ENSG00000115073

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000289228 ENSG00000115073 No_inf pgKDN_inf ACTR1B protein_coding protein_coding 48.19785 42.60447 48.65145 0.7870768 0.9853896 0.1914358 20.941137 12.568988 26.587483 1.3710586 1.1869015 1.0802739 0.42825000 0.294625 0.547975 0.253350 0.007358999 0.007358999 FALSE TRUE
MSTRG.16720.2 ENSG00000115073 No_inf pgKDN_inf ACTR1B protein_coding   48.19785 42.60447 48.65145 0.7870768 0.9853896 0.1914358 3.883752 3.851211 2.927494 0.3470593 0.3894901 -0.3944674 0.08070833 0.090200 0.060325 -0.029875 0.762997156 0.007358999 FALSE TRUE
MSTRG.16720.4 ENSG00000115073 No_inf pgKDN_inf ACTR1B protein_coding   48.19785 42.60447 48.65145 0.7870768 0.9853896 0.1914358 4.205269 7.335422 3.038186 1.2646745 1.1563231 -1.2688943 0.09237500 0.172175 0.061925 -0.110250 0.413618445 0.007358999   FALSE
MSTRG.16720.6 ENSG00000115073 No_inf pgKDN_inf ACTR1B protein_coding   48.19785 42.60447 48.65145 0.7870768 0.9853896 0.1914358 11.757346 12.014318 10.321025 0.7322315 0.6362802 -0.2189716 0.24665833 0.283225 0.212300 -0.070925 0.652003224 0.007358999 TRUE TRUE
MSTRG.16720.7 ENSG00000115073 No_inf pgKDN_inf ACTR1B protein_coding   48.19785 42.60447 48.65145 0.7870768 0.9853896 0.1914358 3.869488 3.927828 2.548699 0.6096197 0.1478207 -0.6219895 0.08023333 0.091875 0.052500 -0.039375 0.609955610 0.007358999 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115073 E001 0.0000000       2 97655939 97655954 16 -      
ENSG00000115073 E002 0.0000000       2 97655955 97655962 8 -      
ENSG00000115073 E003 0.9967653 0.4202513384 0.2993955982 0.592309894 2 97655963 97655975 13 - 0.167 0.403 1.707
ENSG00000115073 E004 1.4959309 0.1142193469 0.1063262713 0.341396342 2 97655976 97655977 2 - 0.231 0.518 1.706
ENSG00000115073 E005 190.5890527 0.0037969918 0.9566585464 0.989716280 2 97655978 97656960 983 - 2.281 2.284 0.007
ENSG00000115073 E006 1.7004520 0.0101118841 0.7047908035 0.880048706 2 97656961 97657151 191 - 0.459 0.403 -0.295
ENSG00000115073 E007 20.6892534 0.0041032893 0.1260356318 0.376395980 2 97657152 97657192 41 - 1.385 1.281 -0.360
ENSG00000115073 E008 34.8220499 0.0044394707 0.7508443303 0.901699291 2 97657448 97657509 62 - 1.562 1.546 -0.052
ENSG00000115073 E009 34.1546659 0.0048127616 0.7531205570 0.902820656 2 97657943 97657977 35 - 1.536 1.556 0.068
ENSG00000115073 E010 62.6840483 0.0018921516 0.6622414864 0.859168006 2 97657978 97658117 140 - 1.794 1.813 0.064
ENSG00000115073 E011 4.5596276 0.0074005531 0.1748530890 0.448666754 2 97658118 97658223 106 - 0.655 0.820 0.673
ENSG00000115073 E012 36.2131180 0.0004664581 0.9131403970 0.972460986 2 97658224 97658316 93 - 1.567 1.574 0.022
ENSG00000115073 E013 1.1139203 0.0385996628 0.2771553673 0.570556442 2 97658317 97658368 52 - 0.232 0.403 1.120
ENSG00000115073 E014 59.7989226 0.0002716573 0.8718247864 0.956080560 2 97658427 97658643 217 - 1.786 1.781 -0.016
ENSG00000115073 E015 10.4740116 0.0013448598 0.0467562800 0.212337519 2 97658644 97658737 94 - 0.965 1.139 0.635
ENSG00000115073 E016 8.6274132 0.0017419346 0.0786825637 0.287511205 2 97658738 97658813 76 - 0.893 1.059 0.620
ENSG00000115073 E017 10.2276370 0.0024975076 0.0778469990 0.285463696 2 97658814 97658878 65 - 0.965 1.122 0.576
ENSG00000115073 E018 38.2966353 0.0004012835 0.1783013906 0.453132306 2 97658879 97659003 125 - 1.624 1.562 -0.212
ENSG00000115073 E019 22.8762541 0.0016418939 0.0783518680 0.286574640 2 97659352 97659394 43 - 1.429 1.320 -0.376
ENSG00000115073 E020 28.6091854 0.0005423962 0.0005163285 0.008968651 2 97659395 97659477 83 - 1.556 1.365 -0.656
ENSG00000115073 E021 2.7226578 0.0913571092 0.2045248838 0.487443442 2 97659478 97659891 414 - 0.459 0.660 0.927
ENSG00000115073 E022 29.1376042 0.0009416381 0.2098883003 0.494285023 2 97660571 97660646 76 - 1.511 1.444 -0.232
ENSG00000115073 E023 25.7332265 0.0087761500 0.5258642017 0.778448533 2 97661882 97661946 65 - 1.405 1.448 0.148
ENSG00000115073 E024 9.2534161 0.0015091459 0.0385435443 0.189828100 2 97661947 97662413 467 - 0.905 1.096 0.705
ENSG00000115073 E025 14.4625770 0.0063823143 0.0020811570 0.026342437 2 97662660 97663430 771 - 1.045 1.298 0.903
ENSG00000115073 E026 16.9554587 0.0072961425 0.3795863083 0.666233509 2 97663843 97664044 202 - 1.286 1.219 -0.235

Help

Please Click HERE to learn more details about the results from DEXseq.