ENSG00000112983

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000230901 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding protein_coding 22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 0.9698363 0.000000 1.7224818 0.0000000 1.0221621 7.4366964 0.07256667 0.000000 0.123750 0.123750 0.356755223 0.008198635 FALSE TRUE
ENST00000402931 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding protein_coding 22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 2.3748700 3.580933 1.4809756 1.2400055 0.9077590 -1.2681022 0.09966667 0.104075 0.086375 -0.017700 0.867327606 0.008198635 FALSE TRUE
ENST00000441656 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding protein_coding 22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 2.1596373 3.906502 2.2613694 1.3971504 1.3075813 -0.7860032 0.08863333 0.114325 0.135825 0.021500 0.925505718 0.008198635 FALSE TRUE
ENST00000472478 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding nonsense_mediated_decay 22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 1.7725438 3.403339 0.8798753 0.9090581 0.5263002 -1.9395088 0.06873333 0.097500 0.052425 -0.045075 0.742843428 0.008198635   FALSE
ENST00000483805 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding retained_intron 22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 2.7140520 6.475109 0.2254976 1.2685632 0.2254976 -4.7833462 0.09544167 0.188825 0.013325 -0.175500 0.008198635 0.008198635 FALSE FALSE
MSTRG.23575.14 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding   22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 0.8307387 0.000000 1.2580140 0.0000000 1.2580140 6.9864269 0.05898333 0.000000 0.105525 0.105525 0.805891109 0.008198635 FALSE TRUE
MSTRG.23575.15 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding   22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 1.6823419 1.299314 1.1072970 1.2993141 0.6438560 -0.2287984 0.08975000 0.040850 0.066350 0.025500 0.713419234 0.008198635 TRUE TRUE
MSTRG.23575.9 ENSG00000112983 No_inf pgKDN_inf BRD8 protein_coding   22.25271 34.35438 15.54359 2.024145 1.258884 -1.143666 4.6662117 6.711573 3.4826593 1.2893892 0.3991277 -0.9444730 0.21705833 0.192050 0.229725 0.037675 0.873935013 0.008198635 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000112983 E001 0.0000000       5 138139770 138140166 397 -      
ENSG00000112983 E002 0.0000000       5 138140627 138140704 78 -      
ENSG00000112983 E003 0.1268540 0.0123238505 1.000000000   5 138140705 138140882 178 - 0.000 0.070 8.806
ENSG00000112983 E004 0.0000000       5 138145177 138145245 69 -      
ENSG00000112983 E005 0.1187032 0.0118716881 0.256574941   5 138145789 138145878 90 - 0.128 0.000 -13.550
ENSG00000112983 E006 0.0000000       5 138149640 138149797 158 -      
ENSG00000112983 E007 0.1271363 0.0123403720 1.000000000   5 138150745 138151008 264 - 0.000 0.070 11.316
ENSG00000112983 E008 0.0000000       5 138152482 138152760 279 -      
ENSG00000112983 E009 0.0000000       5 138156882 138156890 9 -      
ENSG00000112983 E010 0.2543986 0.0160733870 0.588603001   5 138156891 138156896 6 - 0.000 0.130 12.245
ENSG00000112983 E011 0.7633220 0.3017757861 0.147612958 0.40900885 5 138156897 138156913 17 - 0.000 0.311 13.255
ENSG00000112983 E012 1.1431900 0.0116147249 0.016278323 0.11082387 5 138156914 138156914 1 - 0.000 0.410 14.153
ENSG00000112983 E013 1.7698701 0.0114565571 0.020095683 0.12736082 5 138156915 138156932 18 - 0.128 0.514 2.724
ENSG00000112983 E014 3.5053123 0.0269643819 0.192463820 0.47234909 5 138156933 138156951 19 - 0.486 0.685 0.898
ENSG00000112983 E015 40.3533982 0.0004048305 0.480791546 0.74604642 5 138156952 138157267 316 - 1.607 1.578 -0.101
ENSG00000112983 E016 3.3709391 0.0044621200 0.203401210 0.48592491 5 138157642 138157894 253 - 0.486 0.669 0.831
ENSG00000112983 E017 4.4525096 0.0030771946 0.740943121 0.89714860 5 138159555 138159574 20 - 0.738 0.700 -0.154
ENSG00000112983 E018 5.5640436 0.0026048569 0.770432656 0.91150290 5 138159575 138159599 25 - 0.813 0.782 -0.119
ENSG00000112983 E019 13.8723054 0.0181237745 0.910497982 0.97167002 5 138160069 138160090 22 - 1.148 1.143 -0.016
ENSG00000112983 E020 23.5147746 0.0055709748 0.732575105 0.89370309 5 138160091 138160173 83 - 1.374 1.355 -0.067
ENSG00000112983 E021 10.6169152 0.0013415914 0.342272376 0.63369326 5 138160891 138160894 4 - 1.091 1.011 -0.293
ENSG00000112983 E022 17.2140967 0.0007841647 0.791335437 0.92008290 5 138160895 138160967 73 - 1.243 1.227 -0.054
ENSG00000112983 E023 16.1325293 0.0009181040 0.636587837 0.84488564 5 138160968 138161068 101 - 1.178 1.218 0.141
