ENSG00000115145

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263904 ENSG00000115145 No_inf pgKDN_inf STAM2 protein_coding protein_coding 21.55333 20.43566 15.4597 11.57616 0.7953857 -0.4023494 8.0311065 8.2107205 9.3599636 0.1537386 0.1919713 0.18877859 0.60010000 0.725075 0.608200 -0.116875 0.62210223 0.01999561 FALSE TRUE
ENST00000482997 ENSG00000115145 No_inf pgKDN_inf STAM2 protein_coding retained_intron 21.55333 20.43566 15.4597 11.57616 0.7953857 -0.4023494 2.2135505 0.0000000 4.2366258 0.0000000 1.5530833 8.73017317 0.14468333 0.000000 0.269150 0.269150 0.01999561 0.01999561 FALSE TRUE
ENST00000489389 ENSG00000115145 No_inf pgKDN_inf STAM2 protein_coding retained_intron 21.55333 20.43566 15.4597 11.57616 0.7953857 -0.4023494 0.7976656 0.7919164 0.7418922 0.3281353 0.2782976 -0.09292605 0.05628333 0.050800 0.048825 -0.001975 1.00000000 0.01999561 FALSE TRUE
MSTRG.17108.7 ENSG00000115145 No_inf pgKDN_inf STAM2 protein_coding   21.55333 20.43566 15.4597 11.57616 0.7953857 -0.4023494 9.7200238 11.0711639 0.0000000 11.0711639 0.0000000 -10.11389370 0.14106667 0.200700 0.000000 -0.200700 0.86322628 0.01999561   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115145 E001 145.5114073 0.0002241705 1.153916e-06 5.283134e-05 2 152116801 152120431 3631 - 2.118 2.212 0.313
ENSG00000115145 E002 27.2362906 0.0006287477 8.174919e-01 9.336088e-01 2 152120432 152120802 371 - 1.444 1.457 0.043
ENSG00000115145 E003 21.9502922 0.0009458513 6.915290e-01 8.736091e-01 2 152123766 152123935 170 - 1.372 1.348 -0.085
ENSG00000115145 E004 2.5930757 0.0670337423 2.318357e-01 5.204940e-01 2 152123936 152124686 751 - 0.448 0.649 0.937
ENSG00000115145 E005 0.3533378 0.0157418643 1.386895e-01   2 152126004 152126225 222 - 0.224 0.000 -12.340
ENSG00000115145 E006 15.4372321 0.0009370971 1.966894e-01 4.776102e-01 2 152126226 152126379 154 - 1.169 1.262 0.329
ENSG00000115145 E007 0.2536433 0.0160214177 1.913072e-01   2 152131882 152132113 232 - 0.000 0.185 11.492
ENSG00000115145 E008 8.6696488 0.0223344376 7.825049e-01 9.163544e-01 2 152132114 152132168 55 - 0.970 1.001 0.116
ENSG00000115145 E009 15.3374662 0.0200696460 6.987822e-01 8.772636e-01 2 152133173 152133260 88 - 1.230 1.194 -0.130
ENSG00000115145 E010 15.8904946 0.0008507729 4.703256e-02 2.130031e-01 2 152133402 152133484 83 - 1.290 1.147 -0.506
ENSG00000115145 E011 13.9945016 0.0011928597 2.746982e-01 5.681520e-01 2 152135509 152135603 95 - 1.213 1.130 -0.296
ENSG00000115145 E012 8.7084714 0.0069047582 2.063854e-02 1.294384e-01 2 152143827 152143896 70 - 1.081 0.852 -0.854
ENSG00000115145 E013 8.8917546 0.0028446887 5.628158e-01 8.024870e-01 2 152143897 152143988 92 - 1.020 0.966 -0.201
ENSG00000115145 E014 5.6025477 0.0025585898 7.451071e-01 8.991635e-01 2 152143989 152144013 25 - 0.836 0.800 -0.141
ENSG00000115145 E015 0.0000000       2 152144738 152144836 99 -      
ENSG00000115145 E016 8.1976930 0.0019159545 5.576443e-03 5.363050e-02 2 152144888 152144957 70 - 1.073 0.800 -1.026
ENSG00000115145 E017 11.6989344 0.0012803922 5.702257e-04 9.665164e-03 2 152147162 152147308 147 - 1.219 0.926 -1.064
ENSG00000115145 E018 7.1503582 0.0019557108 1.102458e-01 3.483973e-01 2 152148024 152148122 99 - 0.981 0.818 -0.618
ENSG00000115145 E019 6.2102874 0.0209638447 7.292219e-01 8.920109e-01 2 152148225 152148300 76 - 0.877 0.835 -0.161
ENSG00000115145 E020 0.1265070 0.0122499097 4.566538e-01   2 152148446 152148476 31 - 0.000 0.102 10.537
ENSG00000115145 E021 6.1090573 0.0175676103 7.857820e-01 9.174873e-01 2 152150145 152150229 85 - 0.836 0.868 0.122
ENSG00000115145 E022 6.2783206 0.0022969077 2.661469e-02 1.512281e-01 2 152175603 152175763 161 - 0.960 0.720 -0.933

Help

Please Click HERE to learn more details about the results from DEXseq.