ENSG00000116337

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000342115 ENSG00000116337 No_inf pgKDN_inf AMPD2 protein_coding protein_coding 36.92839 19.87501 40.00434 1.199637 1.908863 1.008836 8.3132494 2.735452 14.3148768 2.735452 2.5180206 2.3834071 0.22523333 0.158225 0.358875 0.200650 0.06456740 0.03198792 FALSE TRUE
ENST00000474459 ENSG00000116337 No_inf pgKDN_inf AMPD2 protein_coding retained_intron 36.92839 19.87501 40.00434 1.199637 1.908863 1.008836 3.3285998 3.115147 2.5785218 1.385779 0.5077310 -0.2717957 0.10405000 0.156750 0.064600 -0.092150 0.83691150 0.03198792 FALSE TRUE
ENST00000476688 ENSG00000116337 No_inf pgKDN_inf AMPD2 protein_coding protein_coding 36.92839 19.87501 40.00434 1.199637 1.908863 1.008836 8.1810445 1.779137 14.3918225 1.779137 2.6441338 3.0089158 0.20483333 0.083325 0.364050 0.280725 0.03198792 0.03198792 FALSE TRUE
ENST00000479919 ENSG00000116337 No_inf pgKDN_inf AMPD2 protein_coding retained_intron 36.92839 19.87501 40.00434 1.199637 1.908863 1.008836 1.3492249 2.732967 0.6699535 1.584278 0.6699535 -2.0122293 0.05170000 0.125175 0.014750 -0.110425 0.67313018 0.03198792 TRUE TRUE
ENST00000652975 ENSG00000116337 No_inf pgKDN_inf AMPD2 protein_coding nonsense_mediated_decay 36.92839 19.87501 40.00434 1.199637 1.908863 1.008836 0.3356516 1.006955 0.0000000 1.006955 0.0000000 -6.6681116 0.01818333 0.054550 0.000000 -0.054550 0.81598880 0.03198792 TRUE TRUE
ENST00000680192 ENSG00000116337 No_inf pgKDN_inf AMPD2 protein_coding retained_intron 36.92839 19.87501 40.00434 1.199637 1.908863 1.008836 1.8977055 1.182011 0.9901355 0.623946 0.6144194 -0.2532025 0.05029167 0.055875 0.026450 -0.029425 0.81812759 0.03198792 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116337 E001 0.9860590 0.1971873527 2.234953e-01 0.511109017 1 109616104 109616235 132 + 0.192 0.418 1.542
ENSG00000116337 E002 8.4733032 0.0137003046 5.599107e-01 0.800652813 1 109616236 109618324 2089 + 0.987 0.926 -0.226
ENSG00000116337 E003 0.0000000       1 109619504 109619656 153 +      
ENSG00000116337 E004 0.0000000       1 109619831 109619836 6 +      
ENSG00000116337 E005 0.0000000       1 109619837 109619844 8 +      
ENSG00000116337 E006 0.0000000       1 109619845 109619845 1 +      
ENSG00000116337 E007 13.1867483 0.0098107817 4.759063e-01 0.742544337 1 109619846 109620139 294 + 1.162 1.102 -0.215
ENSG00000116337 E008 12.6430704 0.0096224860 4.613485e-01 0.732114317 1 109620140 109620278 139 + 1.096 1.164 0.243
ENSG00000116337 E009 0.2362687 0.0157176497 4.976719e-01   1 109620608 109620651 44 + 0.137 0.000 -13.179
ENSG00000116337 E010 0.9721490 0.0119016452 9.570939e-01 0.989759257 1 109620654 109620913 260 + 0.285 0.295 0.068
ENSG00000116337 E011 0.3703650 0.0166613218 2.990019e-01   1 109620914 109620917 4 + 0.074 0.217 1.805
ENSG00000116337 E012 0.3703650 0.0166613218 2.990019e-01   1 109620918 109620927 10 + 0.074 0.217 1.805
ENSG00000116337 E013 0.3714026 0.0166375212 2.990879e-01   1 109620928 109620950 23 + 0.074 0.217 1.805
ENSG00000116337 E014 0.5080420 0.0160442319 1.089270e-02 0.085056769 1 109620951 109620957 7 + 0.000 0.361 14.450
ENSG00000116337 E015 0.5080420 0.0160442319 1.089270e-02 0.085056769 1 109620958 109620967 10 + 0.000 0.361 14.450
