ENSG00000115548

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312912 ENSG00000115548 No_inf pgKDN_inf KDM3A protein_coding protein_coding 18.50238 22.65319 15.42611 2.540277 1.361259 -0.5540415 2.078111 2.172833 1.640337 1.2601554 1.6403366 -0.4034414 0.11514167 0.117075 0.084175 -0.032900 0.84309472 0.04575915 FALSE TRUE
ENST00000409064 ENSG00000115548 No_inf pgKDN_inf KDM3A protein_coding protein_coding 18.50238 22.65319 15.42611 2.540277 1.361259 -0.5540415 3.692218 2.095432 5.491275 1.3517091 1.8968561 1.3856494 0.23624167 0.076625 0.390050 0.313425 0.46964779 0.04575915 FALSE TRUE
ENST00000462197 ENSG00000115548 No_inf pgKDN_inf KDM3A protein_coding protein_coding_CDS_not_defined 18.50238 22.65319 15.42611 2.540277 1.361259 -0.5540415 2.733318 3.811616 0.000000 1.4713597 0.0000000 -8.5780391 0.12315833 0.171075 0.000000 -0.171075 0.04575915 0.04575915 FALSE FALSE
ENST00000483866 ENSG00000115548 No_inf pgKDN_inf KDM3A protein_coding retained_intron 18.50238 22.65319 15.42611 2.540277 1.361259 -0.5540415 1.800615 4.189750 1.212096 2.5803053 1.2120957 -1.7809462 0.07429167 0.160675 0.062200 -0.098475 0.82900515 0.04575915 FALSE FALSE
MSTRG.16647.10 ENSG00000115548 No_inf pgKDN_inf KDM3A protein_coding   18.50238 22.65319 15.42611 2.540277 1.361259 -0.5540415 6.201459 6.776572 6.060447 0.8195604 0.5819583 -0.1608801 0.34943333 0.317175 0.401575 0.084400 0.82553984 0.04575915 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115548 E001 0.1271363 0.0122986761 0.555539827   2 86440647 86440800 154 + 0.000 0.094 10.193
ENSG00000115548 E002 0.1271363 0.0122986761 0.555539827   2 86440801 86440962 162 + 0.000 0.094 12.628
ENSG00000115548 E003 0.0000000       2 86441272 86441370 99 +      
ENSG00000115548 E004 0.0000000       2 86441371 86441378 8 +      
ENSG00000115548 E005 0.4989145 0.0282992165 0.337647641   2 86441379 86441444 66 + 0.096 0.237 1.548
ENSG00000115548 E006 0.0000000       2 86441461 86441488 28 +      
ENSG00000115548 E007 0.6350220 0.0142638219 0.022271644 0.13572499 2 86441995 86442017 23 + 0.000 0.344 14.750
ENSG00000115548 E008 4.9291028 0.0031748381 0.399397927 0.68321119 2 86442018 86442233 216 + 0.717 0.817 0.399
ENSG00000115548 E009 0.1268540 0.0122942817 0.555590645   2 86442324 86442594 271 + 0.000 0.094 12.628
ENSG00000115548 E010 0.4918009 0.4458569043 0.982254575   2 86443178 86443534 357 + 0.175 0.171 -0.038
ENSG00000115548 E011 2.4325400 0.0408768260 0.387543935 0.67334549 2 86449807 86449813 7 + 0.599 0.467 -0.622
ENSG00000115548 E012 4.9885490 0.0028717989 0.234891876 0.52406012 2 86449814 86449962 149 + 0.842 0.708 -0.534
ENSG00000115548 E013 5.6062926 0.0025251179 0.323884244 0.61649454 2 86451103 86451213 111 + 0.872 0.766 -0.415
ENSG00000115548 E014 3.8868682 0.0818010847 0.235183118 0.52442908 2 86455085 86455167 83 + 0.775 0.591 -0.775
ENSG00000115548 E015 2.8147779 0.0096019860 0.779513564 0.91500539 2 86455168 86455187 20 + 0.599 0.563 -0.162
ENSG00000115548 E016 0.0000000       2 86456433 86456441 9 +      
ENSG00000115548 E017 5.3804615 0.0069947946 0.694502023 0.87522854 2 86456442 86456566 125 + 0.826 0.784 -0.168
ENSG00000115548 E018 0.0000000       2 86456567 86456655 89 +      
ENSG00000115548 E019 4.4020268 0.0107109453 0.677108611 0.86610234 2 86456805 86456877 73 + 0.757 0.708 -0.197
ENSG00000115548 E020 6.4589599 0.0022833297 0.283708854 0.57740968 2 86456983 86457071 89 + 0.926 0.817 -0.420
ENSG00000115548 E021 0.3711203 0.0164614096 0.603734855   2 86460779 86460831 53 + 0.096 0.171 0.963
