ENSG00000112531

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361195 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding protein_coding 90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 15.076944 10.422719 17.552423 3.826587 3.094083 0.7513767 0.17090833 0.158100 0.147200 -0.010900 0.960899372 0.007645145 FALSE  
ENST00000453779 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding protein_coding 90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 11.480912 6.120165 17.660290 2.853063 2.765810 1.5273279 0.12520833 0.097450 0.146700 0.049250 0.715439236 0.007645145 FALSE  
ENST00000541696 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding retained_intron 90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 1.999736 4.678841 0.000000 1.705639 0.000000 -8.8730876 0.02839167 0.070400 0.000000 -0.070400 0.007645145 0.007645145    
ENST00000544361 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding protein_coding 90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 9.263655 9.728205 10.730135 1.624797 1.835742 0.1412844 0.10709167 0.143475 0.090500 -0.052975 0.566839878 0.007645145 FALSE  
ENST00000544823 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding protein_coding 90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 23.150408 10.707355 33.567026 2.482472 4.219719 1.6475256 0.24407500 0.154725 0.279625 0.124900 0.193302937 0.007645145 FALSE  
MSTRG.25637.11 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding   90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 8.821656 6.776817 16.999037 3.084202 3.764565 1.3254945 0.09280000 0.096950 0.147450 0.050500 0.806932328 0.007645145 FALSE  
MSTRG.25637.17 ENSG00000112531 No_inf pgKDN_inf QKI protein_coding   90.09934 67.28039 118.9463 3.477071 4.803627 0.8219595 3.377968 6.381920 3.143986 1.112674 1.292541 -1.0190733 0.04249167 0.094750 0.025600 -0.069150 0.103731462 0.007645145 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112531 E001 0.0000000       6 163414000 163414004 5 +      
ENSG00000112531 E002 4.3715017 1.180386e-02 7.339680e-01 8.943636e-01 6 163414005 163414642 638 + 0.745 0.703 -0.175
ENSG00000112531 E003 1.9415349 6.823961e-03 7.284132e-01 8.916936e-01 6 163414643 163414717 75 + 0.488 0.437 -0.260
ENSG00000112531 E004 32.5700568 2.210159e-03 3.024501e-02 1.635819e-01 6 163414718 163415169 452 + 1.572 1.449 -0.419
ENSG00000112531 E005 16.2441529 9.727101e-04 1.612851e-01 4.293901e-01 6 163415170 163415193 24 + 1.275 1.172 -0.364
ENSG00000112531 E006 31.5017862 4.376832e-04 6.795506e-01 8.676012e-01 6 163415194 163415237 44 + 1.518 1.496 -0.075
ENSG00000112531 E007 47.1691778 3.031652e-04 4.573573e-01 7.292567e-01 6 163415238 163415335 98 + 1.693 1.661 -0.111
ENSG00000112531 E008 1.3406250 1.015976e-02 8.097386e-01 9.298226e-01 6 163416315 163416486 172 + 0.351 0.388 0.214
ENSG00000112531 E009 0.0000000       6 163423134 163423207 74 +      
ENSG00000112531 E010 0.0000000       6 163423208 163423213 6 +      
ENSG00000112531 E011 0.3641302 2.246919e-01 8.506218e-01   6 163423214 163423592 379 + 0.151 0.110 -0.524
ENSG00000112531 E012 0.2447669 1.657308e-02 7.977405e-01   6 163428995 163429017 23 + 0.082 0.110 0.477
ENSG00000112531 E013 0.1170040 1.173567e-02 7.494615e-01   6 163455216 163455278 63 + 0.082 0.000 -10.620
ENSG00000112531 E014 33.4972946 4.185364e-04 1.645090e-01 4.337981e-01 6 163455279 163455330 52 + 1.564 1.492 -0.249
ENSG00000112531 E015 60.0159523 2.520574e-04 1.743487e-02 1.157617e-01 6 163455331 163455421 91 + 1.820 1.726 -0.318
ENSG00000112531 E016 1.2240968 1.537481e-02 6.094143e-01 8.300727e-01 6 163457381 163457551 171 + 0.309 0.388 0.477
ENSG00000112531 E017 78.2410631 2.940956e-04 5.736715e-06 2.114860e-04 6 163478780 163478896 117 + 1.958 1.798 -0.540
ENSG00000112531 E018 0.2340080 2.633588e-01 4.442311e-01   6 163534959 163534981 23 + 0.151 0.000 -10.501
ENSG00000112531 E019 69.2738305 2.404510e-04 5.998700e-04 1.005701e-02 6 163534982 163535079 98 + 1.894 1.767 -0.429
ENSG00000112531 E020 44.2751475 8.585901e-04 7.399409e-01 8.968699e-01 6 163535080 163535125 46 + 1.659 1.644 -0.052
ENSG00000112531 E021 68.9954432 3.905504e-03 3.179075e-01 6.106350e-01 6 163561982 163562069 88 + 1.861 1.816 -0.152
ENSG00000112531 E022 29.7766768 1.450033e-02 7.879184e-01 9.186636e-01 6 163563420 163563422 3 + 1.495 1.471 -0.083
ENSG00000112531 E023 37.5302686 1.751667e-03 3.144207e-01 6.074423e-01 6 163563423 163563443 21 + 1.604 1.552 -0.178
ENSG00000112531 E024 117.6606109 1.393168e-04 2.878343e-02 1.589659e-01 6 163563444 163563719 276 + 2.096 2.035 -0.205
ENSG00000112531 E025 20.5583231 7.215759e-04 1.077525e-04 2.524554e-03 6 163563720 163564666 947 + 1.202 1.454 0.877
ENSG00000112531 E026 57.1879296 4.865634e-04 3.791576e-04 7.005647e-03 6 163564667 163565945 1279 + 1.693 1.836 0.483
ENSG00000112531 E027 25.8679337 3.877068e-03 3.704933e-01 6.588122e-01 6 163565946 163566067 122 + 1.450 1.392 -0.199
ENSG00000112531 E028 66.3533936 2.260165e-04 4.521430e-04 8.080146e-03 6 163566068 163566457 390 + 1.878 1.745 -0.448
ENSG00000112531 E029 57.7167358 4.789014e-04 1.805090e-04 3.843495e-03 6 163566458 163566720 263 + 1.826 1.671 -0.523
ENSG00000112531 E030 56.1282821 2.780358e-04 1.811818e-01 4.570381e-01 6 163566721 163566795 75 + 1.776 1.722 -0.184
ENSG00000112531 E031 529.5429652 5.527757e-05 2.193355e-02 1.344538e-01 6 163566796 163569437 2642 + 2.733 2.705 -0.093
ENSG00000112531 E032 185.5412265 1.264770e-04 9.690674e-01 9.936412e-01 6 163569438 163570145 708 + 2.267 2.268 0.003
ENSG00000112531 E033 930.6940108 4.962688e-05 8.730345e-22 2.836521e-19 6 163570694 163578592 7899 + 2.929 3.009 0.263

Help

Please Click HERE to learn more details about the results from DEXseq.