ENSG00000116337 E016 1.0071774 0.0119330155 3.095414e-03 0.035303033 1 109620968 109621031 64 + 0.074 0.514 3.612
ENSG00000116337 E017 0.6178386 0.0143877424 2.921984e-01 0.585663058 1 109621032 109621073 42 + 0.137 0.295 1.390
ENSG00000116337 E018 0.2373413 0.0156965085 4.978354e-01   1 109621074 109621081 8 + 0.137 0.000 -13.179
ENSG00000116337 E019 0.2373413 0.0156965085 4.978354e-01   1 109621082 109621083 2 + 0.137 0.000 -13.179
ENSG00000116337 E020 0.4824864 0.0260992409 6.551231e-01   1 109621084 109621102 19 + 0.192 0.122 -0.780
ENSG00000116337 E021 0.7273794 0.0138685842 8.697426e-01 0.955176102 1 109621103 109621117 15 + 0.241 0.217 -0.195
ENSG00000116337 E022 1.1004812 0.0114355969 6.317707e-01 0.842100655 1 109621118 109621140 23 + 0.285 0.361 0.483
ENSG00000116337 E023 1.1004161 0.0120163350 6.317524e-01 0.842097127 1 109621141 109621151 11 + 0.285 0.361 0.483
ENSG00000116337 E024 1.3541855 0.0284882952 2.421987e-01 0.531892337 1 109621152 109621175 24 + 0.285 0.469 1.068
ENSG00000116337 E025 2.3260173 0.1135879481 4.540274e-01 0.726697193 1 109621176 109621231 56 + 0.455 0.592 0.653
ENSG00000116337 E026 1.7084345 0.0138723955 6.364842e-01 0.844885635 1 109621232 109621266 35 + 0.395 0.469 0.390
ENSG00000116337 E027 0.2451451 0.0164942825 6.680378e-01   1 109621269 109621345 77 + 0.074 0.122 0.805
ENSG00000116337 E028 0.1265070 0.0123691621 3.008840e-01   1 109621346 109621422 77 + 0.000 0.122 12.611
ENSG00000116337 E029 1.6145336 0.0719136164 3.062125e-02 0.164658693 1 109622185 109622353 169 + 0.241 0.592 1.974
ENSG00000116337 E030 0.1272623 0.0123402893 3.010003e-01   1 109623814 109623838 25 + 0.000 0.122 12.611
ENSG00000116337 E031 0.8604031 0.0126248719 2.746277e-01 0.568152015 1 109623839 109623978 140 + 0.192 0.361 1.220
ENSG00000116337 E032 0.6155101 0.0223336139 2.946765e-01 0.587957524 1 109623979 109624038 60 + 0.137 0.295 1.390
ENSG00000116337 E033 0.6253601 0.0476707996 5.450818e-02 0.232564215 1 109624039 109624089 51 + 0.074 0.361 2.805
ENSG00000116337 E034 16.3698136 0.0083322763 9.203995e-01 0.975214559 1 109625303 109625433 131 + 1.224 1.235 0.040
ENSG00000116337 E035 0.0000000       1 109625598 109625661 64 +      
ENSG00000116337 E036 14.3214735 0.0009780287 7.260460e-01 0.890291177 1 109625662 109625792 131 + 1.162 1.192 0.107
ENSG00000116337 E037 0.1186381 0.0118206623 1.000000e+00   1 109625793 109625805 13 + 0.074 0.000 -12.261
ENSG00000116337 E038 0.1265070 0.0123691621 3.008840e-01   1 109626071 109626159 89 + 0.000 0.122 12.611
ENSG00000116337 E039 11.1221415 0.0024346697 4.337869e-01 0.711061787 1 109626160 109626228 69 + 1.096 1.030 -0.242
ENSG00000116337 E040 0.2459655 0.0164204341 6.684321e-01   1 109626229 109626318 90 + 0.074 0.122 0.805
ENSG00000116337 E041 17.4409882 0.0010216812 7.850492e-03 0.068247653 1 109626319 109626427 109 + 1.318 1.124 -0.689
ENSG00000116337 E042 0.1176306 0.0117964631 1.000000e+00   1 109626428 109626725 298 + 0.074 0.000 -12.261
ENSG00000116337 E043 30.5645961 0.0005240659 5.153734e-02 0.225161204 1 109626726 109626912 187 + 1.524 1.419 -0.361
ENSG00000116337 E044 8.9950429 0.0017388037 3.086876e-04 0.005933270 1 109626913 109627174 262 + 0.829 1.164 1.243
ENSG00000116337 E045 23.6422388 0.0006738318 7.339879e-02 0.275492881 1 109627175 109627316 142 + 1.334 1.445 0.386
