ENSG00000113742

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265085 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 2.4617698 1.4713028 3.0255086 0.1659501 0.2291662 1.035072 0.48335833 0.334425 0.549000 0.214575 0.56058914 0.04906564 FALSE TRUE
ENST00000517880 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.3758958 0.0000000 1.1276873 0.0000000 0.6622145 6.829960 0.06655833 0.000000 0.199675 0.199675 0.50792018 0.04906564 FALSE TRUE
ENST00000519152 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.2535638 0.7606914 0.0000000 0.7606914 0.0000000 -6.268081 0.03709167 0.111275 0.000000 -0.111275 0.83517651 0.04906564 FALSE FALSE
ENST00000519467 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.1472851 0.0000000 0.4418552 0.0000000 0.4418552 5.497789 0.02723333 0.000000 0.081700 0.081700 0.85166479 0.04906564 FALSE TRUE
ENST00000520867 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.6184859 0.3005183 0.9381256 0.3005183 0.5850839 1.610400 0.11835833 0.043975 0.169625 0.125650 0.82735696 0.04906564 FALSE TRUE
ENST00000522336 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.4164131 0.5418500 0.0000000 0.5418500 0.0000000 -5.786204 0.09800000 0.149125 0.000000 -0.149125 0.85166202 0.04906564 FALSE TRUE
ENST00000657000 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding protein_coding 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.5932631 1.4304286 0.0000000 0.5088128 0.0000000 -7.170354 0.11974167 0.297525 0.000000 -0.297525 0.04906564 0.04906564 FALSE TRUE
ENST00000659882 ENSG00000113742 No_inf pgKDN_inf CPEB4 protein_coding nonsense_mediated_decay 5.122703 4.81336 5.533177 0.7216845 0.1017125 0.2006744 0.1028564 0.3085691 0.0000000 0.3085691 0.0000000 -4.993535 0.02122500 0.063675 0.000000 -0.063675 0.83668872 0.04906564   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000113742 E001 10.7194604 0.0014442553 0.006802265 0.06190910 5 173888349 173889339 991 + 1.153 0.917 -0.864
ENSG00000113742 E002 3.4026878 0.0123134689 0.789010252 0.91898413 5 173889340 173889530 191 + 0.654 0.623 -0.136
ENSG00000113742 E003 16.0358865 0.0008697322 0.452614950 0.72574592 5 173889531 173890665 1135 + 1.248 1.199 -0.176
ENSG00000113742 E004 1.3420409 0.0101380381 0.807317323 0.92887002 5 173890666 173890673 8 + 0.350 0.389 0.229
ENSG00000113742 E005 1.3420409 0.0101380381 0.807317323 0.92887002 5 173890674 173890676 3 + 0.350 0.389 0.229
ENSG00000113742 E006 4.9541773 0.0034943962 0.186341729 0.46427226 5 173890677 173890858 182 + 0.831 0.679 -0.615
ENSG00000113742 E007 0.1268540 0.0123294968 0.382430327   5 173891372 173891607 236 + 0.000 0.111 11.784
ENSG00000113742 E008 0.0000000       5 173893051 173893077 27 +      
ENSG00000113742 E009 0.0000000       5 173893078 173893183 106 +      
ENSG00000113742 E010 2.5511565 0.0864446538 0.703020737 0.87919127 5 173910523 173910604 82 + 0.566 0.521 -0.208
ENSG00000113742 E011 0.0000000       5 173910605 173910818 214 +      
ENSG00000113742 E012 0.0000000       5 173918201 173918215 15 +      
ENSG00000113742 E013 0.0000000       5 173918216 173918254 39 +      
ENSG00000113742 E014 0.8887913 0.0127991868 0.001143913 0.01660795 5 173932450 173932500 51 + 0.000 0.482 14.380
ENSG00000113742 E015 0.1271363 0.0124177687 0.382275723   5 173942884 173943025 142 + 0.000 0.111 11.784
ENSG00000113742 E016 0.1271363 0.0124177687 0.382275723   5 173943026 173943049 24 + 0.000 0.111 11.784
ENSG00000113742 E017 3.9901175 0.0124304653 0.338600784 0.63027074 5 173944967 173945140 174 + 0.744 0.622 -0.508
ENSG00000113742 E018 2.6601380 0.0609527789 0.670214623 0.86300799 5 173949508 173949597 90 + 0.590 0.521 -0.315
ENSG00000113742 E019 0.0000000       5 173949880 173949959 80 +      
ENSG00000113742 E020 2.4324545 0.0056089730 0.873741107 0.95691722 5 173949960 173950078 119 + 0.541 0.521 -0.093
ENSG00000113742 E021 3.0059255 0.0158877511 0.072754066 0.27399747 5 173951824 173951938 115 + 0.692 0.438 -1.171
ENSG00000113742 E022 5.9346318 0.1172353904 0.537732902 0.78673194 5 173953091 173953272 182 + 0.881 0.773 -0.422
ENSG00000113742 E023 0.0000000       5 173953273 173953439 167 +      
ENSG00000113742 E024 150.2169764 0.0001790437 0.003039788 0.03486770 5 173955910 173961980 6071 + 2.157 2.200 0.144

Help

Please Click HERE to learn more details about the results from DEXseq.