ENSG00000114353

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313601 ENSG00000114353 No_inf pgKDN_inf GNAI2 protein_coding protein_coding 248.8802 220.5424 270.7495 2.378961 3.707554 0.2958902 225.75856 188.69260 252.62816 1.841373 4.6657736 0.4209583 0.90436667 0.856050 0.932925 0.076875 0.0002826567 0.0002826567 FALSE  
ENST00000492383 ENSG00000114353 No_inf pgKDN_inf GNAI2 protein_coding retained_intron 248.8802 220.5424 270.7495 2.378961 3.707554 0.2958902 16.38398 19.49883 15.08977 1.924179 0.8180478 -0.3696011 0.06703333 0.088225 0.055850 -0.032375 0.3512619485 0.0002826567 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000114353 E001 0.0000000       3 50226292 50226736 445 +      
ENSG00000114353 E002 0.1186381 1.172338e-02 6.215451e-01   3 50226737 50227193 457 + 0.089 0.000 -8.353
ENSG00000114353 E003 0.7341784 1.344947e-02 8.593421e-01 9.509963e-01 3 50229065 50230775 1711 + 0.226 0.253 0.213
ENSG00000114353 E004 0.4914576 1.609838e-02 8.847491e-01   3 50230776 50230809 34 + 0.163 0.184 0.213
ENSG00000114353 E005 0.4913316 1.610620e-02 8.846470e-01   3 50230810 50230998 189 + 0.163 0.184 0.213
ENSG00000114353 E006 0.1170040 1.164332e-02 6.215053e-01   3 50235196 50235290 95 + 0.089 0.000 -10.146
ENSG00000114353 E007 159.2965425 1.148200e-04 2.353576e-03 2.882329e-02 3 50236204 50236453 250 + 2.238 2.166 -0.240
ENSG00000114353 E008 2.2422929 6.189339e-03 2.812044e-02 1.567595e-01 3 50238112 50238416 305 + 0.330 0.646 1.592
ENSG00000114353 E009 0.7520563 3.294530e-01 1.801307e-01 4.555551e-01 3 50246894 50247075 182 + 0.089 0.365 2.536
ENSG00000114353 E010 1.2612937 9.760169e-03 3.822940e-03 4.118531e-02 3 50251409 50251619 211 + 0.089 0.528 3.383
ENSG00000114353 E011 0.8798238 1.235305e-02 3.196295e-02 1.690204e-01 3 50251620 50251743 124 + 0.089 0.412 2.798
ENSG00000114353 E012 1.7497654 7.925800e-03 1.472843e-02 1.037434e-01 3 50251744 50252099 356 + 0.226 0.591 2.088
ENSG00000114353 E013 159.3831740 1.407420e-04 1.401760e-04 3.129243e-03 3 50252100 50252142 43 + 2.246 2.155 -0.303
ENSG00000114353 E014 1.2051468 1.033464e-02 2.971884e-01 5.903584e-01 3 50252143 50252396 254 + 0.414 0.253 -1.009
ENSG00000114353 E015 272.0816916 6.368392e-04 8.083248e-05 1.988877e-03 3 50252397 50252538 142 + 2.472 2.393 -0.265
ENSG00000114353 E016 213.7498528 9.476528e-05 5.077186e-01 7.660887e-01 3 50253024 50253153 130 + 2.338 2.325 -0.043
ENSG00000114353 E017 117.9481433 1.690253e-04 2.664573e-01 5.599060e-01 3 50253154 50253184 31 + 2.089 2.059 -0.101
ENSG00000114353 E018 151.2883102 1.250266e-04 3.668456e-01 6.555658e-01 3 50256192 50256282 91 + 2.193 2.171 -0.071
ENSG00000114353 E019 89.9254243 2.431055e-04 1.220244e-01 3.695715e-01 3 50256283 50256320 38 + 1.981 1.932 -0.164
ENSG00000114353 E020 7.2897745 4.941896e-03 7.359117e-10 6.474823e-08 3 50256321 50256691 371 + 0.450 1.152 2.857
ENSG00000114353 E021 206.5032506 1.238247e-04 8.916755e-01 9.640111e-01 3 50256723 50256852 130 + 2.318 2.316 -0.007
ENSG00000114353 E022 260.5589240 3.667037e-04 1.554478e-01 4.213026e-01 3 50256937 50257090 154 + 2.430 2.403 -0.090
ENSG00000114353 E023 346.3668619 6.367502e-04 4.527616e-01 7.257500e-01 3 50257500 50257714 215 + 2.533 2.548 0.048
ENSG00000114353 E024 43.2409136 4.057808e-03 1.979550e-04 4.146215e-03 3 50257715 50258166 452 + 1.540 1.736 0.669
ENSG00000114353 E025 1166.9436001 6.435745e-05 2.623106e-08 1.728404e-06 3 50258368 50259362 995 + 3.046 3.088 0.140

Help

Please Click HERE to learn more details about the results from DEXseq.