ENSG00000115935

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000392547 ENSG00000115935 No_inf pgKDN_inf WIPF1 protein_coding protein_coding 37.36269 35.55804 42.76071 0.5317369 1.083945 0.2660419 13.497620 18.239274 9.780879 3.5080830 2.7320610 -0.89832884 0.37098333 0.515325 0.225125 -0.29020 0.233948470 0.004512072 FALSE TRUE
ENST00000409415 ENSG00000115935 No_inf pgKDN_inf WIPF1 protein_coding protein_coding 37.36269 35.55804 42.76071 0.5317369 1.083945 0.2660419 2.204966 2.031411 2.132068 0.2086359 0.1577869 0.06943757 0.05940833 0.057000 0.050200 -0.00680 0.957639930 0.004512072 FALSE TRUE
ENST00000679041 ENSG00000115935 No_inf pgKDN_inf WIPF1 protein_coding protein_coding 37.36269 35.55804 42.76071 0.5317369 1.083945 0.2660419 10.843861 2.031578 17.643779 2.0315776 1.9288065 3.11222067 0.28360833 0.056075 0.415925 0.35985 0.004512072 0.004512072 FALSE TRUE
ENST00000698666 ENSG00000115935 No_inf pgKDN_inf WIPF1 protein_coding retained_intron 37.36269 35.55804 42.76071 0.5317369 1.083945 0.2660419 3.007136 2.637345 5.721853 2.6373449 3.3444702 1.11445536 0.07605833 0.072775 0.134875 0.06210 0.845658716 0.004512072 FALSE TRUE
MSTRG.17265.1 ENSG00000115935 No_inf pgKDN_inf WIPF1 protein_coding   37.36269 35.55804 42.76071 0.5317369 1.083945 0.2660419 2.833253 3.309722 4.140499 1.3089073 0.5654617 0.32222251 0.07422500 0.093575 0.096725 0.00315 0.913272524 0.004512072 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115935 E001 0.6340457 1.777323e-01 2.381418e-02 0.141216657 2 174559430 174559571 142 - 0.000 0.371 12.592
ENSG00000115935 E002 0.0000000       2 174559572 174559573 2 -      
ENSG00000115935 E003 1.1251600 5.456119e-02 5.945998e-02 0.244634555 2 174559574 174559581 8 - 0.160 0.460 2.086
ENSG00000115935 E004 1.6240131 7.585928e-02 3.784650e-02 0.187715029 2 174559582 174559583 2 - 0.222 0.568 2.015
ENSG00000115935 E005 10.4236643 1.637165e-03 2.391656e-01 0.528122614 2 174559584 174559678 95 - 1.005 1.109 0.381
ENSG00000115935 E006 211.9975577 1.524644e-04 1.872907e-01 0.465347220 2 174559679 174560769 1091 - 2.315 2.342 0.091
ENSG00000115935 E007 280.7886801 7.595822e-05 1.380834e-01 0.395422510 2 174560770 174562125 1356 - 2.458 2.438 -0.067
ENSG00000115935 E008 25.5096553 5.323856e-04 9.704278e-01 0.994112865 2 174562126 174562203 78 - 1.420 1.425 0.016
ENSG00000115935 E009 13.7977502 2.789277e-03 7.422193e-01 0.898015949 2 174562204 174562210 7 - 1.156 1.184 0.100
ENSG00000115935 E010 55.0190054 3.896330e-04 9.673654e-01 0.993412053 2 174562211 174562550 340 - 1.747 1.748 0.003
ENSG00000115935 E011 19.0953370 9.007971e-04 2.514178e-01 0.542578075 2 174562551 174562602 52 - 1.336 1.261 -0.260
ENSG00000115935 E012 2.1229907 6.859167e-03 9.765404e-03 0.079097424 2 174566161 174567069 909 - 0.276 0.654 1.980
ENSG00000115935 E013 13.0022411 1.126780e-03 2.868982e-01 0.580259002 2 174567070 174567076 7 - 1.182 1.100 -0.294
ENSG00000115935 E014 29.6229473 4.733796e-04 6.842730e-01 0.869327950 2 174567077 174567183 107 - 1.494 1.475 -0.067
ENSG00000115935 E015 42.9727956 6.348933e-03 8.979972e-01 0.966348967 2 174567861 174568073 213 - 1.638 1.648 0.033
ENSG00000115935 E016 1.9478881 7.380656e-03 9.009021e-01 0.967971231 2 174568607 174568823 217 - 0.477 0.461 -0.083
ENSG00000115935 E017 2.1118468 6.663735e-03 3.764635e-02 0.187135319 2 174570439 174570646 208 - 0.324 0.627 1.542
ENSG00000115935 E018 10.0692195 1.326947e-03 1.338177e-01 0.388759566 2 174571169 174571675 507 - 0.975 1.109 0.491
ENSG00000115935 E019 95.4893853 3.192012e-03 1.387135e-01 0.396065824 2 174571676 174572323 648 - 2.007 1.955 -0.174
