ENSG00000113387

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265073 ENSG00000113387 No_inf pgKDN_inf SUB1 protein_coding protein_coding 38.62202 37.83956 41.74098 1.059091 4.003263 0.1415336 31.828408 32.8067422 33.396298 0.3286971 1.817162 0.0256881 0.82908333 0.868400 0.809975 -0.058425 0.6799317 0.0388325 FALSE  
ENST00000510442 ENSG00000113387 No_inf pgKDN_inf SUB1 protein_coding protein_coding 38.62202 37.83956 41.74098 1.059091 4.003263 0.1415336 3.457172 0.4660302 5.567489 0.4660302 3.223888 3.5504907 0.08001667 0.012250 0.114350 0.102100 0.7478611 0.0388325    
ENST00000511988 ENSG00000113387 No_inf pgKDN_inf SUB1 protein_coding retained_intron 38.62202 37.83956 41.74098 1.059091 4.003263 0.1415336 1.046828 2.5882685 0.000000 1.0611528 0.000000 -8.0214067 0.02701667 0.066475 0.000000 -0.066475 0.0388325 0.0388325    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000113387 E001 0.0000000       5 32531633 32531817 185 +      
ENSG00000113387 E002 0.0000000       5 32531818 32531848 31 +      
ENSG00000113387 E003 0.2441377 0.0165023885 0.9668985580   5 32531849 32531916 68 + 0.098 0.093 -0.081
ENSG00000113387 E004 0.0000000       5 32536638 32536695 58 +      
ENSG00000113387 E005 0.0000000       5 32571091 32571174 84 +      
ENSG00000113387 E006 1.3446215 0.0094710679 0.6986653816 0.87719856 5 32585557 32585558 2 + 0.400 0.340 -0.345
ENSG00000113387 E007 6.6032245 0.0034897915 0.6465363342 0.85038715 5 32585559 32585570 12 + 0.906 0.857 -0.188
ENSG00000113387 E008 27.7974820 0.0006279603 0.7374454729 0.89587765 5 32585571 32585587 17 + 1.469 1.449 -0.069
ENSG00000113387 E009 34.6192819 0.0005908082 0.3872026697 0.67309317 5 32585588 32585599 12 + 1.574 1.529 -0.153
ENSG00000113387 E010 53.6357865 0.0003346287 0.5707423866 0.80706965 5 32585600 32585625 26 + 1.749 1.725 -0.081
ENSG00000113387 E011 0.1271363 0.0123519152 0.5683652730   5 32585626 32585886 261 + 0.000 0.093 10.531
ENSG00000113387 E012 0.1170040 0.0116866575 0.5097195526   5 32585887 32585971 85 + 0.098 0.000 -11.560
ENSG00000113387 E013 0.3804973 0.0158729422 0.1139098240   5 32586114 32586368 255 + 0.000 0.234 12.035
ENSG00000113387 E014 0.1187032 0.0118120589 0.5097114403   5 32586369 32586428 60 + 0.098 0.000 -11.558
ENSG00000113387 E015 0.1187032 0.0118120589 0.5097114403   5 32586429 32586491 63 + 0.098 0.000 -11.558
ENSG00000113387 E016 0.1187032 0.0118120589 0.5097114403   5 32586492 32586501 10 + 0.098 0.000 -11.558
ENSG00000113387 E017 70.1466752 0.0002107752 0.3826557215 0.66885897 5 32588512 32588536 25 + 1.868 1.836 -0.107
ENSG00000113387 E018 84.0514810 0.0001905161 0.1395516267 0.39723298 5 32588537 32588584 48 + 1.954 1.906 -0.161
ENSG00000113387 E019 1.7403592 0.0300218239 0.1436126393 0.40354790 5 32591248 32591562 315 + 0.303 0.529 1.240
ENSG00000113387 E020 155.4273060 0.0021447040 0.1594188825 0.42681052 5 32591563 32591685 123 + 2.214 2.175 -0.131
ENSG00000113387 E021 0.0000000       5 32591686 32591687 2 +      
ENSG00000113387 E022 0.8515267 0.0126693537 0.6562061354 0.85607947 5 32594571 32594872 302 + 0.303 0.234 -0.496
ENSG00000113387 E023 17.4442853 0.0038395692 0.0027346581 0.03216817 5 32594923 32598960 4038 + 1.133 1.355 0.783
ENSG00000113387 E024 162.8993337 0.0001219343 0.3453458981 0.63638290 5 32598961 32599069 109 + 2.225 2.203 -0.073
ENSG00000113387 E025 317.1203452 0.0000871987 0.0008269585 0.01293913 5 32601005 32604079 3075 + 2.477 2.523 0.154

Help

Please Click HERE to learn more details about the results from DEXseq.