ENSG00000115009

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358813 ENSG00000115009 No_inf pgKDN_inf CCL20 protein_coding protein_coding 204.3879 16.59102 254.7732 0.9769236 2.497101 3.939926 111.736782 8.212595 124.9911798 2.779299 10.5534549 3.9262042 0.52840833 0.503225 0.490975 -0.012250 1.0000000000 0.0001936277    
ENST00000409189 ENSG00000115009 No_inf pgKDN_inf CCL20 protein_coding protein_coding 204.3879 16.59102 254.7732 0.9769236 2.497101 3.939926 75.947659 1.845818 106.6365052 1.114242 7.9493486 5.8446373 0.28955000 0.101025 0.418250 0.317225 0.2030431305 0.0001936277    
ENST00000473642 ENSG00000115009 No_inf pgKDN_inf CCL20 protein_coding protein_coding_CDS_not_defined 204.3879 16.59102 254.7732 0.9769236 2.497101 3.939926 2.106746 2.774578 0.7374365 2.774578 0.7374365 -1.8974359 0.05780833 0.162400 0.002825 -0.159575 0.7569514568 0.0001936277    
ENST00000646475 ENSG00000115009 No_inf pgKDN_inf CCL20 protein_coding protein_coding 204.3879 16.59102 254.7732 0.9769236 2.497101 3.939926 1.206723 1.581707 1.1963906 0.173303 0.3995413 -0.3998779 0.03409167 0.095100 0.004725 -0.090375 0.0001936277 0.0001936277    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115009 E001 0.0000000       2 227805739 227805832 94 +      
ENSG00000115009 E002 0.8420616 0.0940824113 0.068686281 0.26468322 2 227805833 227805890 58 + 0.120 0.460 2.572
ENSG00000115009 E003 2.4953956 0.0068246436 0.575160215 0.80976254 2 227805891 227805969 79 + 0.344 0.460 0.645
ENSG00000115009 E004 1.1962429 0.0105208661 0.144218889 0.40438655 2 227806430 227806433 4 + 0.178 0.460 1.893
ENSG00000115009 E005 2.3988469 0.0085563828 0.042217446 0.20002247 2 227806434 227806569 136 + 0.305 0.679 1.893
ENSG00000115009 E006 0.8355084 0.2000384218 0.389337575 0.67505940 2 227813822 227813841 20 + 0.140 0.289 1.307
ENSG00000115009 E007 0.4726676 0.0550703908 1.000000000   2 227813842 227813842 1 + 0.098 0.001 -7.514
ENSG00000115009 E008 44.8107231 0.0003168362 0.664027629 0.86027482 2 227813843 227813987 145 + 1.373 1.338 -0.123
ENSG00000115009 E009 0.6184028 0.1644278373 0.002364155 0.02891345 2 227815369 227815453 85 + 0.052 0.583 4.478
ENSG00000115009 E010 11.8986652 0.0011577865 0.077834361 0.28544558 2 227815454 227815456 3 + 0.823 1.056 0.877
ENSG00000115009 E011 78.4861485 0.0002201972 0.607570462 0.82915330 2 227815457 227815568 112 + 1.608 1.577 -0.105
ENSG00000115009 E012 0.7086905 0.0140669041 1.000000000 1.00000000 2 227815569 227815984 416 + 0.140 0.000 -8.412
ENSG00000115009 E013 77.8536669 0.0003784821 0.241358444 0.53097676 2 227816307 227816384 78 + 1.607 1.532 -0.258
ENSG00000115009 E014 280.8223204 0.0001861693 0.792479943 0.92081809 2 227817062 227817564 503 + 2.152 2.148 -0.014

Help

Please Click HERE to learn more details about the results from DEXseq.