ENSG00000112983 E024 0.2533610 0.0160298414 0.588644673   5 138161069 138161235 167 - 0.000 0.130 12.245
ENSG00000112983 E025 14.4129233 0.0010095038 0.335882923 0.62776829 5 138161796 138161864 69 - 1.103 1.185 0.293
ENSG00000112983 E026 0.6260196 0.0148629257 0.527587207 0.77947921 5 138161865 138162051 187 - 0.128 0.230 1.023
ENSG00000112983 E027 0.1272623 0.0123781122 1.000000000   5 138162052 138162053 2 - 0.000 0.070 11.316
ENSG00000112983 E028 18.7921566 0.0262652143 0.242066147 0.53175283 5 138162054 138162146 93 - 1.188 1.301 0.399
ENSG00000112983 E029 0.0000000       5 138163129 138163129 1 -      
ENSG00000112983 E030 32.8545392 0.0004508781 0.925999701 0.97773821 5 138163130 138163344 215 - 1.494 1.504 0.031
ENSG00000112983 E031 0.1271363 0.0123403720 1.000000000   5 138163587 138163643 57 - 0.000 0.070 11.316
ENSG00000112983 E032 10.2456847 0.0033075696 0.238657170 0.52769068 5 138164087 138164133 47 - 1.091 0.988 -0.377
ENSG00000112983 E033 17.2451683 0.0008151640 0.782665432 0.91642303 5 138164320 138164413 94 - 1.216 1.241 0.086
ENSG00000112983 E034 37.1102259 0.0104421456 0.769358680 0.91087825 5 138164714 138165021 308 - 1.536 1.559 0.081
ENSG00000112983 E035 11.4422504 0.0012785494 0.398202725 0.68229710 5 138165022 138165111 90 - 1.012 1.091 0.291
ENSG00000112983 E036 8.7237698 0.0064721308 0.175013480 0.44886476 5 138165112 138165166 55 - 0.856 1.003 0.554
ENSG00000112983 E037 18.8024316 0.0086921371 0.643357787 0.84877716 5 138165828 138165998 171 - 1.291 1.258 -0.117
ENSG00000112983 E038 15.2402325 0.0012512964 0.972534693 0.99483520 5 138165999 138166108 110 - 1.178 1.185 0.023
ENSG00000112983 E039 4.0260721 0.0036036620 0.006687078 0.06109790 5 138166109 138166225 117 - 0.375 0.770 1.831
ENSG00000112983 E040 8.9375663 0.0713979887 0.890965525 0.96365730 5 138166518 138166610 93 - 0.949 0.980 0.114
ENSG00000112983 E041 12.3787348 0.0011480913 0.747774094 0.90051463 5 138166611 138166727 117 - 1.115 1.091 -0.084
ENSG00000112983 E042 12.2091746 0.0011516115 0.137568789 0.39485046 5 138166728 138167121 394 - 0.997 1.132 0.493
ENSG00000112983 E043 24.0872646 0.0005719912 0.443988008 0.71864738 5 138167122 138167642 521 - 1.335 1.387 0.182
ENSG00000112983 E044 11.0185448 0.0114581598 0.006615489 0.06059779 5 138167643 138167933 291 - 0.835 1.127 1.086
ENSG00000112983 E045 9.0191883 0.0015830619 0.530210568 0.78136447 5 138167934 138167986 53 - 1.012 0.955 -0.208
ENSG00000112983 E046 8.8894641 0.0015908695 0.337711958 0.62950704 5 138167987 138168078 92 - 1.026 0.938 -0.325
ENSG00000112983 E047 15.4002726 0.0010471676 0.037584107 0.18691205 5 138168470 138168688 219 - 1.283 1.132 -0.535
ENSG00000112983 E048 6.2584006 0.0023129341 0.046642289 0.21193372 5 138169222 138169262 41 - 0.966 0.757 -0.807
ENSG00000112983 E049 8.9986944 0.0014974010 0.175887318 0.44999320 5 138169263 138169349 87 - 1.053 0.930 -0.457
ENSG00000112983 E050 5.2787318 0.0025637036 0.079345459 0.28887660 5 138169350 138169358 9 - 0.896 0.700 -0.775
ENSG00000112983 E051 0.0000000       5 138169363 138169388 26 -      
ENSG00000112983 E052 7.9999853 0.0028566996 0.111697240 0.35104475 5 138170345 138170380 36 - 1.026 0.872 -0.575
ENSG00000112983 E053 7.9814194 0.0380085333 0.075740920 0.28122062 5 138170381 138170409 29 - 1.053 0.852 -0.754
ENSG00000112983 E054 0.0000000       5 138170730 138170831 102 -      
ENSG00000112983 E055 12.4180146 0.0246508998 0.092702946 0.31620546 5 138170832 138170912 81 - 1.207 1.039 -0.603
ENSG00000112983 E056 13.4695658 0.0011501754 0.479725445 0.74532355 5 138171038 138171160 123 - 1.168 1.115 -0.190
ENSG00000112983 E057 0.2541163 0.0160389898 0.588661660   5 138171345 138171360 16 - 0.000 0.130 12.245
ENSG00000112983 E058 7.7254873 0.0052482802 0.203674211 0.48629709 5 138171361 138171410 50 - 0.813 0.955 0.547
ENSG00000112983 E059 8.2267106 0.0227562076 0.153692091 0.41852112 5 138172065 138172134 70 - 0.812 0.988 0.667
ENSG00000112983 E060 0.0000000       5 138172720 138172826 107 -      
ENSG00000112983 E061 0.1187032 0.0118716881 0.256574941   5 138172827 138172851 25 - 0.128 0.000 -13.550
ENSG00000112983 E062 0.2545247 0.2872401241 0.661321798   5 138177164 138177565 402 - 0.000 0.130 11.834
ENSG00000112983 E063 0.0000000       5 138177566 138177570 5 -      
ENSG00000112983 E064 10.3959123 0.0015841199 0.665640540 0.86093106 5 138177571 138177667 97 - 1.053 1.018 -0.129
ENSG00000112983 E065 5.9536949 0.0030489367 0.985396543 0.99899506 5 138178596 138178953 358 - 0.813 0.818 0.023

Help

Please Click HERE to learn more details about the results from DEXseq.