ENSG00000116337 E046 1.0055130 0.0131498027 3.151203e-03 0.035787955 1 109627317 109627330 14 + 0.074 0.514 3.612
ENSG00000116337 E047 1.1159389 0.0116298777 7.083420e-02 0.269476747 1 109627331 109627412 82 + 0.192 0.469 1.805
ENSG00000116337 E048 0.7353155 0.0142672879 5.074332e-01 0.765878480 1 109627413 109627428 16 + 0.192 0.295 0.805
ENSG00000116337 E049 22.6740118 0.0006602249 9.519966e-01 0.987911698 1 109627429 109627518 90 + 1.362 1.362 -0.002
ENSG00000116337 E050 11.4618154 0.0012284642 1.452236e-01 0.405527566 1 109627774 109627777 4 + 1.127 1.003 -0.454
ENSG00000116337 E051 24.1823480 0.0005830019 1.709711e-01 0.443379451 1 109627778 109627903 126 + 1.418 1.337 -0.282
ENSG00000116337 E052 22.3674014 0.0006886697 2.344501e-01 0.523528196 1 109628083 109628214 132 + 1.383 1.310 -0.254
ENSG00000116337 E053 13.5175194 0.0029934852 2.240208e-01 0.511643728 1 109628215 109628277 63 + 1.109 1.210 0.360
ENSG00000116337 E054 4.2904371 0.0032757261 7.652357e-02 0.282887363 1 109628278 109628363 86 + 0.618 0.834 0.887
ENSG00000116337 E055 7.3287706 0.0051726543 1.207476e-01 0.367579688 1 109628364 109628368 5 + 0.840 1.003 0.612
ENSG00000116337 E056 7.0836228 0.0025361750 1.243784e-01 0.373738023 1 109628369 109628378 10 + 0.829 0.988 0.606
ENSG00000116337 E057 6.0860423 0.0391152765 5.420814e-01 0.789496130 1 109628379 109628495 117 + 0.804 0.892 0.340
ENSG00000116337 E058 0.0000000       1 109628496 109628533 38 +      
ENSG00000116337 E059 0.0000000       1 109628534 109628626 93 +      
ENSG00000116337 E060 0.0000000       1 109628627 109628642 16 +      
ENSG00000116337 E061 0.0000000       1 109628643 109628713 71 +      
ENSG00000116337 E062 0.0000000       1 109628714 109628806 93 +      
ENSG00000116337 E063 1.4764867 0.1903037986 2.006704e-01 0.482758311 1 109628807 109629092 286 + 0.284 0.514 1.292
ENSG00000116337 E064 0.0000000       1 109629093 109629108 16 +      
ENSG00000116337 E065 0.0000000       1 109629109 109629235 127 +      
ENSG00000116337 E066 0.0000000       1 109629236 109629326 91 +      
ENSG00000116337 E067 24.6236036 0.0006531120 9.119790e-01 0.972022892 1 109629327 109629486 160 + 1.393 1.403 0.034
ENSG00000116337 E068 10.7980488 0.0016169385 9.225644e-01 0.976136574 1 109629487 109629490 4 + 1.056 1.067 0.042
ENSG00000116337 E069 1.9398633 0.0076757913 9.407572e-01 0.983232474 1 109629491 109629795 305 + 0.455 0.469 0.068
ENSG00000116337 E070 11.1707704 0.0096149061 7.920148e-01 0.920524724 1 109629796 109629799 4 + 1.063 1.091 0.101
ENSG00000116337 E071 16.8623297 0.0051922249 8.532275e-01 0.948218790 1 109629800 109629916 117 + 1.233 1.251 0.063
ENSG00000116337 E072 17.6248802 0.0103608591 1.499616e-01 0.412482056 1 109630233 109630406 174 + 1.299 1.183 -0.408
ENSG00000116337 E073 0.1187032 0.0118374551 1.000000e+00   1 109630407 109630439 33 + 0.074 0.000 -12.261
ENSG00000116337 E074 0.0000000       1 109630638 109630682 45 +      
ENSG00000116337 E075 23.4291161 0.0005936787 8.635485e-05 0.002106496 1 109630683 109630793 111 + 1.456 1.201 -0.891
ENSG00000116337 E076 149.3740226 0.0001605027 7.532958e-01 0.902898822 1 109630943 109632051 1109 + 2.166 2.162 -0.013

Help

Please Click HERE to learn more details about the results from DEXseq.