ENSG00000113621

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358387 ENSG00000113621 No_inf pgKDN_inf TXNDC15 protein_coding protein_coding 23.35773 27.16855 17.33399 4.829868 1.112332 -0.6480321 9.087174 9.506001 9.2552328 0.3135390 0.3627902 -0.03852814 0.41940833 0.378525 0.540550 0.162025 0.46896751 0.01554842 FALSE TRUE
ENST00000505174 ENSG00000113621 No_inf pgKDN_inf TXNDC15 protein_coding retained_intron 23.35773 27.16855 17.33399 4.829868 1.112332 -0.6480321 1.256372 2.135381 0.6730343 0.3093261 0.1758359 -1.65120411 0.05589167 0.090500 0.038875 -0.051625 0.64806697 0.01554842 FALSE TRUE
ENST00000508779 ENSG00000113621 No_inf pgKDN_inf TXNDC15 protein_coding protein_coding 23.35773 27.16855 17.33399 4.829868 1.112332 -0.6480321 5.154060 3.184017 7.4057268 1.4252867 1.0874250 1.21521600 0.26251667 0.151425 0.420575 0.269150 0.32337505 0.01554842 FALSE TRUE
ENST00000509954 ENSG00000113621 No_inf pgKDN_inf TXNDC15 protein_coding protein_coding 23.35773 27.16855 17.33399 4.829868 1.112332 -0.6480321 6.013035 11.251843 0.0000000 5.9824770 0.0000000 -10.13722718 0.19040000 0.337925 0.000000 -0.337925 0.01554842 0.01554842 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000113621 E001 0.3532727 0.0157234304 0.0760598898   5 134874371 134874375 5 + 0.254 0.000 -11.074
ENSG00000113621 E002 1.3325999 0.0094943383 0.2468587396 0.537443154 5 134874376 134874396 21 + 0.456 0.280 -1.040
ENSG00000113621 E003 4.2623009 0.0032060648 0.1920762132 0.471891700 5 134874397 134874483 87 + 0.800 0.642 -0.647
ENSG00000113621 E004 5.8706652 0.0025149724 0.4052806023 0.688035307 5 134874484 134874530 47 + 0.883 0.792 -0.353
ENSG00000113621 E005 0.1271363 0.0123955833 0.6301523665   5 134875096 134875188 93 + 0.000 0.088 10.431
ENSG00000113621 E006 0.2352613 0.1954003812 0.2336726012   5 134875342 134875395 54 + 0.185 0.000 -12.241
ENSG00000113621 E007 5.4992927 0.0027070560 0.3313878568 0.623639980 5 134887695 134887700 6 + 0.867 0.759 -0.425
ENSG00000113621 E008 41.7689952 0.0003558182 0.0031327606 0.035638538 5 134887701 134888152 452 + 1.695 1.567 -0.435
ENSG00000113621 E009 7.5652844 0.0019363273 0.1674324659 0.438083340 5 134888153 134888182 30 + 1.001 0.865 -0.512
ENSG00000113621 E010 8.8581035 0.0020478251 0.0001171233 0.002707642 5 134892178 134893491 1314 + 0.741 1.120 1.435
ENSG00000113621 E011 20.4499608 0.0039452076 0.4487176109 0.722659250 5 134893492 134893625 134 + 1.357 1.305 -0.180
ENSG00000113621 E012 12.8548585 0.0011621451 0.4736296024 0.740641896 5 134893626 134893655 30 + 1.170 1.113 -0.205
ENSG00000113621 E013 0.1186381 0.0118770514 0.4583541624   5 134896021 134896293 273 + 0.102 0.000 -11.559
ENSG00000113621 E014 10.3723937 0.0013184617 0.1349763041 0.390589762 5 134896294 134896305 12 + 1.121 0.992 -0.471
ENSG00000113621 E015 26.4576172 0.0005239801 0.3893337880 0.675059402 5 134896306 134896424 119 + 1.409 1.456 0.159
ENSG00000113621 E016 52.4075262 0.0003493998 0.0080832104 0.069577303 5 134899489 134899936 448 + 1.666 1.766 0.338
ENSG00000113621 E017 15.0665947 0.0009264549 0.0881172899 0.307933393 5 134899937 134900154 218 + 1.129 1.254 0.442
ENSG00000113621 E018 43.6332757 0.0005615469 0.7746126213 0.913399006 5 134900155 134901065 911 + 1.641 1.651 0.037
ENSG00000113621 E019 19.1794527 0.0051650279 0.6631641992 0.859682680 5 134901066 134901635 570 + 1.286 1.315 0.102

Help

Please Click HERE to learn more details about the results from DEXseq.