ENSG00000115548 E022 9.6093608 0.0034115431 0.231991561 0.52073551 2 86464053 86464216 164 + 0.963 1.075 0.411
ENSG00000115548 E023 13.7555110 0.0049805161 0.577593211 0.81126884 2 86466372 86466631 260 + 1.143 1.190 0.170
ENSG00000115548 E024 9.5138717 0.0099626005 0.330059695 0.62257329 2 86466632 86466777 146 + 1.067 0.976 -0.334
ENSG00000115548 E025 9.4575121 0.0430415345 0.642162127 0.84821676 2 86466778 86466883 106 + 0.986 1.047 0.226
ENSG00000115548 E026 0.0000000       2 86467339 86467368 30 +      
ENSG00000115548 E027 11.7409585 0.0014563778 0.573582602 0.80895081 2 86470204 86470408 205 + 1.127 1.083 -0.157
ENSG00000115548 E028 13.4992192 0.0030479164 0.021065046 0.13115094 2 86474776 86474990 215 + 1.246 1.066 -0.643
ENSG00000115548 E029 8.9345910 0.0182540854 0.005158421 0.05075149 2 86477877 86478029 153 + 1.127 0.832 -1.095
ENSG00000115548 E030 0.0000000       2 86478030 86478169 140 +      
ENSG00000115548 E031 8.9277667 0.0722267241 0.048256374 0.21622159 2 86478170 86478265 96 + 1.126 0.832 -1.094
ENSG00000115548 E032 10.0576922 0.0014234733 0.003678635 0.04008615 2 86478608 86478735 128 + 1.158 0.904 -0.934
ENSG00000115548 E033 4.8359856 0.0104871589 0.054345969 0.23215704 2 86478736 86480166 1431 + 0.626 0.862 0.963
ENSG00000115548 E034 15.4111709 0.0009796008 0.473445701 0.74046396 2 86480167 86480362 196 + 1.240 1.190 -0.174
ENSG00000115548 E035 17.8162752 0.0007926077 0.370222782 0.65849670 2 86481930 86482102 173 + 1.240 1.303 0.223
ENSG00000115548 E036 20.3061578 0.0142265717 0.797375315 0.92348622 2 86482458 86482694 237 + 1.339 1.318 -0.071
ENSG00000115548 E037 2.8580812 0.0051141810 0.070800202 0.26943058 2 86482695 86483986 1292 + 0.437 0.687 1.156
ENSG00000115548 E038 15.6152523 0.0203740908 0.327196030 0.61969276 2 86483987 86484158 172 + 1.264 1.177 -0.307
ENSG00000115548 E039 0.3809703 0.0235131422 0.110472662   2 86484681 86484718 38 + 0.000 0.237 14.067
ENSG00000115548 E040 12.9263488 0.0013606012 0.127356580 0.37846988 2 86484942 86485029 88 + 1.201 1.083 -0.420
ENSG00000115548 E041 20.9455308 0.0006623974 0.893530777 0.96473289 2 86485729 86485859 131 + 1.344 1.338 -0.020
ENSG00000115548 E042 0.8634603 0.5338177574 0.927298371 0.97838159 2 86486928 86487693 766 + 0.242 0.294 0.376
ENSG00000115548 E043 3.2373185 0.0056409115 0.022185391 0.13541726 2 86487694 86489176 1483 + 0.437 0.748 1.404
ENSG00000115548 E044 1.7162096 0.0085502419 0.953518042 0.98854798 2 86489177 86489317 141 + 0.437 0.430 -0.037
ENSG00000115548 E045 17.2995216 0.0008751518 0.687253874 0.87096702 2 86489318 86489437 120 + 1.246 1.276 0.107
ENSG00000115548 E046 0.2457744 0.0162598359 0.980350174   2 86489438 86489519 82 + 0.096 0.094 -0.037
ENSG00000115548 E047 21.6678421 0.0168853065 0.224253706 0.51180177 2 86489520 86489659 140 + 1.298 1.401 0.359
ENSG00000115548 E048 2.9816332 0.0049142101 0.048314090 0.21633642 2 86489660 86490880 1221 + 0.437 0.708 1.243
ENSG00000115548 E049 29.0135681 0.0005637797 0.139345797 0.39690104 2 86490881 86491057 177 + 1.432 1.514 0.282
ENSG00000115548 E050 22.2598143 0.0006455420 0.604347104 0.82743834 2 86491141 86491275 135 + 1.381 1.352 -0.100
ENSG00000115548 E051 0.7258103 0.0142332818 0.392427486 0.67741595 2 86491276 86492038 763 + 0.299 0.171 -1.037
ENSG00000115548 E052 72.5035635 0.0035928297 0.006989168 0.06299878 2 86492039 86492716 678 + 1.806 1.914 0.362

Help

Please Click HERE to learn more details about the results from DEXseq.