ENSG00000115232

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397033 ENSG00000115232 No_inf pgKDN_inf ITGA4 protein_coding protein_coding 64.75457 67.12386 74.85009 1.918471 2.11068 0.1571561 39.824560 32.532804 49.297773 0.7394430 1.080394 0.5994765 0.6232167 0.48670 0.659050 0.172350 0.0073727695 0.0009050333 FALSE TRUE
MSTRG.17297.12 ENSG00000115232 No_inf pgKDN_inf ITGA4 protein_coding   64.75457 67.12386 74.85009 1.918471 2.11068 0.1571561 5.264852 1.412221 8.477082 0.7198058 3.379499 2.5771230 0.0783000 0.02030 0.109675 0.089375 0.5762394223 0.0009050333 FALSE TRUE
MSTRG.17297.9 ENSG00000115232 No_inf pgKDN_inf ITGA4 protein_coding   64.75457 67.12386 74.85009 1.918471 2.11068 0.1571561 13.986541 26.436319 11.817375 1.3674119 1.623305 -1.1609370 0.2099333 0.39345 0.160000 -0.233450 0.0009050333 0.0009050333 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115232 E001 0.1265070 0.0123068138 4.654271e-01   2 181457202 181457206 5 + 0.000 0.101 11.825
ENSG00000115232 E002 1.2059370 0.0099803333 2.956372e-01 5.886983e-01 2 181457207 181457385 179 + 0.415 0.252 -1.020
ENSG00000115232 E003 1.6717432 0.0079540541 1.140069e-02 8.769039e-02 2 181457386 181457403 18 + 0.573 0.183 -2.383
ENSG00000115232 E004 2.7524630 0.0050472920 3.797658e-03 4.096458e-02 2 181457404 181457427 24 + 0.727 0.312 -2.046
ENSG00000115232 E005 30.0431983 0.0004691517 6.277212e-02 2.518262e-01 2 181457428 181457712 285 + 1.538 1.435 -0.354
ENSG00000115232 E006 28.5720566 0.0004912000 4.949618e-02 2.194072e-01 2 181457713 181457851 139 + 1.521 1.410 -0.383
ENSG00000115232 E007 16.0275973 0.0085361352 1.678400e-04 3.631081e-03 2 181458196 181458240 45 + 1.356 1.040 -1.120
ENSG00000115232 E008 21.9771080 0.0007277335 3.787646e-02 1.877773e-01 2 181458241 181458317 77 + 1.420 1.287 -0.463
ENSG00000115232 E009 0.6167962 0.2203362378 5.875599e-01 8.169912e-01 2 181458318 181459391 1074 + 0.163 0.252 0.788
ENSG00000115232 E010 29.2590698 0.0004514932 4.133953e-01 6.941814e-01 2 181474960 181475066 107 + 1.503 1.456 -0.161
ENSG00000115232 E011 0.0000000       2 181475067 181475158 92 +      
ENSG00000115232 E012 35.1824553 0.0020798632 1.434209e-01 4.032989e-01 2 181475159 181475288 130 + 1.595 1.515 -0.271
ENSG00000115232 E013 0.1271363 0.0123470744 4.654622e-01   2 181475289 181475290 2 + 0.000 0.101 11.834
ENSG00000115232 E014 0.4998907 0.0152662843 2.545628e-01 5.462928e-01 2 181475820 181476218 399 + 0.089 0.252 1.787
ENSG00000115232 E015 21.3571556 0.0260547130 6.330224e-02 2.531245e-01 2 181478757 181478824 68 + 1.421 1.257 -0.570
ENSG00000115232 E016 5.9162406 0.0024588081 1.013801e-01 3.324673e-01 2 181478825 181479716 892 + 0.745 0.922 0.687
ENSG00000115232 E017 36.7525771 0.0079900256 8.113100e-01 9.305245e-01 2 181480137 181480266 130 + 1.585 1.568 -0.058
ENSG00000115232 E018 26.9533587 0.0013573574 2.387291e-01 5.277109e-01 2 181481598 181481683 86 + 1.413 1.479 0.228
ENSG00000115232 E019 23.1212703 0.0006535345 5.307456e-01 7.816323e-01 2 181482360 181482422 63 + 1.364 1.401 0.126
ENSG00000115232 E020 45.7917246 0.0003324778 2.756010e-01 5.692285e-01 2 181482514 181482651 138 + 1.647 1.693 0.156
ENSG00000115232 E021 45.6307028 0.0092168959 7.732523e-02 2.844487e-01 2 181485881 181485992 112 + 1.717 1.609 -0.367
