ENSG00000115956

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000234313 ENSG00000115956 No_inf pgKDN_inf PLEK protein_coding protein_coding 143.6932 137.9489 150.8263 1.056483 0.6836243 0.128745 138.22769 128.352802 147.960744 1.689916 0.9988034 0.2050848 0.96124167 0.930375 0.98105 0.050675 0.0004339591 0.0004339591 FALSE  
ENST00000474788 ENSG00000115956 No_inf pgKDN_inf PLEK protein_coding retained_intron 143.6932 137.9489 150.8263 1.056483 0.6836243 0.128745 5.46553 9.596124 2.865573 1.104574 0.9733255 -1.7401049 0.03875833 0.069625 0.01895 -0.050675 0.0502568237 0.0004339591 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000115956 E001 36.722652 8.732914e-04 5.376694e-01 7.866923e-01 2 68365282 68365393 112 + 1.591 1.561 -0.103
ENSG00000115956 E002 85.633390 5.988633e-04 2.807112e-02 1.565816e-01 2 68380328 68380483 156 + 1.974 1.901 -0.245
ENSG00000115956 E003 143.776028 1.161220e-04 7.290904e-03 6.487834e-02 2 68380723 68380904 182 + 2.193 2.128 -0.220
ENSG00000115956 E004 96.913490 8.292610e-04 5.847836e-03 5.540087e-02 2 68382542 68382633 92 + 2.034 1.946 -0.296
ENSG00000115956 E005 125.838832 1.319148e-04 4.041637e-05 1.110469e-03 2 68386502 68386686 185 + 2.156 2.048 -0.363
ENSG00000115956 E006 6.706573 2.549215e-03 3.452666e-03 3.834641e-02 2 68387942 68388386 445 + 0.695 1.009 1.222
ENSG00000115956 E007 93.340245 1.724743e-04 3.012363e-01 5.942530e-01 2 68388387 68388491 105 + 1.990 1.959 -0.106
ENSG00000115956 E008 87.458371 4.175420e-03 4.099034e-01 6.920127e-01 2 68393162 68393245 84 + 1.963 1.930 -0.111
ENSG00000115956 E009 104.555059 1.757029e-04 6.230102e-01 8.376975e-01 2 68394107 68394176 70 + 2.030 2.016 -0.046
ENSG00000115956 E010 1454.229168 5.527174e-05 1.901769e-10 1.848108e-08 2 68395680 68397453 1774 + 3.146 3.177 0.105

Help

Please Click HERE to learn more details about the results from DEXseq.