ENSG00000116478

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373548 ENSG00000116478 No_inf pgKDN_inf HDAC1 protein_coding protein_coding 105.3775 115.9568 103.4092 3.010722 0.6021281 -0.1652075 86.990320 90.22644 92.946104 2.8412589 0.6645418 0.04283945 0.82757500 0.777875 0.898825 0.120950 1.452758e-07 1.452758e-07 FALSE TRUE
ENST00000476391 ENSG00000116478 No_inf pgKDN_inf HDAC1 protein_coding retained_intron 105.3775 115.9568 103.4092 3.010722 0.6021281 -0.1652075 7.159899 11.37836 4.597635 0.2970185 0.3165492 -1.30546130 0.06655833 0.098450 0.044475 -0.053975 8.095238e-02 1.452758e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116478 E001 9.628611 1.651985e-03 4.210809e-02 1.996885e-01 1 32292083 32292134 52 + 1.116 0.934 -0.669
ENSG00000116478 E002 11.604043 1.186063e-03 1.096703e-01 3.475557e-01 1 32292135 32292136 2 + 1.167 1.035 -0.477
ENSG00000116478 E003 13.461148 9.802950e-04 2.520194e-01 5.433054e-01 1 32292137 32292139 3 + 1.205 1.116 -0.317
ENSG00000116478 E004 22.652556 6.195445e-04 1.880426e-01 4.662874e-01 1 32292140 32292160 21 + 1.414 1.333 -0.280
ENSG00000116478 E005 64.660448 2.366572e-04 3.360465e-02 1.743730e-01 1 32292161 32292218 58 + 1.856 1.778 -0.264
ENSG00000116478 E006 110.071875 1.627471e-04 3.638550e-03 3.978944e-02 1 32302621 32302733 113 + 2.086 2.005 -0.274
ENSG00000116478 E007 101.169418 1.702758e-04 7.265779e-03 6.470815e-02 1 32316665 32316782 118 + 2.048 1.970 -0.264
ENSG00000116478 E008 67.885091 1.005002e-03 5.192769e-01 7.740287e-01 1 32324479 32324553 75 + 1.848 1.824 -0.081
ENSG00000116478 E009 89.904598 6.402202e-04 1.808777e-02 1.186651e-01 1 32326939 32327077 139 + 1.996 1.920 -0.256
ENSG00000116478 E010 4.431160 1.424423e-02 9.113011e-01 9.717870e-01 1 32327078 32327188 111 + 0.724 0.738 0.058
ENSG00000116478 E011 2.966203 1.243311e-02 4.514018e-01 7.244942e-01 1 32327189 32327273 85 + 0.533 0.639 0.473
ENSG00000116478 E012 5.269843 3.042493e-03 9.714527e-05 2.315260e-03 1 32327274 32327405 132 + 0.459 0.945 2.058
ENSG00000116478 E013 3.907500 1.417770e-02 3.028446e-05 8.720565e-04 1 32327406 32327458 53 + 0.256 0.861 2.958
ENSG00000116478 E014 2.629086 5.378377e-03 1.210837e-02 9.107940e-02 1 32327459 32327535 77 + 0.317 0.681 1.823
ENSG00000116478 E015 70.741273 6.877252e-03 7.664891e-01 9.093869e-01 1 32327536 32327677 142 + 1.859 1.847 -0.043
ENSG00000116478 E016 63.636907 2.721939e-04 7.377623e-01 8.959078e-01 1 32329068 32329160 93 + 1.814 1.802 -0.041
ENSG00000116478 E017 26.754125 4.886811e-04 1.541283e-07 8.587560e-06 1 32329480 32330148 669 + 1.233 1.552 1.105
ENSG00000116478 E018 21.232532 3.226360e-03 1.453665e-04 3.219793e-03 1 32330149 32330577 429 + 1.175 1.441 0.930
ENSG00000116478 E019 63.848121 2.868477e-04 5.551855e-01 7.977846e-01 1 32330578 32330662 85 + 1.795 1.818 0.077
ENSG00000116478 E020 40.151924 4.049139e-04 6.172425e-01 8.342626e-01 1 32330663 32330686 24 + 1.624 1.601 -0.079
ENSG00000116478 E021 121.701887 1.696596e-04 6.965740e-01 8.760960e-01 1 32330768 32330908 141 + 2.091 2.081 -0.034
ENSG00000116478 E022 87.739605 1.836270e-04 8.655628e-01 9.536934e-01 1 32331474 32331535 62 + 1.941 1.947 0.020
ENSG00000116478 E023 70.527806 2.118238e-04 9.555990e-01 9.892828e-01 1 32331536 32331582 47 + 1.850 1.852 0.008
ENSG00000116478 E024 100.908954 1.509755e-04 4.449404e-01 7.194980e-01 1 32331676 32331806 131 + 2.017 1.995 -0.074
ENSG00000116478 E025 2.511386 5.814220e-03 4.153490e-03 4.363744e-02 1 32331807 32332089 283 + 0.256 0.681 2.238
ENSG00000116478 E026 98.047877 2.507718e-04 8.477380e-01 9.460160e-01 1 32332090 32332242 153 + 1.995 1.990 -0.018
ENSG00000116478 E027 78.398380 2.105822e-04 3.251847e-01 6.177054e-01 1 32332701 32332749 49 + 1.877 1.911 0.114
ENSG00000116478 E028 332.435972 8.137348e-05 2.105266e-04 4.363774e-03 1 32333017 32333635 619 + 2.486 2.544 0.192

Help

Please Click HERE to learn more details about the results from DEXseq.