       6 135038027 135038031 5 -      
ENSG00000112339 E038 29.6526033 0.0005292473 0.0373100875 0.185960841 6 135039573 135039767 195 - 1.527 1.412 -0.397
ENSG00000112339 E039 18.0100455 0.0007746022 0.0321962188 0.169798610 6 135042001 135042126 126 - 1.332 1.181 -0.531
ENSG00000112339 E040 15.2714392 0.0009221040 0.2506578458 0.541751757 6 135050582 135050647 66 - 1.241 1.155 -0.306
ENSG00000112339 E041 17.4602228 0.0210116318 0.3084191953 0.601623237 6 135054649 135054884 236 - 1.298 1.206 -0.326
ENSG00000112339 E042 0.0000000       6 135102928 135103056 129 -      

Help

Please Click HERE to learn more details about the results from DEXseq.