ENSG00000114520

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000251775 ENSG00000114520 No_inf pgKDN_inf SNX4 protein_coding protein_coding 27.507 22.87777 33.59125 0.6365358 1.83193 0.5539383 20.767731 20.1438261 21.839678 1.1135876 0.8893597 0.1165583 0.78267500 0.886375 0.660250 -0.226125 4.510239e-01 5.477492e-09 FALSE TRUE
ENST00000471751 ENSG00000114520 No_inf pgKDN_inf SNX4 protein_coding nonsense_mediated_decay 27.507 22.87777 33.59125 0.6365358 1.83193 0.5539383 2.439117 0.0000000 7.317352 0.0000000 1.3027316 9.5171481 0.07220833 0.000000 0.216625 0.216625 5.477492e-09 5.477492e-09 FALSE TRUE
ENST00000482965 ENSG00000114520 No_inf pgKDN_inf SNX4 protein_coding protein_coding_CDS_not_defined 27.507 22.87777 33.59125 0.6365358 1.83193 0.5539383 2.143853 1.8185261 0.000000 1.8185261 0.0000000 -7.5145374 0.07612500 0.073950 0.000000 -0.073950 8.336667e-01 5.477492e-09 FALSE TRUE
MSTRG.20635.5 ENSG00000114520 No_inf pgKDN_inf SNX4 protein_coding   27.507 22.87777 33.59125 0.6365358 1.83193 0.5539383 2.156303 0.9154136 4.434222 0.9154136 2.1365123 2.2637605 0.06899167 0.039675 0.123100 0.083425 4.403536e-01 5.477492e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000114520 E001 99.4015472 0.0002009785 7.759068e-06 0.0002742317 3 125446650 125447710 1061 - 1.940 2.060 0.403
ENSG00000114520 E002 25.8981726 0.0006025793 1.127136e-01 0.3531689782 3 125447711 125447826 116 - 1.469 1.380 -0.309
ENSG00000114520 E003 0.1265070 0.0124028670 4.513648e-01   3 125449070 125449255 186 - 0.000 0.103 10.499
ENSG00000114520 E004 32.4826460 0.0005328304 1.012241e-01 0.3322515619 3 125451305 125451419 115 - 1.561 1.479 -0.283
ENSG00000114520 E005 38.4007247 0.0004038504 4.912614e-01 0.7535534264 3 125453810 125453955 146 - 1.609 1.578 -0.106
ENSG00000114520 E006 26.3397234 0.0018354903 7.238055e-01 0.8890568097 3 125457266 125457365 100 - 1.446 1.426 -0.069
ENSG00000114520 E007 17.7578022 0.0014474268 1.483397e-01 0.4101376719 3 125460771 125460860 90 - 1.317 1.217 -0.348
ENSG00000114520 E008 0.1272623 0.0122795140 4.516511e-01   3 125469444 125469453 10 - 0.000 0.103 10.500
ENSG00000114520 E009 14.4073617 0.0110663281 8.529544e-01 0.9481490421 3 125469454 125469519 66 - 1.192 1.181 -0.041
ENSG00000114520 E010 1.3211794 0.0125757243 2.170337e-01 0.5032888975 3 125470583 125470661 79 - 0.446 0.256 -1.162
ENSG00000114520 E011 15.7399660 0.0012396589 8.700232e-01 0.9552119508 3 125476695 125476756 62 - 1.228 1.217 -0.039
ENSG00000114520 E012 15.5537762 0.0010017454 1.295855e-01 0.3818915156 3 125480247 125480319 73 - 1.267 1.157 -0.388
ENSG00000114520 E013 14.8294554 0.0012097645 2.200942e-01 0.5068773589 3 125489408 125489463 56 - 1.240 1.149 -0.322
ENSG00000114520 E014 13.4882265 0.0010589404 1.986150e-01 0.4800285053 3 125497341 125497388 48 - 1.205 1.106 -0.354
ENSG00000114520 E015 27.9114969 0.0028606503 5.541457e-01 0.7970157798 3 125497834 125497983 150 - 1.476 1.443 -0.114
ENSG00000114520 E016 26.3146502 0.0043243427 2.614910e-01 0.5542208168 3 125498059 125498194 136 - 1.402 1.471 0.240
ENSG00000114520 E017 21.5418496 0.0025230014 4.123810e-01 0.6936550933 3 125504623 125504744 122 - 1.326 1.380 0.188
ENSG00000114520 E018 14.6497476 0.0010313312 9.723213e-01 0.9947660217 3 125520032 125520202 171 - 1.192 1.196 0.012

Help

Please Click HERE to learn more details about the results from DEXseq.