ENSG00000112584

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000476287 ENSG00000112584 No_inf pgKDN_inf FAM120B protein_coding protein_coding 17.63332 15.96016 19.16119 0.9409076 0.8199726 0.2635608 5.9850139 8.460721 4.3884602 0.8381709 1.6068506 -0.9454863 0.3565667 0.538150 0.235125 -0.303025 0.42708486 0.01897463 FALSE TRUE
ENST00000496635 ENSG00000112584 No_inf pgKDN_inf FAM120B protein_coding protein_coding_CDS_not_defined 17.63332 15.96016 19.16119 0.9409076 0.8199726 0.2635608 0.8767098 1.480982 0.3138403 0.4457188 0.1813394 -2.2029085 0.0507500 0.090875 0.015975 -0.074900 0.24291878 0.01897463   FALSE
MSTRG.25689.3 ENSG00000112584 No_inf pgKDN_inf FAM120B protein_coding   17.63332 15.96016 19.16119 0.9409076 0.8199726 0.2635608 7.8987988 4.142965 10.3309607 0.5092617 0.9245844 1.3161567 0.4353667 0.256300 0.535900 0.279600 0.01897463 0.01897463 FALSE TRUE
MSTRG.25689.6 ENSG00000112584 No_inf pgKDN_inf FAM120B protein_coding   17.63332 15.96016 19.16119 0.9409076 0.8199726 0.2635608 0.4353935 0.000000 1.3061806 0.0000000 0.9717479 7.0402136 0.0220500 0.000000 0.066150 0.066150 0.52833471 0.01897463 FALSE TRUE
MSTRG.25689.7 ENSG00000112584 No_inf pgKDN_inf FAM120B protein_coding   17.63332 15.96016 19.16119 0.9409076 0.8199726 0.2635608 2.1944312 1.875494 2.3318827 0.5563840 0.6021891 0.3127259 0.1224833 0.114700 0.123100 0.008400 0.99253040 0.01897463 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112584 E001 0.000000       6 170290703 170291072 370 +      
ENSG00000112584 E002 0.000000       6 170295321 170295453 133 +      
ENSG00000112584 E003 0.497781 0.0215845283 3.653482e-01   6 170306736 170306757 22 + 0.099 0.231 1.454
ENSG00000112584 E004 0.371274 0.0165795677 6.389090e-01   6 170306758 170306760 3 + 0.099 0.167 0.869
ENSG00000112584 E005 1.700038 0.0103033418 4.911832e-01 7.535406e-01 6 170306761 170306784 24 + 0.484 0.381 -0.546
ENSG00000112584 E006 7.276045 0.0140553338 2.443905e-02 1.434272e-01 6 170306785 170306842 58 + 1.031 0.789 -0.919
ENSG00000112584 E007 88.273900 0.0002302685 3.148669e-06 1.255139e-04 6 170317370 170318462 1093 + 2.018 1.881 -0.459
ENSG00000112584 E008 33.243376 0.0074242237 9.775792e-02 3.259242e-01 6 170318463 170318786 324 + 1.584 1.484 -0.343
ENSG00000112584 E009 37.842712 0.0004315916 3.767740e-02 1.872379e-01 6 170318787 170319124 338 + 1.639 1.540 -0.336
ENSG00000112584 E010 23.470519 0.0028658020 3.204706e-01 6.133750e-01 6 170323079 170323259 181 + 1.421 1.357 -0.221
ENSG00000112584 E011 13.007398 0.0022134356 1.405841e-02 1.003742e-01 6 170330449 170330550 102 + 1.240 1.044 -0.704
ENSG00000112584 E012 22.320939 0.0008619786 6.337516e-02 2.533262e-01 6 170348151 170348323 173 + 1.425 1.310 -0.399
ENSG00000112584 E013 15.096609 0.0037452527 8.915489e-01 9.639673e-01 6 170358226 170358318 93 + 1.200 1.210 0.034
ENSG00000112584 E014 3.067030 0.0057119658 9.842066e-01 9.987279e-01 6 170358319 170358420 102 + 0.610 0.607 -0.015
ENSG00000112584 E015 28.840572 0.0010446050 9.589427e-01 9.903220e-01 6 170388287 170388493 207 + 1.473 1.474 0.004
ENSG00000112584 E016 19.087279 0.0007529825 1.377618e-01 3.950394e-01 6 170391013 170391121 109 + 1.247 1.343 0.339
ENSG00000112584 E017 1.633735 0.0090863770 1.453806e-02 1.028592e-01 6 170391122 170391164 43 + 0.180 0.553 2.329
ENSG00000112584 E018 15.393688 0.0009625670 1.602912e-01 4.279986e-01 6 170395487 170395579 93 + 1.156 1.257 0.359
ENSG00000112584 E019 2.865987 0.0104516190 3.705435e-02 1.853714e-01 6 170404179 170404549 371 + 0.404 0.697 1.372
ENSG00000112584 E020 12.080630 0.0012097156 1.636891e-01 4.326512e-01 6 170404550 170404601 52 + 1.051 1.163 0.405
ENSG00000112584 E021 107.599041 0.0002132989 3.523292e-14 5.540095e-12 6 170404763 170407067 2305 + 1.916 2.114 0.665

Help

Please Click HERE to learn more details about the results from DEXseq.