ENSG00000113580

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000394464 ENSG00000113580 No_inf pgKDN_inf NR3C1 protein_coding protein_coding 57.00864 78.94367 50.67097 2.100385 0.7727224 -0.6395623 6.000847 4.259283 5.500193 2.489757 1.9591566 0.3681090 0.1204333 0.053950 0.109025 0.055075 0.776497192 0.003326334 FALSE TRUE
MSTRG.23703.2 ENSG00000113580 No_inf pgKDN_inf NR3C1 protein_coding   57.00864 78.94367 50.67097 2.100385 0.7727224 -0.6395623 17.640354 19.959640 19.374019 1.374059 0.9052545 -0.0429406 0.3218250 0.254675 0.381925 0.127250 0.180914269 0.003326334 FALSE TRUE
MSTRG.23703.3 ENSG00000113580 No_inf pgKDN_inf NR3C1 protein_coding   57.00864 78.94367 50.67097 2.100385 0.7727224 -0.6395623 28.094286 47.065200 21.437889 1.594229 0.4479918 -1.1341316 0.4667167 0.595825 0.423175 -0.172650 0.003326334 0.003326334 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000113580 E001 0.1271363 0.0123702382 8.980595e-01   5 143277931 143277933 3 - 0.000 0.077 9.538
ENSG00000113580 E002 0.8710761 0.0134075116 5.857337e-01 8.161141e-01 5 143277934 143277935 2 - 0.209 0.294 0.648
ENSG00000113580 E003 610.6836133 0.0001720295 3.130108e-29 1.758534e-26 5 143277936 143279411 1476 - 2.680 2.816 0.452
ENSG00000113580 E004 89.8479311 0.0002069259 1.175363e-04 2.716025e-03 5 143279412 143279566 155 - 1.856 1.986 0.438
ENSG00000113580 E005 598.6321541 0.0005212655 8.216191e-01 9.353299e-01 5 143279567 143281119 1553 - 2.760 2.764 0.012
ENSG00000113580 E006 17.8647563 0.0135083953 5.575717e-01 7.994520e-01 5 143281120 143281137 18 - 1.291 1.242 -0.171
ENSG00000113580 E007 18.8281251 0.0092151966 4.246862e-01 7.038821e-01 5 143281138 143281161 24 - 1.240 1.305 0.227
ENSG00000113580 E008 23.3635179 0.0010788767 7.989020e-01 9.244760e-01 5 143281162 143281181 20 - 1.361 1.378 0.059
ENSG00000113580 E009 176.4840654 0.0015528425 5.742489e-01 8.093327e-01 5 143281182 143281810 629 - 2.242 2.228 -0.047
ENSG00000113580 E010 88.1639788 0.0006663060 4.186405e-02 1.991167e-01 5 143281811 143282041 231 - 1.976 1.909 -0.227
ENSG00000113580 E011 58.0749451 0.0120045028 1.184716e-01 3.635621e-01 5 143282568 143282725 158 - 1.811 1.721 -0.305
ENSG00000113580 E012 26.3054657 0.0025257046 7.209118e-02 2.723186e-01 5 143295460 143295511 52 - 1.487 1.378 -0.376
ENSG00000113580 E013 38.4153246 0.0003828259 2.409835e-03 2.931217e-02 5 143295512 143295590 79 - 1.667 1.521 -0.499
ENSG00000113580 E014 56.0523158 0.0002596160 1.529823e-01 4.172700e-01 5 143298668 143298812 145 - 1.776 1.719 -0.194
ENSG00000113580 E015 30.7722324 0.0005086139 1.660174e-01 4.360804e-01 5 143300485 143300560 76 - 1.533 1.458 -0.256
ENSG00000113580 E016 22.5878342 0.0006067908 3.467788e-02 1.779728e-01 5 143300561 143300592 32 - 1.436 1.305 -0.454
ENSG00000113580 E017 32.0748036 0.0099592245 7.801121e-02 2.857507e-01 5 143300593 143300685 93 - 1.574 1.458 -0.397
ENSG00000113580 E018 34.6361960 0.0017385980 9.301585e-03 7.674182e-02 5 143300686 143300763 78 - 1.618 1.481 -0.469
ENSG00000113580 E019 38.7614675 0.0003602748 5.443271e-04 9.328802e-03 5 143310097 143310213 117 - 1.681 1.516 -0.564
ENSG00000113580 E020 1.5961547 0.0083720791 5.777654e-01 8.113163e-01 5 143313999 143314001 3 - 0.456 0.372 -0.452
ENSG00000113580 E021 41.6756205 0.0037973288 3.460275e-02 1.777564e-01 5 143314002 143314168 167 - 1.681 1.571 -0.375
ENSG00000113580 E022 0.4897584 0.0158885297 6.424778e-01   5 143389878 143390001 124 - 0.209 0.142 -0.674
ENSG00000113580 E023 36.2640758 0.0003798298 2.910117e-02 1.600594e-01 5 143399656 143399824 169 - 1.621 1.513 -0.370
ENSG00000113580 E024 22.8584000 0.0006431989 1.336431e-04 3.010823e-03 5 143399825 143399902 78 - 1.496 1.261 -0.813
ENSG00000113580 E025 86.4336302 0.0003118109 1.887414e-05 5.867194e-04 5 143399903 143400403 501 - 2.009 1.870 -0.469
ENSG00000113580 E026 12.1093379 0.0047393528 1.256690e-02 9.317621e-02 5 143400404 143400407 4 - 1.224 1.013 -0.762
ENSG00000113580 E027 70.3106137 0.0002185495 2.531860e-05 7.548552e-04 5 143400408 143400852 445 - 1.927 1.776 -0.508
ENSG00000113580 E028 0.5070043 0.0157274491 1.229547e-01 3.711141e-01 5 143401258 143401397 140 - 0.000 0.249 13.422
ENSG00000113580 E029 2.4679897 0.0060784244 8.912064e-01 9.637844e-01 5 143402602 143402753 152 - 0.541 0.522 -0.089
ENSG00000113580 E030 16.8245921 0.0040873975 1.264734e-01 3.769044e-01 5 143403211 143403720 510 - 1.305 1.191 -0.399
ENSG00000113580 E031 0.1170040 0.0117331984 3.298274e-01   5 143403785 143403985 201 - 0.117 0.000 -13.276
ENSG00000113580 E032 0.5968488 0.0150235111 6.123889e-02 2.485143e-01 5 143403986 143404129 144 - 0.350 0.077 -2.674
ENSG00000113580 E033 2.5924506 0.0052675302 9.709979e-01 9.943193e-01 5 143404376 143404544 169 - 0.541 0.546 0.026
ENSG00000113580 E034 0.0000000       5 143404619 143404667 49 -      
ENSG00000113580 E035 0.7617499 0.0132083183 3.831479e-02 1.889948e-01 5 143405150 143405323 174 - 0.000 0.335 14.023
ENSG00000113580 E036 0.1272623 0.0124171491 8.980233e-01   5 143408990 143409239 250 - 0.000 0.077 11.497
ENSG00000113580 E037 0.0000000       5 143433719 143433817 99 -      
ENSG00000113580 E038 0.0000000       5 143433818 143433827 10 -      
ENSG00000113580 E039 0.0000000       5 143434532 143435512 981 -      

Help

Please Click HERE to learn more details about the results from DEXseq.