ENSG00000115875

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313117 ENSG00000115875 No_inf pgKDN_inf SRSF7 protein_coding protein_coding 114.3436 92.70666 124.6118 2.306976 3.945903 0.4266564 12.03518 11.68582 12.36625 1.327491 1.0922493 0.08158174 0.1076917 0.127100 0.099475 -0.027625 8.229988e-01 2.098802e-05 FALSE TRUE
ENST00000409276 ENSG00000115875 No_inf pgKDN_inf SRSF7 protein_coding protein_coding 114.3436 92.70666 124.6118 2.306976 3.945903 0.4266564 51.31585 29.03171 64.71998 2.048703 2.1043638 1.15630781 0.4372167 0.312200 0.519700 0.207500 3.270222e-05 2.098802e-05 FALSE TRUE
ENST00000443213 ENSG00000115875 No_inf pgKDN_inf SRSF7 protein_coding nonsense_mediated_decay 114.3436 92.70666 124.6118 2.306976 3.945903 0.4266564 22.32208 28.86097 17.59149 0.584314 0.6509941 -0.71392173 0.2054917 0.311975 0.141250 -0.170725 2.098802e-05 2.098802e-05 TRUE TRUE
ENST00000452806 ENSG00000115875 No_inf pgKDN_inf SRSF7 protein_coding protein_coding 114.3436 92.70666 124.6118 2.306976 3.945903 0.4266564 20.05469 12.60422 22.36560 1.399645 1.9659877 0.82687613 0.1712000 0.135300 0.178900 0.043600 6.425996e-01 2.098802e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115875 E001 0.126854 0.0123179582 5.214360e-01   2 38743599 38743600 2 - 0.000 0.097 9.658
ENSG00000115875 E002 59.570526 0.0032859199 3.313718e-03 3.725705e-02 2 38743601 38744452 852 - 1.710 1.842 0.448
ENSG00000115875 E003 20.708805 0.0090249011 3.084282e-02 1.652898e-01 2 38744453 38744716 264 - 1.245 1.409 0.573
ENSG00000115875 E004 13.217266 0.0032888387 9.828823e-01 9.986903e-01 2 38744717 38744892 176 - 1.153 1.153 -0.001
ENSG00000115875 E005 4.125853 0.0034222287 2.047660e-01 4.878672e-01 2 38744893 38744894 2 - 0.782 0.627 -0.639
ENSG00000115875 E006 7.835875 0.0017561447 8.980315e-01 9.663490e-01 2 38744895 38744917 23 - 0.939 0.953 0.052
ENSG00000115875 E007 64.870378 0.0018876907 4.197324e-01 6.991738e-01 2 38744918 38745052 135 - 1.834 1.803 -0.105
ENSG00000115875 E008 116.514039 0.0001314787 6.629362e-02 2.592809e-01 2 38745053 38745187 135 - 2.094 2.046 -0.160
ENSG00000115875 E009 74.781288 0.0002324718 2.836151e-01 5.773580e-01 2 38746144 38746179 36 - 1.897 1.862 -0.117
ENSG00000115875 E010 87.826669 0.0001885818 1.402134e-02 1.001758e-01 2 38746694 38746747 54 - 1.985 1.910 -0.253
ENSG00000115875 E011 7.033561 0.0020762130 6.718603e-02 2.614249e-01 2 38746748 38747044 297 - 0.798 0.988 0.722
ENSG00000115875 E012 2.818778 0.0051050998 7.774659e-01 9.145948e-01 2 38747062 38747130 69 - 0.562 0.601 0.178
ENSG00000115875 E013 43.901622 0.0003237431 5.485620e-02 2.332874e-01 2 38748047 38748055 9 - 1.693 1.609 -0.286
ENSG00000115875 E014 51.533848 0.0002778742 1.817620e-01 4.577682e-01 2 38748056 38748079 24 - 1.747 1.693 -0.181
ENSG00000115875 E015 83.268901 0.0002156086 4.814082e-01 7.464458e-01 2 38748080 38748157 78 - 1.936 1.915 -0.071
ENSG00000115875 E016 96.199523 0.0002367476 2.697208e-01 5.633438e-01 2 38748579 38748653 75 - 2.003 1.972 -0.105
ENSG00000115875 E017 36.234520 0.0003993481 5.478442e-11 5.737365e-09 2 38748654 38748897 244 - 1.368 1.704 1.150
ENSG00000115875 E018 38.579827 0.0004327819 6.503973e-11 6.694376e-09 2 38748898 38749173 276 - 1.403 1.727 1.108
ENSG00000115875 E019 33.167812 0.0004337492 4.402181e-18 1.014646e-15 2 38749174 38749346 173 - 1.227 1.706 1.652
ENSG00000115875 E020 29.384940 0.0031795037 2.777704e-04 5.455670e-03 2 38749347 38749528 182 - 1.359 1.576 0.744
ENSG00000115875 E021 162.014376 0.0001162758 7.802687e-02 2.857650e-01 2 38749529 38749705 177 - 2.231 2.193 -0.126
ENSG00000115875 E022 101.110776 0.0011545881 1.872785e-05 5.828437e-04 2 38750014 38750194 181 - 2.072 1.938 -0.449
ENSG00000115875 E023 0.126854 0.0123179582 5.214360e-01   2 38750824 38751228 405 - 0.000 0.097 9.661
ENSG00000115875 E024 44.343000 0.0006238079 1.367517e-04 3.069315e-03 2 38751229 38751494 266 - 1.735 1.564 -0.582

Help

Please Click HERE to learn more details about the results from DEXseq.