ENSG00000115307

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000377526 ENSG00000115307 No_inf pgKDN_inf AUP1 protein_coding protein_coding 159.6055 108.6936 177.6284 1.229021 2.133244 0.7085439 102.787346 49.525931 125.828252 2.865474 2.373803 1.3450232 0.61826667 0.455500 0.708550 0.253050 2.593842e-08 2.593842e-08 FALSE TRUE
ENST00000425118 ENSG00000115307 No_inf pgKDN_inf AUP1 protein_coding nonsense_mediated_decay 159.6055 108.6936 177.6284 1.229021 2.133244 0.7085439 9.766367 7.775409 12.566407 2.587399 1.627396 0.6918751 0.06325000 0.072275 0.070750 -0.001525 9.486022e-01 2.593842e-08 TRUE TRUE
ENST00000462297 ENSG00000115307 No_inf pgKDN_inf AUP1 protein_coding retained_intron 159.6055 108.6936 177.6284 1.229021 2.133244 0.7085439 8.656274 10.072187 7.865856 1.631194 1.920813 -0.3563000 0.05935833 0.092425 0.043950 -0.048475 3.113303e-01 2.593842e-08   FALSE
ENST00000463900 ENSG00000115307 No_inf pgKDN_inf AUP1 protein_coding retained_intron 159.6055 108.6936 177.6284 1.229021 2.133244 0.7085439 22.905191 26.725637 18.843608 3.597668 1.119235 -0.5039234 0.15742500 0.245900 0.106025 -0.139875 6.592973e-03 2.593842e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115307 E001 2.166190 0.0435856926 1.320386e-01 3.855642e-01 2 74526645 74526651 7 - 0.582 0.341 -1.244
ENSG00000115307 E002 4.107723 0.0275918331 2.217233e-01 5.089775e-01 2 74526652 74526658 7 - 0.766 0.599 -0.700
ENSG00000115307 E003 11.537126 0.0015730547 6.067769e-01 8.288396e-01 2 74526659 74526688 30 - 1.110 1.069 -0.149
ENSG00000115307 E004 38.284107 0.0003859880 6.783478e-01 8.668438e-01 2 74526689 74526745 57 - 1.596 1.579 -0.060
ENSG00000115307 E005 82.405184 0.0001947937 1.101625e-01 3.482969e-01 2 74526746 74526836 91 - 1.936 1.886 -0.170
ENSG00000115307 E006 106.302682 0.0001617486 6.760946e-02 2.623344e-01 2 74526941 74527031 91 - 2.046 1.995 -0.170
ENSG00000115307 E007 80.036864 0.0002128943 4.924936e-02 2.187626e-01 2 74527032 74527059 28 - 1.929 1.865 -0.215
ENSG00000115307 E008 10.838771 0.0045847048 1.617572e-03 2.167506e-02 2 74527060 74527121 62 - 0.927 1.209 1.027
ENSG00000115307 E009 2.604313 0.0086649594 1.807838e-02 1.186243e-01 2 74527122 74527152 31 - 0.382 0.713 1.564
ENSG00000115307 E010 3.097149 0.0100282304 2.165808e-02 1.334370e-01 2 74527153 74527247 95 - 0.449 0.761 1.394
ENSG00000115307 E011 154.828295 0.0001173241 5.480335e-01 7.932972e-01 2 74527248 74527363 116 - 2.192 2.181 -0.038
ENSG00000115307 E012 6.265070 0.0378529570 9.111022e-02 3.134889e-01 2 74527364 74527470 107 - 0.751 0.970 0.847
ENSG00000115307 E013 136.720185 0.0001500684 2.858306e-01 5.793959e-01 2 74527471 74527590 120 - 2.121 2.151 0.100
ENSG00000115307 E014 1.606163 0.1053618452 1.933069e-01 4.731080e-01 2 74527591 74527614 24 - 0.302 0.529 1.242
ENSG00000115307 E015 117.197904 0.0001349724 7.603666e-01 9.062697e-01 2 74527736 74527838 103 - 2.070 2.064 -0.019
ENSG00000115307 E016 9.553692 0.0014863756 2.221419e-06 9.280402e-05 2 74527839 74527939 101 - 0.781 1.217 1.620
ENSG00000115307 E017 81.890475 0.0002893208 7.900736e-01 9.195203e-01 2 74527940 74528006 67 - 1.908 1.920 0.039
ENSG00000115307 E018 17.279984 0.0284518346 3.670504e-04 6.842895e-03 2 74528007 74528247 241 - 1.074 1.425 1.235
ENSG00000115307 E019 92.533752 0.0001810883 3.253897e-01 6.178990e-01 2 74528248 74528321 74 - 1.951 1.985 0.112
ENSG00000115307 E020 89.027080 0.0005085052 7.961758e-01 9.227277e-01 2 74528417 74528489 73 - 1.944 1.956 0.038
ENSG00000115307 E021 75.475070 0.0010589811 8.440286e-01 9.441949e-01 2 74528751 74528821 71 - 1.880 1.876 -0.015
ENSG00000115307 E022 92.721303 0.0001796558 5.432427e-01 7.901845e-01 2 74528822 74528935 114 - 1.973 1.957 -0.054
ENSG00000115307 E023 33.591696 0.0118319900 2.168117e-07 1.167732e-05 2 74528936 74529131 196 - 1.345 1.705 1.234
ENSG00000115307 E024 145.276612 0.0020304668 8.185863e-03 7.020135e-02 2 74529132 74529282 151 - 2.190 2.113 -0.258
ENSG00000115307 E025 4.300131 0.0045568338 1.069933e-01 3.427931e-01 2 74529283 74529361 79 - 0.625 0.823 0.812
ENSG00000115307 E026 82.433693 0.0002862443 2.431374e-02 1.429406e-01 2 74529362 74529499 138 - 1.945 1.872 -0.246
ENSG00000115307 E027 7.815642 0.0037107153 3.148440e-01 6.076723e-01 2 74529580 74529760 181 - 0.895 0.997 0.383

Help

Please Click HERE to learn more details about the results from DEXseq.