ENSG00000115866

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264161 ENSG00000115866 No_inf pgKDN_inf DARS1 protein_coding protein_coding 63.40182 49.3382 78.28282 3.484609 4.045066 0.6658827 5.719455 10.989697 1.449175 1.588938 1.449175 -2.91423874 0.1094667 0.224075 0.019500 -0.204575 0.004057434 0.004057434 FALSE TRUE
ENST00000422708 ENSG00000115866 No_inf pgKDN_inf DARS1 protein_coding protein_coding 63.40182 49.3382 78.28282 3.484609 4.045066 0.6658827 9.877790 9.164068 13.070110 3.540111 2.746977 0.51174117 0.1555500 0.177300 0.166050 -0.011250 0.966577357 0.004057434 FALSE TRUE
ENST00000435076 ENSG00000115866 No_inf pgKDN_inf DARS1 protein_coding retained_intron 63.40182 49.3382 78.28282 3.484609 4.045066 0.6658827 10.491034 1.391353 18.570258 1.391353 1.382185 3.72887831 0.1487167 0.032325 0.237025 0.204700 0.006360664 0.004057434 FALSE TRUE
ENST00000478212 ENSG00000115866 No_inf pgKDN_inf DARS1 protein_coding retained_intron 63.40182 49.3382 78.28282 3.484609 4.045066 0.6658827 14.962401 15.313465 15.854629 2.246340 2.882019 0.05007124 0.2412583 0.308375 0.199300 -0.109075 0.434713280 0.004057434   FALSE
MSTRG.17034.2 ENSG00000115866 No_inf pgKDN_inf DARS1 protein_coding   63.40182 49.3382 78.28282 3.484609 4.045066 0.6658827 20.896614 9.544085 29.159591 1.763009 2.946783 1.61027550 0.3188250 0.200400 0.376050 0.175650 0.198736870 0.004057434 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115866 E001 0.3713386 0.1524757975 0.472351192   2 135905881 135906068 188 - 0.084 0.193 1.392
ENSG00000115866 E002 20.3457128 0.0166810572 0.831967086 0.93927831 2 135906069 135906823 755 - 1.319 1.337 0.063
ENSG00000115866 E003 109.3839782 0.0002658431 0.727537725 0.89128456 2 135906824 135907243 420 - 2.035 2.048 0.046
ENSG00000115866 E004 14.1346838 0.0009334330 0.933001685 0.98062118 2 135907244 135907259 16 - 1.179 1.177 -0.009
ENSG00000115866 E005 52.2309871 0.0002727849 0.434016213 0.71126951 2 135907260 135907407 148 - 1.708 1.743 0.121
ENSG00000115866 E006 0.3614886 0.0165823796 0.757847052   2 135910848 135911138 291 - 0.155 0.107 -0.608
ENSG00000115866 E007 37.5104863 0.0109451168 0.039712166 0.19313219 2 135911139 135911210 72 - 1.519 1.651 0.448
ENSG00000115866 E008 52.8361126 0.0109055715 0.170306721 0.44251513 2 135911382 135911493 112 - 1.691 1.771 0.271
ENSG00000115866 E009 0.0000000       2 135911494 135911617 124 -      
ENSG00000115866 E010 44.5239735 0.0003027606 0.322503595 0.61549571 2 135912486 135912566 81 - 1.674 1.634 -0.134
ENSG00000115866 E011 31.1100604 0.0005015404 0.002296247 0.02830418 2 135914469 135914511 43 - 1.570 1.409 -0.550
ENSG00000115866 E012 1.1171938 0.0429515372 0.182438619 0.45884645 2 135914512 135914866 355 - 0.215 0.429 1.392
ENSG00000115866 E013 58.3119953 0.0003907248 0.487494942 0.75091417 2 135916226 135916372 147 - 1.781 1.759 -0.076
ENSG00000115866 E014 48.5616253 0.0024771389 0.645169987 0.84979603 2 135920453 135920600 148 - 1.681 1.707 0.086
ENSG00000115866 E015 41.1186969 0.0005340785 0.705078050 0.88015663 2 135922784 135922918 135 - 1.612 1.634 0.074
ENSG00000115866 E016 17.5420532 0.0007820962 0.915417296 0.97352098 2 135924387 135924417 31 - 1.268 1.264 -0.012
ENSG00000115866 E017 16.4218248 0.0040550874 0.658566645 0.85732179 2 135924418 135924436 19 - 1.252 1.223 -0.105
ENSG00000115866 E018 26.6071699 0.0011868714 0.211723278 0.49676266 2 135924437 135924498 62 - 1.469 1.400 -0.237
ENSG00000115866 E019 24.6214688 0.0006498012 0.983545895 0.99869026 2 135932783 135932842 60 - 1.404 1.409 0.018
ENSG00000115866 E020 0.0000000       2 135933909 135933909 1 -      
ENSG00000115866 E021 23.2507605 0.0006090293 0.129787664 0.38211517 2 135933910 135933990 81 - 1.337 1.433 0.331
ENSG00000115866 E022 0.0000000       2 135943179 135943377 199 -      
ENSG00000115866 E023 11.3882011 0.0015573838 0.251479750 0.54260230 2 135943378 135943385 8 - 1.043 1.143 0.361
ENSG00000115866 E024 30.4840205 0.0004347353 0.870570091 0.95541090 2 135943386 135943480 95 - 1.490 1.503 0.044
ENSG00000115866 E025 32.8532537 0.0004417197 0.013221993 0.09636209 2 135961396 135961498 103 - 1.579 1.454 -0.428
ENSG00000115866 E026 0.2537694 0.0160203483 0.165212616   2 135978987 135979273 287 - 0.000 0.193 11.172
ENSG00000115866 E027 24.0191802 0.0011824731 0.082989976 0.29689449 2 135979274 135979366 93 - 1.439 1.337 -0.353
ENSG00000115866 E028 0.0000000       2 135980431 135980551 121 -      
ENSG00000115866 E029 7.5679611 0.0033344657 0.797740871 0.92380567 2 135983397 135983454 58 - 0.917 0.947 0.112
ENSG00000115866 E030 0.3533378 0.0157208011 0.164154956   2 135985403 135985626 224 - 0.215 0.000 -11.670
ENSG00000115866 E031 0.2452102 0.0162670326 0.838470424   2 135985794 135985812 19 - 0.084 0.107 0.392
ENSG00000115866 E032 0.2452102 0.0162670326 0.838470424   2 135985813 135985897 85 - 0.084 0.107 0.392
ENSG00000115866 E033 0.0000000       2 135985930 135986100 171 -      

Help

Please Click HERE to learn more details about the results from DEXseq.