ENSG00000115165

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264192 ENSG00000115165 No_inf pgKDN_inf CYTIP protein_coding protein_coding 55.64495 16.64793 75.27002 1.421222 0.9117432 2.176058 42.75267 9.856187 59.05605 0.3843177 0.6300478 2.581765 0.7250167 0.599150 0.7847 0.185550 0.004296366 0.004296366 FALSE TRUE
MSTRG.17121.1 ENSG00000115165 No_inf pgKDN_inf CYTIP protein_coding   55.64495 16.64793 75.27002 1.421222 0.9117432 2.176058 12.33892 5.381896 16.21397 0.1668498 0.5844733 1.589263 0.2498833 0.328825 0.2153 -0.113525 0.362977110 0.004296366 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115165 E001 110.0590944 1.565288e-04 1.521903e-08 1.045635e-06 2 157412710 157414618 1909 - 1.915 2.090 0.588
ENSG00000115165 E002 257.0510319 8.543682e-05 4.661021e-01 7.349130e-01 2 157414619 157416045 1427 - 2.327 2.313 -0.048
ENSG00000115165 E003 25.5342819 4.800885e-03 1.065723e-01 3.419120e-01 2 157416046 157416070 25 - 1.364 1.235 -0.450
ENSG00000115165 E004 38.7892206 5.047995e-04 4.555685e-02 2.088451e-01 2 157416071 157416143 73 - 1.538 1.415 -0.421
ENSG00000115165 E005 41.5966114 3.432049e-04 1.468801e-01 4.079424e-01 2 157418523 157418589 67 - 1.560 1.476 -0.287
ENSG00000115165 E006 41.4765075 3.554270e-04 6.866731e-01 8.706134e-01 2 157427351 157427420 70 - 1.538 1.560 0.077
ENSG00000115165 E007 44.7616272 3.141191e-04 2.127558e-01 4.979714e-01 2 157430559 157430652 94 - 1.560 1.625 0.222
ENSG00000115165 E008 22.4146956 5.854469e-04 7.573098e-01 9.045634e-01 2 157430860 157430870 11 - 1.281 1.304 0.081
ENSG00000115165 E009 36.4803239 5.190151e-04 3.145923e-01 6.075997e-01 2 157430871 157430912 42 - 1.501 1.439 -0.212
ENSG00000115165 E010 44.2730353 2.464219e-03 4.590540e-01 7.307848e-01 2 157430913 157430962 50 - 1.579 1.536 -0.146
ENSG00000115165 E011 0.4988535 2.363387e-02 1.888729e-02   2 157434161 157434369 209 - 0.050 0.393 3.590
ENSG00000115165 E012 37.7003529 5.979307e-04 6.837508e-01 8.690996e-01 2 157434370 157434415 46 - 1.507 1.483 -0.083
ENSG00000115165 E013 25.2747958 5.322990e-04 8.764820e-01 9.581409e-01 2 157434416 157434424 9 - 1.333 1.344 0.039
ENSG00000115165 E014 0.3712740 1.658996e-02 7.608331e-02   2 157434425 157434697 273 - 0.050 0.297 3.005
ENSG00000115165 E015 23.7202533 5.943457e-04 9.296237e-01 9.793598e-01 2 157434698 157434708 11 - 1.308 1.314 0.023
ENSG00000115165 E016 30.1189791 5.196735e-04 1.784697e-01 4.533622e-01 2 157434709 157434747 39 - 1.426 1.334 -0.317
ENSG00000115165 E017 0.1265070 1.229279e-02 9.992826e-02   2 157438883 157438963 81 - 0.000 0.173 11.524
ENSG00000115165 E018 0.1187032 1.187291e-02 1.000000e+00   2 157439276 157439414 139 - 0.050 0.000 -9.631
ENSG00000115165 E019 51.2853563 3.316833e-04 1.452516e-01 4.055276e-01 2 157443847 157444006 160 - 1.647 1.572 -0.257
ENSG00000115165 E020 12.2776139 1.344597e-03 1.566640e-01 4.230258e-01 2 157444007 157444098 92 - 1.070 0.922 -0.548
ENSG00000115165 E021 0.1170040 1.175606e-02 1.000000e+00   2 157453628 157453852 225 - 0.050 0.000 -9.633
ENSG00000115165 E022 0.0000000       2 157464936 157465027 92 -      
ENSG00000115165 E023 0.0000000       2 157487332 157487434 103 -      
ENSG00000115165 E024 0.0000000       2 157487934 157488035 102 -      
ENSG00000115165 E025 0.0000000       2 157488703 157488919 217 -      
ENSG00000115165 E026 0.0000000       2 157488920 157488961 42 -      

Help

Please Click HERE to learn more details about the results from DEXseq.