ENSG00000115935 E020 19.6558604 7.114266e-04 3.318657e-02 0.173143286 2 174572324 174572446 123 - 1.374 1.235 -0.486
ENSG00000115935 E021 0.3804973 1.581391e-02 7.179609e-02   2 174574730 174574941 212 - 0.000 0.257 13.938
ENSG00000115935 E022 3.4681823 4.477648e-02 1.661079e-02 0.112308694 2 174575204 174575371 168 - 0.786 0.418 -1.659
ENSG00000115935 E023 0.0000000       2 174575372 174575380 9 -      
ENSG00000115935 E024 0.5085150 1.591533e-02 2.865417e-02 0.158506074 2 174575381 174575566 186 - 0.000 0.318 14.327
ENSG00000115935 E025 0.2543986 1.600422e-02 1.846976e-01   2 174581140 174581309 170 - 0.000 0.187 13.381
ENSG00000115935 E026 9.2111838 4.705128e-03 9.530994e-02 0.321398421 2 174581310 174581439 130 - 1.075 0.918 -0.581
ENSG00000115935 E027 13.3279243 1.712045e-03 2.372059e-02 0.140912679 2 174585523 174585611 89 - 1.230 1.051 -0.643
ENSG00000115935 E028 12.6782258 4.091902e-03 2.800756e-03 0.032767020 2 174597601 174597858 258 - 1.236 0.984 -0.911
ENSG00000115935 E029 0.0000000       2 174598171 174598175 5 -      
ENSG00000115935 E030 0.0000000       2 174598176 174598217 42 -      
ENSG00000115935 E031 1.5845106 4.625089e-02 9.525863e-01 0.988251789 2 174615112 174615570 459 - 0.407 0.418 0.057
ENSG00000115935 E032 5.4668340 2.590776e-03 8.632342e-04 0.013382487 2 174615571 174616530 960 - 0.590 0.971 1.533
ENSG00000115935 E033 2.5005335 3.868074e-02 3.558433e-03 0.039189826 2 174621107 174623398 2292 - 0.276 0.725 2.279
ENSG00000115935 E034 1.5963160 1.275497e-01 6.599777e-01 0.858026645 2 174623399 174623480 82 - 0.368 0.460 0.501
ENSG00000115935 E035 1.3692331 1.759926e-01 1.515360e-01 0.414923214 2 174623481 174623508 28 - 0.222 0.499 1.693
ENSG00000115935 E036 1.4978149 1.866321e-02 4.172268e-02 0.198681902 2 174625624 174625820 197 - 0.222 0.535 1.864
ENSG00000115935 E037 1.3713730 5.912666e-02 8.785585e-02 0.307409763 2 174625821 174625856 36 - 0.222 0.499 1.694
ENSG00000115935 E038 1.7399097 7.917051e-03 5.093825e-02 0.223325459 2 174625857 174625960 104 - 0.276 0.568 1.601
ENSG00000115935 E039 2.8192507 4.644037e-02 5.767148e-01 0.810604955 2 174629666 174629868 203 - 0.537 0.627 0.405
ENSG00000115935 E040 1.1250664 1.290730e-02 4.957743e-02 0.219632591 2 174630382 174630560 179 - 0.160 0.461 2.087
ENSG00000115935 E041 0.1272623 1.234375e-02 4.455177e-01   2 174630561 174630625 65 - 0.000 0.104 12.437
ENSG00000115935 E042 0.2536433 1.596695e-02 1.847492e-01   2 174630626 174630696 71 - 0.000 0.187 13.381
ENSG00000115935 E043 0.7451009 1.323494e-02 2.971933e-01 0.590358438 2 174631093 174631225 133 - 0.160 0.318 1.279
ENSG00000115935 E044 3.6711554 3.885562e-03 6.116971e-01 0.831065492 2 174634518 174634605 88 - 0.637 0.703 0.279
ENSG00000115935 E045 0.3709916 1.639562e-02 4.739197e-01   2 174673267 174673816 550 - 0.087 0.187 1.279
ENSG00000115935 E046 4.4990902 3.746141e-03 8.670219e-05 0.002113057 2 174674647 174676312 1666 - 0.444 0.932 2.087
ENSG00000115935 E047 1.0076205 9.872358e-02 2.300622e-02 0.138391433 2 174676313 174676666 354 - 0.087 0.461 3.086
ENSG00000115935 E048 0.0000000       2 174677028 174677044 17 -      
ENSG00000115935 E049 0.3808443 2.886810e-02 7.338184e-02   2 174677045 174677124 80 - 0.000 0.257 13.866
ENSG00000115935 E050 0.2533610 1.597937e-02 1.846738e-01   2 174677125 174677739 615 - 0.000 0.187 13.381
ENSG00000115935 E051 0.8705042 2.787356e-02 1.720373e-01 0.444742355 2 174682774 174682916 143 - 0.160 0.371 1.601

Help

Please Click HERE to learn more details about the results from DEXseq.