ENSG00000113649

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296702 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding protein_coding 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 2.863130 0.4841911 1.7581410 0.4841911 1.7581410 1.8390924 0.05362500 0.012950 0.060975 0.048025 1.000000e+00 1.708613e-05 FALSE  
ENST00000394421 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding protein_coding 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 10.184002 8.5469926 13.8443095 0.6998152 1.3422107 0.6951591 0.22509167 0.198725 0.332850 0.134125 2.881075e-01 1.708613e-05 FALSE  
ENST00000505285 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding retained_intron 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 8.797623 3.6269820 10.6184338 2.1596389 4.1895209 1.5471153 0.15055833 0.091200 0.219075 0.127875 6.946737e-01 1.708613e-05 FALSE  
ENST00000506524 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding retained_intron 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 2.413077 3.2625348 1.9273020 0.2855515 0.2671182 -0.7563597 0.05410833 0.078000 0.050675 -0.027325 7.961351e-01 1.708613e-05 TRUE  
ENST00000509787 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding protein_coding_CDS_not_defined 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 1.762035 2.9044981 0.8050651 0.9629646 0.2702062 -1.8382603 0.04004167 0.073000 0.017475 -0.055525 4.692600e-01 1.708613e-05 FALSE  
ENST00000509810 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding retained_intron 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 2.413806 3.2711189 0.0000000 0.3861883 0.0000000 -8.3580441 0.04309167 0.078650 0.000000 -0.078650 1.708613e-05 1.708613e-05    
ENST00000613756 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding misc_RNA 54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 10.814230 7.9501606 0.0000000 7.9501606 0.0000000 -9.6366537 0.11623333 0.134150 0.000000 -0.134150 9.138717e-01 1.708613e-05    
MSTRG.23727.10 ENSG00000113649 No_inf pgKDN_inf TCERG1 protein_coding   54.61941 44.19314 42.71138 5.096301 5.842623 -0.04919083 5.752044 4.8534391 6.7563032 0.7881772 1.6440763 0.4763910 0.12580833 0.116650 0.152225 0.035575 8.343137e-01 1.708613e-05 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000113649 E001 0.0000000       5 146447311 146447311 1 +      
ENSG00000113649 E002 0.3645386 1.948101e-01 7.216843e-01   5 146447312 146447332 21 + 0.162 0.102 -0.779
ENSG00000113649 E003 1.6270610 5.348166e-02 3.728291e-02 0.1859101139 5 146447333 146447344 12 + 0.225 0.561 1.958
ENSG00000113649 E004 1.7440650 2.511625e-02 6.658556e-02 0.2599512243 5 146447345 146447345 1 + 0.280 0.561 1.543
ENSG00000113649 E005 6.7521647 2.234573e-03 3.335181e-01 0.6255608194 5 146447346 146447408 63 + 0.838 0.938 0.379
ENSG00000113649 E006 19.5556414 7.547324e-04 7.295902e-01 0.8922264547 5 146455056 146455281 226 + 1.302 1.324 0.077
ENSG00000113649 E007 14.8602384 2.423446e-02 5.186238e-01 0.7735683636 5 146457183 146457335 153 + 1.227 1.169 -0.208
ENSG00000113649 E008 15.9928974 1.242904e-02 5.428662e-02 0.2320227219 5 146458884 146459214 331 + 1.302 1.136 -0.586
ENSG00000113649 E009 12.0348329 3.040076e-03 1.874503e-01 0.4655741659 5 146459215 146459337 123 + 1.164 1.053 -0.400
ENSG00000113649 E010 0.6170484 1.596177e-02 5.379573e-01 0.7868468265 5 146462018 146462056 39 + 0.162 0.254 0.806
ENSG00000113649 E011 0.7360985 1.440813e-02 8.517529e-01 0.9475726798 5 146462057 146462096 40 + 0.225 0.254 0.221
ENSG00000113649 E012 21.6883199 7.015483e-04 3.006167e-03 0.0345408191 5 146463551 146463793 243 + 1.436 1.247 -0.660
ENSG00000113649 E013 1.3529050 1.193264e-01 6.236251e-01 0.8379467025 5 146468341 146468403 63 + 0.329 0.413 0.484
ENSG00000113649 E014 16.2934598 2.384864e-03 1.842348e-01 0.4613912685 5 146469544 146469744 201 + 1.282 1.184 -0.346
ENSG00000113649 E015 0.0000000       5 146469745 146469809 65 +      
ENSG00000113649 E016 4.5886731 4.475733e-02 6.722732e-02 0.2615150708 5 146470636 146470640 5 + 0.853 0.592 -1.075
ENSG00000113649 E017 12.2487939 5.868374e-03 6.750846e-02 0.2621544208 5 146470641 146470748 108 + 1.191 1.033 -0.569
ENSG00000113649 E018 9.7651152 1.480022e-02 9.831590e-01 0.9986902635 5 146471488 146471576 89 + 1.031 1.033 0.004
