ENSG00000112697

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000230461 ENSG00000112697 No_inf pgKDN_inf TMEM30A protein_coding protein_coding 179.6687 201.1381 189.2271 1.4426 1.855653 -0.08806269 105.71579 102.70486 113.28458 2.032912 3.562657 0.1414339 0.59668333 0.510725 0.598525 0.0878 0.13136440 0.04386525 FALSE TRUE
ENST00000370050 ENSG00000112697 No_inf pgKDN_inf TMEM30A protein_coding protein_coding 179.6687 201.1381 189.2271 1.4426 1.855653 -0.08806269 10.20404 0.00000 11.57304 0.000000 7.206666 10.1777976 0.06273333 0.000000 0.060200 0.0602 0.74258513 0.04386525 FALSE TRUE
ENST00000674151 ENSG00000112697 No_inf pgKDN_inf TMEM30A protein_coding protein_coding 179.6687 201.1381 189.2271 1.4426 1.855653 -0.08806269 62.38656 97.45377 62.85534 3.223560 6.379890 -0.6326012 0.33272500 0.484375 0.333275 -0.1511 0.04386525 0.04386525 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112697 E001 2.1964681 6.366290e-03 4.184232e-01 6.980467e-01 6 75252924 75252936 13 - 0.563 0.448 -0.561
ENSG00000112697 E002 3.3213109 4.183450e-03 8.812196e-01 9.600391e-01 6 75252937 75252947 11 - 0.622 0.641 0.083
ENSG00000112697 E003 3.3213109 4.183450e-03 8.812196e-01 9.600391e-01 6 75252948 75252948 1 - 0.622 0.641 0.083
ENSG00000112697 E004 8.1807573 1.746044e-03 4.053963e-02 1.953072e-01 6 75252949 75252963 15 - 0.836 1.038 0.761
ENSG00000112697 E005 444.9201486 8.068872e-05 5.952483e-78 2.675344e-74 6 75252964 75253612 649 - 2.469 2.748 0.928
ENSG00000112697 E006 1484.0377319 5.633335e-05 1.777730e-14 2.905457e-12 6 75253613 75254598 986 - 3.138 3.192 0.179
ENSG00000112697 E007 566.9998530 6.289065e-05 4.124233e-02 1.971604e-01 6 75254599 75255062 464 - 2.765 2.740 -0.086
ENSG00000112697 E008 1319.3131041 2.577122e-05 1.345098e-15 2.402202e-13 6 75255063 75256295 1233 - 3.150 3.091 -0.196
ENSG00000112697 E009 245.4509063 8.021267e-05 2.637100e-06 1.077495e-04 6 75258780 75258986 207 - 2.437 2.346 -0.302
ENSG00000112697 E010 134.0903849 2.211871e-03 7.720335e-03 6.747505e-02 6 75259347 75259441 95 - 2.174 2.087 -0.291
ENSG00000112697 E011 80.9886955 3.183278e-03 3.594271e-02 1.818512e-01 6 75259442 75259490 49 - 1.957 1.871 -0.291
ENSG00000112697 E012 0.0000000       6 75260122 75260402 281 -      
ENSG00000112697 E013 111.7949166 1.610887e-03 1.180813e-04 2.725116e-03 6 75260824 75260911 88 - 2.116 1.989 -0.425
ENSG00000112697 E014 133.6930651 9.111063e-04 2.979887e-05 8.607581e-04 6 75265231 75265338 108 - 2.189 2.069 -0.402
ENSG00000112697 E015 124.8320265 1.454928e-04 4.537592e-05 1.231039e-03 6 75267641 75267748 108 - 2.155 2.044 -0.372
ENSG00000112697 E016 0.4720409 1.595337e-02 3.039862e-02   6 75272464 75272900 437 - 0.315 0.000 -11.900
ENSG00000112697 E017 0.1187032 1.184928e-02 4.561503e-01   6 75283897 75284014 118 - 0.102 0.000 -10.048
ENSG00000112697 E018 0.9805831 1.867486e-02 8.189901e-01 9.340737e-01 6 75284220 75284401 182 - 0.315 0.279 -0.239
ENSG00000112697 E019 117.3332198 1.405523e-04 1.601677e-01 4.278229e-01 6 75284402 75284496 95 - 2.092 2.052 -0.133
ENSG00000112697 E020 165.8597302 3.952159e-04 1.013760e-03 1.516254e-02 6 75284497 75284948 452 - 2.263 2.182 -0.271

Help

Please Click HERE to learn more details about the results from DEXseq.