ENSG00000116350

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373795 ENSG00000116350 No_inf pgKDN_inf SRSF4 protein_coding protein_coding 42.98165 46.9077 39.58685 0.7883093 1.780954 -0.2447468 23.092596 14.877422 27.750398 3.7073387 2.2071392 0.8989343 0.55387500 0.319650 0.708050 0.388400 0.01209627 0.01209627 FALSE TRUE
MSTRG.576.2 ENSG00000116350 No_inf pgKDN_inf SRSF4 protein_coding   42.98165 46.9077 39.58685 0.7883093 1.780954 -0.2447468 3.314037 6.530831 1.053424 0.9494436 0.7620838 -2.6207564 0.07415833 0.138425 0.029125 -0.109300 0.11546055 0.01209627 FALSE TRUE
MSTRG.576.5 ENSG00000116350 No_inf pgKDN_inf SRSF4 protein_coding   42.98165 46.9077 39.58685 0.7883093 1.780954 -0.2447468 9.941597 18.280696 5.175421 3.1183566 3.1733352 -1.8185770 0.21911667 0.388875 0.123175 -0.265700 0.27007552 0.01209627 FALSE TRUE
MSTRG.576.9 ENSG00000116350 No_inf pgKDN_inf SRSF4 protein_coding   42.98165 46.9077 39.58685 0.7883093 1.780954 -0.2447468 2.617465 3.603908 2.086074 0.6756050 0.2013558 -0.7858703 0.06026667 0.076250 0.053325 -0.022925 0.83437237 0.01209627 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116350 E001 0.2346346 0.0156796905 0.163791698   1 29147743 29147746 4 - 0.193 0.000 -10.645
ENSG00000116350 E002 0.2346346 0.0156796905 0.163791698   1 29147747 29147751 5 - 0.193 0.000 -12.795
ENSG00000116350 E003 0.6052793 0.2126314698 0.495400232 0.75658710 1 29147752 29147760 9 - 0.264 0.155 -0.962
ENSG00000116350 E004 1.0867582 0.1634219534 0.206689041 0.49032623 1 29147761 29147762 2 - 0.427 0.216 -1.377
ENSG00000116350 E005 2.4302134 0.1592809482 0.214893528 0.50049953 1 29147763 29147777 15 - 0.638 0.434 -0.963
ENSG00000116350 E006 13.5995100 0.0013550397 0.195307759 0.47556337 1 29147778 29147852 75 - 1.213 1.115 -0.351
ENSG00000116350 E007 205.6329607 0.0001329557 0.507070882 0.76563590 1 29147853 29148670 818 - 2.301 2.315 0.047
ENSG00000116350 E008 133.0691067 0.0002136776 0.689603009 0.87242259 1 29148671 29149226 556 - 2.114 2.126 0.039
ENSG00000116350 E009 23.7290737 0.0007732056 0.022293493 0.13580046 1 29150103 29150192 90 - 1.461 1.326 -0.466
ENSG00000116350 E010 0.1187032 0.0118160982 0.410398103   1 29154475 29154695 221 - 0.107 0.000 -11.863
ENSG00000116350 E011 15.4592661 0.0008988335 0.437002138 0.71344210 1 29154696 29154696 1 - 1.242 1.187 -0.194
ENSG00000116350 E012 25.0789501 0.0005230558 0.721968545 0.88819587 1 29154697 29154735 39 - 1.421 1.403 -0.065
ENSG00000116350 E013 45.2037009 0.0004263489 0.268719559 0.56229372 1 29154736 29154871 136 - 1.685 1.639 -0.157
ENSG00000116350 E014 20.3706870 0.0007164488 0.348939860 0.63949582 1 29154872 29154910 39 - 1.357 1.299 -0.203
ENSG00000116350 E015 35.7827910 0.0008494154 0.041931645 0.19925474 1 29159374 29159486 113 - 1.615 1.516 -0.338
ENSG00000116350 E016 2.9411652 0.0721910608 0.591140378 0.81916100 1 29159487 29159863 377 - 0.638 0.554 -0.378
ENSG00000116350 E017 3.4060582 0.0064837673 0.071348601 0.27061290 1 29159864 29160058 195 - 0.759 0.527 -1.005
ENSG00000116350 E018 0.6253903 0.0141510008 0.281836605 0.57521288 1 29160059 29160091 33 - 0.107 0.269 1.623
ENSG00000116350 E019 1.9946579 0.0075505728 0.130873980 0.38374237 1 29160092 29160374 283 - 0.325 0.554 1.208
ENSG00000116350 E020 28.8541672 0.0018524444 0.367887733 0.65648680 1 29160375 29160517 143 - 1.497 1.448 -0.168
ENSG00000116350 E021 1.1091054 0.0197051803 0.949146332 0.98676200 1 29160518 29160563 46 - 0.325 0.317 -0.055
ENSG00000116350 E022 0.7256192 0.0133191506 0.255131109 0.54703988 1 29165207 29165251 45 - 0.325 0.155 -1.377
ENSG00000116350 E023 8.6889805 0.0132161260 0.063470631 0.25351589 1 29165890 29166064 175 - 0.854 1.053 0.748
ENSG00000116350 E024 9.1481492 0.0015192723 0.231134307 0.51963308 1 29166729 29166866 138 - 0.931 1.045 0.423
ENSG00000116350 E025 4.2009409 0.0033414397 0.547097301 0.79262110 1 29166867 29166912 46 - 0.665 0.741 0.315
ENSG00000116350 E026 17.7668229 0.0219238840 0.013679793 0.09854494 1 29166913 29167891 979 - 1.114 1.352 0.840
ENSG00000116350 E027 10.3381341 0.0276650649 0.009928934 0.07987875 1 29168503 29168638 136 - 0.854 1.149 1.094
ENSG00000116350 E028 39.6216438 0.0047985684 0.183114237 0.45978959 1 29168639 29171284 2646 - 1.558 1.632 0.253
ENSG00000116350 E029 17.6478921 0.0109007403 0.380574795 0.66706608 1 29171285 29173494 2210 - 1.221 1.294 0.259
ENSG00000116350 E030 12.5429346 0.0184524393 0.755020847 0.90358940 1 29181646 29181900 255 - 1.141 1.115 -0.094

Help

Please Click HERE to learn more details about the results from DEXseq.