ENSG00000114942

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000392221 ENSG00000114942 No_inf pgKDN_inf EEF1B2 protein_coding protein_coding 808.3897 582.4534 1031.985 9.005617 16.01814 0.8251964 114.3529 54.22038 151.6751 3.728653 8.724173 1.4839062 0.1363333 0.093150 0.146800 0.053650 0.01151626 0.01151626 FALSE  
ENST00000392222 ENSG00000114942 No_inf pgKDN_inf EEF1B2 protein_coding protein_coding 808.3897 582.4534 1031.985 9.005617 16.01814 0.8251964 560.7367 397.78710 696.2397 7.565090 10.521559 0.8075721 0.6944250 0.682900 0.675175 -0.007725 0.92260425 0.01151626 FALSE  
MSTRG.17536.11 ENSG00000114942 No_inf pgKDN_inf EEF1B2 protein_coding   808.3897 582.4534 1031.985 9.005617 16.01814 0.8251964 101.7175 112.95853 140.1411 5.236535 9.519420 0.3110621 0.1312250 0.193675 0.135600 -0.058075 0.01852039 0.01151626    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000114942 E001 0.1187032 1.187577e-02 0.90533693   2 206159585 206159593 9 + 0.077 0.000 -7.596
ENSG00000114942 E002 1.0678172 1.473448e-02 0.07126674 0.27051507 2 206159594 206159606 13 + 0.406 0.117 -2.316
ENSG00000114942 E003 1.5424347 8.133088e-03 0.01193113 0.09017285 2 206159607 206159614 8 + 0.521 0.117 -2.901
ENSG00000114942 E004 2.7841587 7.826030e-02 0.70955226 0.88250603 2 206159615 206159635 21 + 0.591 0.542 -0.223
ENSG00000114942 E005 3.2633768 5.893700e-02 0.61664780 0.83385440 2 206159636 206159637 2 + 0.651 0.579 -0.316
ENSG00000114942 E006 16.2326691 8.900338e-04 0.54537497 0.79134285 2 206159638 206159684 47 + 1.246 1.201 -0.158
ENSG00000114942 E007 9.3818026 9.695456e-03 0.59724177 0.82315337 2 206159685 206159894 210 + 0.986 1.038 0.192
ENSG00000114942 E008 38.0287610 2.366339e-03 0.83918478 0.94234004 2 206159895 206159912 18 + 1.579 1.589 0.037
ENSG00000114942 E009 104.7691666 2.418141e-04 0.93247776 0.98037496 2 206159913 206159926 14 + 2.017 2.014 -0.008
ENSG00000114942 E010 128.1653658 1.432620e-03 0.82073647 0.93501450 2 206159927 206159933 7 + 2.105 2.098 -0.024
ENSG00000114942 E011 160.1753736 1.236275e-04 0.54470947 0.79108202 2 206159934 206159958 25 + 2.204 2.190 -0.049
ENSG00000114942 E012 228.6365285 6.006099e-04 0.26557335 0.55887601 2 206159959 206160018 60 + 2.362 2.338 -0.082
ENSG00000114942 E013 186.9866108 9.888428e-05 0.15394688 0.41900744 2 206160019 206160059 41 + 2.278 2.246 -0.106
ENSG00000114942 E014 0.6069187 2.097748e-01 0.96102205 0.99132444 2 206160440 206160486 47 + 0.198 0.210 0.100
ENSG00000114942 E015 2.2870003 9.583303e-03 0.27595519 0.56934053 2 206160557 206160587 31 + 0.569 0.407 -0.802
ENSG00000114942 E016 500.2804679 8.170369e-04 0.93521209 0.98136377 2 206160588 206160710 123 + 2.691 2.692 0.005
ENSG00000114942 E017 2.0528427 1.706193e-02 0.45241457 0.72564466 2 206160711 206160842 132 + 0.521 0.407 -0.579
ENSG00000114942 E018 2.3226641 1.149424e-02 0.43862649 0.71471777 2 206160843 206160886 44 + 0.467 0.579 0.532
ENSG00000114942 E019 7.0553237 7.309324e-02 0.69388159 0.87489497 2 206160887 206161132 246 + 0.879 0.927 0.182
ENSG00000114942 E020 3.6514017 6.709835e-02 0.60272973 0.82663606 2 206161133 206161190 58 + 0.632 0.702 0.297
ENSG00000114942 E021 2.7733916 1.915664e-01 0.64022455 0.84710933 2 206161321 206161345 25 + 0.612 0.501 -0.509
ENSG00000114942 E022 652.0792497 6.535535e-05 0.66923865 0.86239589 2 206161346 206161472 127 + 2.804 2.809 0.017
ENSG00000114942 E023 530.9959615 2.958321e-04 0.12680729 0.37745634 2 206162038 206162104 67 + 2.708 2.730 0.072
ENSG00000114942 E024 2.5688720 1.010193e-01 0.48396534 0.74831929 2 206162228 206162488 261 + 0.495 0.613 0.546
ENSG00000114942 E025 656.6571564 6.597659e-05 0.65994555 0.85800984 2 206162489 206162614 126 + 2.807 2.812 0.017
ENSG00000114942 E026 278.7318795 7.232878e-05 0.74965059 0.90136559 2 206162729 206162928 200 + 2.440 2.435 -0.018

Help

Please Click HERE to learn more details about the results from DEXseq.