ENSG00000112893

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261483 ENSG00000112893 No_inf pgKDN_inf MAN2A1 protein_coding protein_coding 14.76322 12.81783 16.24023 0.2778839 0.5625406 0.3411828 12.1293759 8.133542 15.0422438 0.6528215 0.74353468 0.8862503 0.8097667 0.634350 0.92535 0.291000 0.002078345 0.002078345 FALSE TRUE
ENST00000503970 ENSG00000112893 No_inf pgKDN_inf MAN2A1 protein_coding retained_intron 14.76322 12.81783 16.24023 0.2778839 0.5625406 0.3411828 0.6646879 1.287574 0.2494917 0.1784188 0.01861043 -2.3220563 0.0489250 0.100825 0.01540 -0.085425 0.058200879 0.002078345   FALSE
ENST00000513921 ENSG00000112893 No_inf pgKDN_inf MAN2A1 protein_coding retained_intron 14.76322 12.81783 16.24023 0.2778839 0.5625406 0.3411828 1.7851106 3.396716 0.9484946 0.6300401 0.40554262 -1.8295396 0.1303583 0.264850 0.05925 -0.205600 0.144649563 0.002078345 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112893 E001 9.7358804 0.0015760410 2.956438e-04 5.735702e-03 5 109689927 109690552 626 + 1.154 0.814 -1.267
ENSG00000112893 E002 6.7690788 0.0044255956 1.271681e-01 3.780763e-01 5 109713520 109713774 255 + 0.956 0.795 -0.619
ENSG00000112893 E003 5.3253371 0.0025856530 1.773559e-01 4.519496e-01 5 109716120 109716264 145 + 0.864 0.710 -0.609
ENSG00000112893 E004 9.6737819 0.0017902071 3.461747e-02 1.777982e-01 5 109729342 109729513 172 + 1.105 0.912 -0.712
ENSG00000112893 E005 7.4512903 0.0029514939 1.273334e-03 1.802623e-02 5 109755329 109755456 128 + 1.050 0.710 -1.306
ENSG00000112893 E006 9.3550505 0.0015209963 4.923922e-01 7.545883e-01 5 109767535 109767708 174 + 1.041 0.980 -0.227
ENSG00000112893 E007 6.7738490 0.0023224653 1.226329e-01 3.705990e-01 5 109770355 109770541 187 + 0.956 0.795 -0.619
ENSG00000112893 E008 6.6942503 0.0355033401 7.656795e-01 9.089251e-01 5 109774788 109774965 178 + 0.901 0.866 -0.135
ENSG00000112893 E009 8.8007189 0.0036108285 6.140141e-01 8.321917e-01 5 109781396 109781598 203 + 0.967 1.016 0.182
ENSG00000112893 E010 9.3176597 0.0015543227 6.449874e-02 2.559355e-01 5 109784744 109784926 183 + 1.082 0.912 -0.630
ENSG00000112893 E011 6.8339535 0.0029080365 9.397188e-01 9.828914e-01 5 109788934 109789048 115 + 0.889 0.897 0.032
ENSG00000112893 E012 6.8687019 0.0022367580 1.606810e-01 4.286787e-01 5 109789460 109789527 68 + 0.823 0.967 0.548
ENSG00000112893 E013 0.0000000       5 109794175 109794237 63 +      
ENSG00000112893 E014 0.1271363 0.0124617642 4.243080e-01   5 109804176 109804277 102 + 0.000 0.106 9.704
ENSG00000112893 E015 8.9647047 0.0016517617 1.835118e-01 4.603916e-01 5 109817273 109817438 166 + 1.050 0.926 -0.458
ENSG00000112893 E016 12.3569006 0.0016777868 4.476424e-02 2.069176e-01 5 109819669 109819887 219 + 1.192 1.027 -0.595
ENSG00000112893 E017 9.2705855 0.0015286250 9.206625e-01 9.752146e-01 5 109820220 109820342 123 + 1.006 1.016 0.037
ENSG00000112893 E018 7.9382689 0.0018002257 7.485446e-01 9.007185e-01 5 109823723 109823837 115 + 0.935 0.967 0.120
ENSG00000112893 E019 11.6988322 0.0012555011 7.755097e-01 9.138019e-01 5 109842328 109842461 134 + 1.113 1.090 -0.082
ENSG00000112893 E020 16.8754005 0.0009053777 2.054182e-01 4.886662e-01 5 109845865 109846006 142 + 1.290 1.201 -0.312
ENSG00000112893 E021 15.6973065 0.0009503857 6.004951e-01 8.250928e-01 5 109847657 109847790 134 + 1.238 1.201 -0.132
ENSG00000112893 E022 2.4946720 0.0113725334 6.275189e-03 5.832145e-02 5 109853581 109854921 1341 + 0.320 0.710 1.927
ENSG00000112893 E023 0.4999558 0.0153608529 2.189953e-01 5.057264e-01 5 109854922 109855139 218 + 0.085 0.262 1.927
ENSG00000112893 E024 19.9036217 0.0007155231 6.915815e-02 2.657056e-01 5 109855140 109855334 195 + 1.369 1.251 -0.414
ENSG00000112893 E025 6.1415375 0.0026927263 8.945301e-08 5.266986e-06 5 109862328 109865035 2708 + 0.471 1.080 2.494
ENSG00000112893 E026 15.6268579 0.0105897608 6.359524e-02 2.537693e-01 5 109865036 109865146 111 + 1.285 1.127 -0.559
ENSG00000112893 E027 0.0000000       5 109865147 109865415 269 +      
ENSG00000112893 E028 301.0184288 0.0001428679 8.100631e-07 3.849334e-05 5 109866846 109869625 2780 + 2.451 2.509 0.193

Help

Please Click HERE to learn more details about the results from DEXseq.