ENSG00000114650

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265565 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding protein_coding 26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 4.3600523 1.704387 5.796722 1.0384414 3.113374 1.76003118 0.16899167 0.066250 0.238400 0.172150 0.731502954 0.001118902 FALSE  
ENST00000320017 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding nonsense_mediated_decay 26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 3.1742921 2.369765 5.154129 1.3971105 1.738328 1.11770627 0.12062500 0.090925 0.195875 0.104950 0.757702572 0.001118902 FALSE  
ENST00000441517 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding nonsense_mediated_decay 26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 1.8430880 1.418441 1.118510 1.0358403 1.118510 -0.34002217 0.06862500 0.053125 0.047850 -0.005275 0.836372532 0.001118902 FALSE  
ENST00000468965 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding retained_intron 26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 0.9417503 2.016470 0.000000 0.5595663 0.000000 -7.66282523 0.03489167 0.075600 0.000000 -0.075600 0.001118902 0.001118902 FALSE  
MSTRG.20089.2 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding   26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 4.8152668 2.597089 3.188871 1.5942887 3.188871 0.29512329 0.18220833 0.102700 0.121125 0.018425 0.828182219 0.001118902 FALSE  
MSTRG.20089.3 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding   26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 4.4810063 4.549013 4.853312 2.6266836 2.951329 0.09321752 0.16961667 0.183475 0.188300 0.004825 1.000000000 0.001118902 FALSE  
MSTRG.20089.4 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding   26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 1.9622530 2.218615 3.285563 1.6694926 3.285563 0.56437722 0.07110000 0.078125 0.120800 0.042675 0.834401793 0.001118902 TRUE  
MSTRG.20089.8 ENSG00000114650 No_inf pgKDN_inf SCAP protein_coding   26.50973 26.23496 25.58755 1.084382 0.818554 -0.03603468 3.3281909 6.089267 1.105326 1.8884152 1.105326 -2.45117113 0.12369167 0.226175 0.047275 -0.178900 0.094376556 0.001118902 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000114650 E001 0.4906372 0.1018422239 0.8953374540   3 47413681 47413709 29 - 0.163 0.184 0.219
ENSG00000114650 E002 0.1265070 0.0122903710 0.4706939985   3 47413710 47413712 3 - 0.000 0.102 12.100
ENSG00000114650 E003 0.5974104 0.0152786654 0.2234341101 0.511077454 3 47413713 47413735 23 - 0.280 0.102 -1.781
ENSG00000114650 E004 1.8137929 0.0125034990 0.3047738499 0.598083476 3 47413736 47413746 11 - 0.514 0.366 -0.781
ENSG00000114650 E005 57.8795825 0.0055449251 0.3796876382 0.666321969 3 47413747 47414099 353 - 1.746 1.794 0.165
ENSG00000114650 E006 52.9247243 0.0066526391 0.0134491114 0.097455915 3 47414180 47414386 207 - 1.662 1.796 0.455
ENSG00000114650 E007 22.5596026 0.0048906591 0.2679417488 0.561450339 3 47414572 47414652 81 - 1.331 1.412 0.282
ENSG00000114650 E008 41.8221847 0.0059717539 0.0068301186 0.062047434 3 47414827 47414993 167 - 1.550 1.705 0.526
ENSG00000114650 E009 24.9069567 0.0006457855 0.8686923553 0.954870650 3 47415098 47415180 83 - 1.414 1.412 -0.007
ENSG00000114650 E010 26.6849838 0.0061726654 0.3871173213 0.673030643 3 47417122 47417207 86 - 1.410 1.474 0.219
ENSG00000114650 E011 72.5050145 0.0012914069 0.4687259287 0.736864362 3 47417304 47417823 520 - 1.875 1.856 -0.063
ENSG00000114650 E012 1.7011423 0.1571025236 0.8482506146 0.946285748 3 47417824 47417826 3 - 0.449 0.412 -0.194
ENSG00000114650 E013 16.4152848 0.0118309730 0.4265212357 0.705060114 3 47418134 47418249 116 - 1.203 1.278 0.262
ENSG00000114650 E014 19.6549792 0.0026062491 0.8668743075 0.954124299 3 47418321 47418522 202 - 1.317 1.313 -0.014
