ENSG00000116030

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000392244 ENSG00000116030 No_inf pgKDN_inf SUMO1 protein_coding protein_coding 103.9322 98.95228 117.662 3.438176 2.583129 0.2498204 26.736217 23.90737 28.83872 2.729209 3.509753 0.27044849 0.2587167 0.24075 0.243575 0.002825 1.000000e+00 1.159011e-13   FALSE
ENST00000392246 ENSG00000116030 No_inf pgKDN_inf SUMO1 protein_coding protein_coding 103.9322 98.95228 117.662 3.438176 2.583129 0.2498204 61.570534 68.28971 65.51270 1.256906 2.039245 -0.05988463 0.5954167 0.69170 0.558375 -0.133325 5.404564e-02 1.159011e-13 FALSE FALSE
ENST00000409181 ENSG00000116030 No_inf pgKDN_inf SUMO1 protein_coding protein_coding 103.9322 98.95228 117.662 3.438176 2.583129 0.2498204 9.682278 0.00000 14.35904 0.000000 2.849690 10.48874800 0.0903000 0.00000 0.121200 0.121200 1.159011e-13 1.159011e-13   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116030 E001 0.1272623 0.0123549769 5.686018e-01   2 202206182 202206186 5 - 0.000 0.093 11.073
ENSG00000116030 E002 16.0276052 0.0008892378 7.426105e-02 0.277795886 2 202206187 202206649 463 - 1.157 1.286 0.457
ENSG00000116030 E003 72.5433200 0.0002176200 1.178105e-03 0.016962068 2 202206650 202206767 118 - 1.802 1.915 0.378
ENSG00000116030 E004 68.8227555 0.0003316296 6.480952e-05 0.001645686 2 202206768 202206803 36 - 1.761 1.904 0.484
ENSG00000116030 E005 74.8811498 0.0002121216 3.823276e-01 0.668561890 2 202206804 202206850 47 - 1.863 1.893 0.098
ENSG00000116030 E006 55.3065233 0.0002621924 8.319600e-01 0.939278313 2 202206851 202206869 19 - 1.745 1.753 0.027
ENSG00000116030 E007 129.0363838 0.0019291947 9.972573e-01 1.000000000 2 202206870 202207007 138 - 2.114 2.113 -0.002
ENSG00000116030 E008 44.8214941 0.0040112730 8.499485e-01 0.946799781 2 202207008 202207030 23 - 1.666 1.656 -0.034
ENSG00000116030 E009 95.3174442 0.0027466843 4.617923e-01 0.732344502 2 202207031 202207141 111 - 1.969 1.995 0.086
ENSG00000116030 E010 99.7407619 0.0001716142 1.927883e-01 0.472597402 2 202207142 202207245 104 - 2.022 1.984 -0.128
ENSG00000116030 E011 44.1646343 0.0003345096 1.066461e-02 0.083778571 2 202207246 202207252 7 - 1.711 1.597 -0.386
ENSG00000116030 E012 69.7310945 0.0002784391 7.212827e-03 0.064353453 2 202207253 202207321 69 - 1.897 1.802 -0.320
ENSG00000116030 E013 0.4990093 0.0311592457 3.510033e-01   2 202207868 202208002 135 - 0.098 0.234 1.503
ENSG00000116030 E014 47.8431825 0.0072550420 3.498356e-01 0.640072274 2 202210735 202210783 49 - 1.715 1.662 -0.178
ENSG00000116030 E015 44.3961288 0.0061354941 9.976910e-01 1.000000000 2 202210784 202210806 23 - 1.656 1.656 -0.002
ENSG00000116030 E016 35.3011010 0.0038320202 7.523838e-01 0.902459274 2 202214357 202214429 73 - 1.568 1.550 -0.062
ENSG00000116030 E017 0.3543453 0.0157453794 9.273067e-02   2 202214430 202214434 5 - 0.244 0.000 -12.929
ENSG00000116030 E018 15.1403394 0.0012754263 1.695926e-01 0.441597470 2 202220032 202220106 75 - 1.258 1.156 -0.362
ENSG00000116030 E019 0.0000000       2 202221797 202222006 210 -      
ENSG00000116030 E020 0.2533610 0.0159861125 2.620861e-01   2 202231543 202231732 190 - 0.000 0.169 12.075
ENSG00000116030 E021 0.1186381 0.0118415548 5.091685e-01   2 202233578 202233670 93 - 0.098 0.000 -11.344
ENSG00000116030 E022 44.4337596 0.0003399584 2.566602e-02 0.147955453 2 202238440 202238599 160 - 1.706 1.607 -0.336

Help

Please Click HERE to learn more details about the results from DEXseq.