ENSG00000112514

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374484 ENSG00000112514 No_inf pgKDN_inf CUTA protein_coding nonsense_mediated_decay 148.5841 156.8864 141.7804 3.105932 6.057303 -0.1460526 9.551985 11.50141 0.00000 4.718858 0.000000 -10.16884844 0.06249167 0.071625 0.000000 -0.071625 7.719350e-03 3.494489e-22 TRUE TRUE
ENST00000440279 ENSG00000112514 No_inf pgKDN_inf CUTA protein_coding protein_coding 148.5841 156.8864 141.7804 3.105932 6.057303 -0.1460526 32.117635 28.58524 35.73820 4.162690 6.936228 0.32209579 0.21858333 0.181350 0.257425 0.076075 7.546733e-01 3.494489e-22 FALSE TRUE
ENST00000488034 ENSG00000112514 No_inf pgKDN_inf CUTA protein_coding protein_coding 148.5841 156.8864 141.7804 3.105932 6.057303 -0.1460526 30.005967 30.43103 28.64789 2.292370 3.089598 -0.08708485 0.20211667 0.194650 0.201475 0.006825 9.839883e-01 3.494489e-22 FALSE TRUE
ENST00000607266 ENSG00000112514 No_inf pgKDN_inf CUTA protein_coding protein_coding 148.5841 156.8864 141.7804 3.105932 6.057303 -0.1460526 50.404575 63.09971 45.38130 2.560312 8.457804 -0.47544625 0.33649167 0.402600 0.316275 -0.086325 5.245139e-01 3.494489e-22 FALSE TRUE
MSTRG.24552.5 ENSG00000112514 No_inf pgKDN_inf CUTA protein_coding   148.5841 156.8864 141.7804 3.105932 6.057303 -0.1460526 8.950308 0.00000 19.70312 0.000000 3.728098 10.94494051 0.06171667 0.000000 0.136600 0.136600 3.494489e-22 3.494489e-22 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112514 E001 0.0000000       6 33416442 33416484 43 -      
ENSG00000112514 E002 0.7368887 0.0433054416 0.760691655 0.90639678 6 33416485 33416541 57 - 0.264 0.216 -0.378
ENSG00000112514 E003 1.3446251 0.0099769610 0.471059419 0.73862143 6 33416542 33416549 8 - 0.427 0.317 -0.640
ENSG00000112514 E004 1.4718875 0.0093211054 0.658989517 0.85759288 6 33416550 33416550 1 - 0.427 0.360 -0.377
ENSG00000112514 E005 1.4718875 0.0093211054 0.658989517 0.85759288 6 33416551 33416551 1 - 0.427 0.360 -0.377
ENSG00000112514 E006 6.9366330 0.0022257894 0.236742263 0.52565996 6 33416552 33416560 9 - 0.818 0.941 0.471
ENSG00000112514 E007 41.8052303 0.0051782999 0.400876908 0.68411895 6 33416561 33416618 58 - 1.600 1.643 0.148
ENSG00000112514 E008 51.2204923 0.0041780678 0.836729169 0.94151820 6 33416619 33416660 42 - 1.707 1.715 0.028
ENSG00000112514 E009 89.3371457 0.0001959768 0.248228821 0.53905513 6 33416661 33416748 88 - 1.929 1.964 0.117
ENSG00000112514 E010 89.3691271 0.0001867595 0.189505715 0.46824268 6 33416749 33416776 28 - 1.926 1.966 0.134
ENSG00000112514 E011 1.6170250 0.0180356996 0.355812604 0.64553623 6 33416777 33416919 143 - 0.325 0.467 0.793
ENSG00000112514 E012 107.1212421 0.0001631074 0.139091790 0.39658366 6 33416920 33416969 50 - 2.004 2.044 0.136
ENSG00000112514 E013 2.1031945 0.0406191323 0.530668331 0.78163231 6 33416970 33417096 127 - 0.427 0.527 0.498
ENSG00000112514 E014 99.9450073 0.0001785188 0.782331228 0.91627041 6 33417097 33417142 46 - 1.994 2.001 0.024
ENSG00000112514 E015 1.6071408 0.0084952857 0.711616474 0.88347977 6 33417143 33417246 104 - 0.379 0.434 0.301
ENSG00000112514 E016 0.7526224 0.0141800087 0.167910884 0.43880533 6 33417247 33417250 4 - 0.107 0.317 1.945
ENSG00000112514 E017 86.8936180 0.0001887677 0.387832521 0.67353681 6 33417251 33417310 60 - 1.954 1.926 -0.095
ENSG00000112514 E018 1.1243074 0.0106431534 0.184390158 0.46157220 6 33417311 33417480 170 - 0.193 0.399 1.430
ENSG00000112514 E019 189.6438652 0.0000943886 0.003211292 0.03634792 6 33417481 33417695 215 - 2.308 2.248 -0.199
ENSG00000112514 E020 28.7415698 0.0293776545 0.747434712 0.90028883 6 33417696 33417816 121 - 1.485 1.455 -0.105
ENSG00000112514 E021 8.9271333 0.0280499969 0.248886657 0.53970139 6 33417817 33417868 52 - 1.064 0.930 -0.496
ENSG00000112514 E022 17.1788960 0.0055585991 0.343241060 0.63442428 6 33417869 33417958 90 - 1.294 1.222 -0.253
ENSG00000112514 E023 20.5807738 0.0007614700 0.558724506 0.80025089 6 33417959 33417983 25 - 1.306 1.343 0.129
ENSG00000112514 E024 19.6660321 0.0006873387 0.069900779 0.26746093 6 33417984 33418010 27 - 1.235 1.356 0.423
ENSG00000112514 E025 19.5236370 0.0007396242 0.155327663 0.42121241 6 33418011 33418086 76 - 1.249 1.343 0.331
ENSG00000112514 E026 24.0599792 0.0074616536 0.011827589 0.08972133 6 33418087 33418201 115 - 1.485 1.313 -0.597
ENSG00000112514 E027 0.8630785 0.0127956611 0.970102547 0.99395450 6 33418202 33418317 116 - 0.264 0.269 0.038

Help

Please Click HERE to learn more details about the results from DEXseq.