ENSG00000114650 E015 17.6438630 0.0010552732 0.4224221597 0.701725345 3 47418655 47418843 189 - 1.239 1.301 0.219
ENSG00000114650 E016 13.0203533 0.0197912148 0.3462354871 0.637082652 3 47419328 47419384 57 - 1.184 1.101 -0.298
ENSG00000114650 E017 12.0447460 0.0041388869 0.3153003602 0.608226676 3 47419385 47419425 41 - 1.151 1.073 -0.281
ENSG00000114650 E018 31.4879194 0.0064632275 0.7253919826 0.889823352 3 47419426 47419704 279 - 1.518 1.504 -0.050
ENSG00000114650 E019 15.3786670 0.0021999142 0.6321569321 0.842365707 3 47420554 47420618 65 - 1.227 1.198 -0.103
ENSG00000114650 E020 13.8678036 0.0175327560 0.2259935768 0.513909691 3 47420619 47420653 35 - 1.222 1.110 -0.398
ENSG00000114650 E021 24.9611515 0.0107116836 0.2208454033 0.507826731 3 47420654 47420772 119 - 1.451 1.370 -0.278
ENSG00000114650 E022 19.1621102 0.0189974024 0.6543134029 0.854874487 3 47420931 47421029 99 - 1.317 1.290 -0.095
ENSG00000114650 E023 1.0071462 0.0862964891 0.0257297737 0.148164597 3 47421030 47421365 336 - 0.089 0.455 3.027
ENSG00000114650 E024 15.2561153 0.0179585403 0.8370646695 0.941606096 3 47422442 47422536 95 - 1.216 1.206 -0.035
ENSG00000114650 E025 1.5227143 0.0095799368 0.0000495988 0.001320366 3 47422537 47422793 257 - 0.000 0.620 15.436
ENSG00000114650 E026 16.1360020 0.0011947248 0.0359028093 0.181768714 3 47423933 47424045 113 - 1.297 1.152 -0.512
ENSG00000114650 E027 0.6341407 0.0151245058 0.0138985544 0.099522654 3 47424046 47424121 76 - 0.000 0.366 14.288
ENSG00000114650 E028 0.7349036 0.0144133659 0.8716153908 0.955928676 3 47425275 47425484 210 - 0.225 0.253 0.219
ENSG00000114650 E029 14.2635036 0.0035935975 0.5204434412 0.774761153 3 47425485 47425611 127 - 1.203 1.160 -0.153
ENSG00000114650 E030 16.8297487 0.0008546216 0.0021877718 0.027301083 3 47425997 47426169 173 - 1.340 1.128 -0.750
ENSG00000114650 E031 8.3859698 0.0066370858 0.2291160099 0.517793266 3 47427157 47427262 106 - 1.022 0.910 -0.418
ENSG00000114650 E032 16.8333903 0.0096067160 0.6197865824 0.835491168 3 47427447 47427638 192 - 1.266 1.233 -0.117
ENSG00000114650 E033 8.0935667 0.0148544217 0.0223353659 0.135932704 3 47427639 47427667 29 - 1.058 0.816 -0.912
ENSG00000114650 E034 6.7561178 0.0083276279 0.0085858989 0.072536321 3 47428513 47428525 13 - 1.003 0.718 -1.103
ENSG00000114650 E035 8.9767536 0.0090388540 0.1007798084 0.331369761 3 47428526 47428560 35 - 1.067 0.910 -0.580
ENSG00000114650 E036 16.5534937 0.0015885445 0.3027589049 0.595891999 3 47428561 47428670 110 - 1.203 1.284 0.284
ENSG00000114650 E037 0.6165451 0.0190716542 0.5537527075 0.796811764 3 47428671 47429026 356 - 0.162 0.253 0.804
ENSG00000114650 E038 0.0000000       3 47434853 47434924 72 -      
ENSG00000114650 E039 0.3806233 0.0158452125 0.0797934153   3 47434925 47434995 71 - 0.000 0.253 13.603
ENSG00000114650 E040 0.0000000       3 47434996 47435007 12 -      
ENSG00000114650 E041 14.4680922 0.0010650087 0.2739077955 0.567632719 3 47435008 47435137 130 - 1.144 1.233 0.317
ENSG00000114650 E042 16.1412658 0.0022568355 0.6839557126 0.869231352 3 47442872 47443091 220 - 1.216 1.253 0.132
ENSG00000114650 E043 0.0000000       3 47443092 47443302 211 -      
ENSG00000114650 E044 0.1265070 0.0122903710 0.4706939985   3 47466376 47466447 72 - 0.000 0.102 12.100
ENSG00000114650 E045 0.0000000       3 47468053 47468101 49 -      
ENSG00000114650 E046 0.2545247 0.2716396737 0.2552146066   3 47472771 47472830 60 - 0.000 0.184 12.446
ENSG00000114650 E047 0.0000000       3 47475423 47475798 376 -      
ENSG00000114650 E048 3.9958166 0.0059397654 0.1278672324 0.379059488 3 47475799 47475978 180 - 0.777 0.592 -0.781
ENSG00000114650 E049 0.0000000       3 47476939 47477126 188 -      

Help

Please Click HERE to learn more details about the results from DEXseq.