ENSG00000115232 E022 5.8825651 0.0052098428 4.419659e-01 7.173015e-01 2 181485993 181486309 317 + 0.796 0.879 0.322
ENSG00000115232 E023 0.5072867 0.0510709282 3.507803e-02 1.792420e-01 2 181493034 181493041 8 + 0.000 0.312 13.833
ENSG00000115232 E024 4.7227636 0.0316016386 1.667815e-02 1.126088e-01 2 181493042 181493324 283 + 0.573 0.894 1.317
ENSG00000115232 E025 41.1968012 0.0013153844 7.653003e-03 6.707135e-02 2 181493325 181493419 95 + 1.683 1.552 -0.447
ENSG00000115232 E026 40.7466553 0.0170574687 1.377683e-01 3.950394e-01 2 181494722 181494812 91 + 1.667 1.565 -0.347
ENSG00000115232 E027 31.1565762 0.0080865813 2.222326e-01 5.095321e-01 2 181495371 181495416 46 + 1.544 1.464 -0.275
ENSG00000115232 E028 64.1145158 0.0035138068 3.759134e-01 6.631292e-01 2 181495783 181495937 155 + 1.833 1.792 -0.139
ENSG00000115232 E029 4.1021869 0.0402350844 2.046833e-02 1.287534e-01 2 181498281 181498571 291 + 0.516 0.847 1.404
ENSG00000115232 E030 1.0151723 0.0115204733 1.120223e-03 1.636461e-02 2 181498572 181498622 51 + 0.000 0.491 14.833
ENSG00000115232 E031 75.9582622 0.0002170376 2.925320e-01 5.860469e-01 2 181498623 181498777 155 + 1.869 1.903 0.114
ENSG00000115232 E032 0.3804973 0.0158896021 7.804903e-02   2 181498871 181498922 52 + 0.000 0.252 13.418
ENSG00000115232 E033 66.8190229 0.0028191308 8.667779e-01 9.541243e-01 2 181509658 181509807 150 + 1.829 1.834 0.017
ENSG00000115232 E034 40.9368082 0.0006587362 1.143633e-02 8.788925e-02 2 181511699 181511775 77 + 1.677 1.555 -0.415
ENSG00000115232 E035 68.2895176 0.0002550541 9.799335e-01 9.977097e-01 2 181522191 181522341 151 + 1.842 1.839 -0.010
ENSG00000115232 E036 0.0000000       2 181523335 181523436 102 +      
ENSG00000115232 E037 57.2146571 0.0002801661 3.736916e-01 6.614353e-01 2 181523437 181523532 96 + 1.782 1.745 -0.125
ENSG00000115232 E038 49.4174402 0.0069815517 7.817114e-01 9.160330e-01 2 181524171 181524250 80 + 1.711 1.693 -0.062
ENSG00000115232 E039 0.0000000       2 181524251 181524365 115 +      
ENSG00000115232 E040 54.4527296 0.0012736502 2.939789e-01 5.873914e-01 2 181525202 181525291 90 + 1.723 1.765 0.144
ENSG00000115232 E041 63.8684094 0.0002349714 9.577520e-01 9.899059e-01 2 181527297 181527387 91 + 1.814 1.810 -0.014
ENSG00000115232 E042 0.0000000       2 181527388 181527450 63 +      
ENSG00000115232 E043 75.8280300 0.0003959088 9.340313e-01 9.810138e-01 2 181529541 181529648 108 + 1.888 1.883 -0.017
ENSG00000115232 E044 72.6602235 0.0002159124 3.003519e-01 5.932152e-01 2 181530524 181530649 126 + 1.850 1.884 0.115
ENSG00000115232 E045 74.9704296 0.0002155461 3.984429e-02 1.935013e-01 2 181531657 181531776 120 + 1.846 1.914 0.230
ENSG00000115232 E046 68.1886507 0.0002663964 1.815154e-01 4.574784e-01 2 181534272 181534370 99 + 1.817 1.863 0.155
ENSG00000115232 E047 51.4913882 0.0002785472 4.497444e-01 7.233211e-01 2 181534816 181534935 120 + 1.705 1.735 0.099
ENSG00000115232 E048 0.3706447 0.2378726900 5.572520e-01   2 181534936 181534984 49 + 0.089 0.183 1.202
ENSG00000115232 E049 72.2499467 0.0009032706 4.411050e-16 8.260609e-14 2 181535432 181538975 3544 + 1.694 1.994 1.013

Help

Please Click HERE to learn more details about the results from DEXseq.