ENSG00000113649 E019 0.1170040 1.163376e-02 6.263819e-01   5 146478418 146478492 75 + 0.089 0.000 -10.670
ENSG00000113649 E020 7.5297168 3.850937e-02 4.630167e-01 0.7331076291 5 146478493 146478524 32 + 0.972 0.881 -0.344
ENSG00000113649 E021 18.0804543 3.066805e-02 7.441336e-01 0.8987349350 5 146478525 146478653 129 + 1.266 1.296 0.105
ENSG00000113649 E022 14.1547678 2.416968e-02 8.904900e-01 0.9635021202 5 146479855 146479911 57 + 1.177 1.184 0.023
ENSG00000113649 E023 14.4923577 1.103374e-02 5.359634e-01 0.7853601226 5 146480028 146480094 67 + 1.215 1.161 -0.194
ENSG00000113649 E024 5.8073263 2.577645e-03 3.433609e-02 0.1769427404 5 146480095 146480518 424 + 0.706 0.938 0.909
ENSG00000113649 E025 1.8374346 7.878272e-03 5.798563e-01 0.8124375363 5 146481150 146481175 26 + 0.413 0.493 0.414
ENSG00000113649 E026 1.6030183 8.305384e-03 2.705193e-01 0.5642208397 5 146481176 146481200 25 + 0.329 0.493 0.899
ENSG00000113649 E027 17.5889699 7.923852e-04 3.638021e-06 0.0001427004 5 146481201 146482591 1391 + 1.083 1.408 1.146
ENSG00000113649 E028 17.5121146 8.782190e-04 2.141048e-01 0.4993094163 5 146482592 146482727 136 + 1.307 1.220 -0.306
ENSG00000113649 E029 18.2432273 8.379024e-04 2.382295e-01 0.5270967970 5 146483540 146483629 90 + 1.321 1.240 -0.284
ENSG00000113649 E030 0.1268540 1.230801e-02 4.611850e-01   5 146492869 146492919 51 + 0.000 0.102 10.144
ENSG00000113649 E031 29.5005361 4.651952e-04 4.616182e-01 0.7322333536 5 146492920 146493038 119 + 1.503 1.463 -0.138
ENSG00000113649 E032 34.1625702 8.269353e-04 7.014979e-01 0.8784033637 5 146498536 146498678 143 + 1.555 1.535 -0.068
ENSG00000113649 E033 14.0769778 1.373511e-03 5.012178e-02 0.2211262255 5 146498679 146498686 8 + 1.244 1.092 -0.542
ENSG00000113649 E034 2.9760632 2.452754e-02 5.921772e-02 0.2442479731 5 146499573 146499971 399 + 0.449 0.718 1.221
ENSG00000113649 E035 4.2526783 5.847481e-03 9.537522e-05 0.0022879153 5 146503032 146503374 343 + 0.413 0.910 2.169
ENSG00000113649 E036 19.4481416 7.505649e-04 8.473191e-02 0.3007641456 5 146503375 146503418 44 + 1.362 1.247 -0.402
ENSG00000113649 E037 23.3442423 6.302587e-04 9.133367e-02 0.3139573183 5 146503419 146503470 52 + 1.433 1.329 -0.358
ENSG00000113649 E038 21.6872546 1.322307e-02 5.116506e-01 0.7687800807 5 146503471 146503539 69 + 1.378 1.329 -0.170
ENSG00000113649 E039 10.2801497 1.439417e-03 6.268826e-01 0.8397775853 5 146503824 146503827 4 + 1.031 1.073 0.152
ENSG00000113649 E040 33.9450335 1.009202e-02 9.418212e-01 0.9836052783 5 146503828 146504006 179 + 1.544 1.542 -0.008
ENSG00000113649 E041 0.4982540 1.521109e-02 2.506275e-01   5 146504007 146504202 196 + 0.089 0.254 1.806
ENSG00000113649 E042 0.3621152 2.192868e-01 7.295246e-01   5 146504364 146504494 131 + 0.162 0.102 -0.778
ENSG00000113649 E043 0.1170040 1.163376e-02 6.263819e-01   5 146505505 146505621 117 + 0.089 0.000 -10.670
ENSG00000113649 E044 37.8365300 4.213413e-04 8.143068e-01 0.9321424297 5 146507028 146507207 180 + 1.595 1.583 -0.040
ENSG00000113649 E045 0.7509211 3.340949e-01 1.787126e-01 0.4536492958 5 146507208 146507348 141 + 0.089 0.366 2.542
ENSG00000113649 E046 2.8681219 2.899972e-02 1.246763e-02 0.0926391960 5 146507371 146507744 374 + 0.373 0.740 1.723
ENSG00000113649 E047 0.3712766 2.256793e-01 5.426033e-01   5 146507745 146507778 34 + 0.089 0.184 1.222
ENSG00000113649 E048 0.9859053 1.172183e-02 3.572343e-01 0.6468500645 5 146507779 146507872 94 + 0.225 0.366 0.958
ENSG00000113649 E049 23.8014435 1.155088e-03 9.937800e-01 1.0000000000 5 146507873 146507956 84 + 1.395 1.394 -0.001
ENSG00000113649 E050 26.1870207 1.224377e-03 3.236629e-01 0.6163343107 5 146509145 146509245 101 + 1.406 1.463 0.194
ENSG00000113649 E051 4.5582719 1.181792e-02 1.208892e-01 0.3678443089 5 146510067 146510115 49 + 0.643 0.833 0.774
ENSG00000113649 E052 4.3155843 3.229342e-03 1.036828e-01 0.3365485436 5 146510116 146510160 45 + 0.621 0.816 0.806
ENSG00000113649 E053 0.4978483 2.413010e-02 2.524429e-01   5 146510161 146510271 111 + 0.089 0.254 1.806
ENSG00000113649 E054 177.6142542 9.918689e-05 3.647112e-02 0.1837147308 5 146510441 146511961 1521 + 2.231 2.273 0.138

Help

Please Click HERE to learn more details about the results from DEXseq.