ENSG00000113657

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398514 ENSG00000113657 No_inf pgKDN_inf DPYSL3 protein_coding protein_coding 3.287144 0.7995753 4.840863 0.0486642 0.6363225 2.583004 1.5563713 0.7995753 1.8193732 0.0486642 0.1278075 1.176112 0.66112500 1 0.387575 -0.612425 0.00346786 0.00346786 FALSE TRUE
ENST00000507309 ENSG00000113657 No_inf pgKDN_inf DPYSL3 protein_coding protein_coding_CDS_not_defined 3.287144 0.7995753 4.840863 0.0486642 0.6363225 2.583004 0.3390690 0.0000000 1.0172071 0.0000000 1.0172071 6.682583 0.05541667 0 0.166250 0.166250 1.00000000 0.00346786 FALSE FALSE
ENST00000512722 ENSG00000113657 No_inf pgKDN_inf DPYSL3 protein_coding protein_coding 3.287144 0.7995753 4.840863 0.0486642 0.6363225 2.583004 0.1387690 0.0000000 0.4163070 0.0000000 0.4163070 5.413821 0.04443333 0 0.133300 0.133300 1.00000000 0.00346786 TRUE FALSE
ENST00000520473 ENSG00000113657 No_inf pgKDN_inf DPYSL3 protein_coding protein_coding 3.287144 0.7995753 4.840863 0.0486642 0.6363225 2.583004 0.5701521 0.0000000 0.7082062 0.0000000 0.7082062 6.166326 0.12519167 0 0.148750 0.148750 1.00000000 0.00346786 FALSE TRUE
ENST00000523458 ENSG00000113657 No_inf pgKDN_inf DPYSL3 protein_coding nonsense_mediated_decay 3.287144 0.7995753 4.840863 0.0486642 0.6363225 2.583004 0.5657956 0.0000000 0.8797691 0.0000000 0.8797691 6.475359 0.09160833 0 0.164125 0.164125 1.00000000 0.00346786 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000113657 E001 0.0000000       5 147390808 147390810 3 -      
ENSG00000113657 E002 19.3208206 0.001130970 4.738227e-05 0.001276375 5 147390811 147393824 3014 - 1.219 1.383 0.571
ENSG00000113657 E003 5.1991250 0.040361008 6.666455e-01 0.861342994 5 147393825 147394123 299 - 0.765 0.767 0.009
ENSG00000113657 E004 1.3366583 0.097924154 5.579394e-01 0.799684480 5 147395559 147395653 95 - 0.327 0.397 0.408
ENSG00000113657 E005 0.3631227 0.016949959 7.958329e-01   5 147395654 147395676 23 - 0.121 0.138 0.217
ENSG00000113657 E006 0.8464295 0.013489821 9.570690e-01 0.989752447 5 147395677 147395721 45 - 0.256 0.242 -0.105
ENSG00000113657 E007 2.3989057 0.008518238 4.227945e-01 0.702062729 5 147397666 147397845 180 - 0.553 0.397 -0.784
ENSG00000113657 E008 2.7519186 0.006319836 2.404825e-01 0.529719622 5 147399082 147399252 171 - 0.608 0.397 -1.031
ENSG00000113657 E009 1.9061556 0.034124385 1.466248e-01 0.407673958 5 147400692 147400833 142 - 0.512 0.242 -1.591
ENSG00000113657 E010 2.3678668 0.006774936 7.821582e-03 0.068073132 5 147401540 147401696 157 - 0.608 0.138 -3.031
ENSG00000113657 E011 1.1814738 0.013801512 2.567575e-02 0.147995718 5 147405610 147405641 32 - 0.416 0.000 -14.249
ENSG00000113657 E012 1.4368190 0.010571359 3.689959e-01 0.657441882 5 147405642 147405730 89 - 0.416 0.242 -1.105
ENSG00000113657 E013 0.0000000       5 147405731 147406198 468 -      
ENSG00000113657 E014 0.7276003 0.014325001 7.617489e-01 0.907078710 5 147408728 147408796 69 - 0.215 0.242 0.217
ENSG00000113657 E015 0.8524706 0.014121792 3.905668e-01 0.676126567 5 147412608 147412688 81 - 0.215 0.326 0.801
ENSG00000113657 E016 0.6147850 0.019345148 1.346991e-01 0.390164397 5 147413596 147413657 62 - 0.121 0.326 1.802
ENSG00000113657 E017 1.5621378 0.009590558 6.992750e-01 0.877449843 5 147415709 147415873 165 - 0.416 0.326 -0.520
ENSG00000113657 E018 0.1176306 0.012037389 1.000000e+00   5 147418447 147418477 31 - 0.065 0.000 -11.379
ENSG00000113657 E019 0.1176306 0.012037389 1.000000e+00   5 147418478 147418482 5 - 0.065 0.000 -11.379
ENSG00000113657 E020 1.3092196 0.011128327 1.268126e-01 0.377456339 5 147418483 147418631 149 - 0.416 0.138 -2.105
ENSG00000113657 E021 0.9456510 0.011887044 5.370764e-02 0.230699910 5 147424875 147424963 89 - 0.359 0.000 -13.978
ENSG00000113657 E022 0.3539644 0.019015840 4.661186e-01   5 147453549 147453593 45 - 0.171 0.000 -12.781
ENSG00000113657 E023 0.4726676 0.020436959 2.895795e-01   5 147453594 147453754 161 - 0.215 0.000 -13.134
ENSG00000113657 E024 0.1187032 0.012154422 1.000000e+00   5 147453755 147453959 205 - 0.065 0.000 -11.379
ENSG00000113657 E025 0.2346346 0.016607538 8.174855e-01   5 147454172 147454266 95 - 0.121 0.000 -12.274
ENSG00000113657 E026 0.0000000       5 147472632 147473344 713 -      
ENSG00000113657 E027 0.0000000       5 147509478 147510068 591 -      

Help

Please Click HERE to learn more details about the results from DEXseq.