ENSG00000116521

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302631 ENSG00000116521 No_inf pgKDN_inf SCAMP3 protein_coding protein_coding 110.2516 74.89306 118.6204 2.809783 1.645641 0.6633776 50.110343 24.73491 56.34727 3.014039 5.606792 1.18747000 0.4372750 0.332275 0.475125 0.142850 3.334950e-01 6.813324e-13 FALSE TRUE
ENST00000355379 ENSG00000116521 No_inf pgKDN_inf SCAMP3 protein_coding protein_coding 110.2516 74.89306 118.6204 2.809783 1.645641 0.6633776 23.629703 14.31250 32.70915 2.634803 4.434108 1.19185152 0.2139083 0.191225 0.275775 0.084550 5.964789e-01 6.813324e-13 FALSE TRUE
ENST00000478737 ENSG00000116521 No_inf pgKDN_inf SCAMP3 protein_coding protein_coding_CDS_not_defined 110.2516 74.89306 118.6204 2.809783 1.645641 0.6633776 20.115081 14.52844 13.63934 4.133446 2.440336 -0.09104126 0.1790667 0.188900 0.114325 -0.074575 6.142425e-01 6.813324e-13 FALSE FALSE
ENST00000490999 ENSG00000116521 No_inf pgKDN_inf SCAMP3 protein_coding protein_coding_CDS_not_defined 110.2516 74.89306 118.6204 2.809783 1.645641 0.6633776 3.630944 10.89283 0.00000 2.218571 0.000000 -10.09048711 0.0496750 0.149025 0.000000 -0.149025 6.813324e-13 6.813324e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116521 E001 0.2452102 0.0165338351 7.128308e-01   1 155255979 155255979 1 - 0.077 0.117 0.683
ENSG00000116521 E002 0.2452102 0.0165338351 7.128308e-01   1 155255980 155255980 1 - 0.077 0.117 0.683
ENSG00000116521 E003 0.2452102 0.0165338351 7.128308e-01   1 155255981 155255984 4 - 0.077 0.117 0.683
ENSG00000116521 E004 3.6276953 0.0053312313 5.723203e-01 0.808353755 1 155255985 155256006 22 - 0.687 0.613 -0.317
ENSG00000116521 E005 81.7558008 0.0002534215 4.322457e-01 0.709672446 1 155256007 155256240 234 - 1.920 1.893 -0.088
ENSG00000116521 E006 113.5787859 0.0001433347 7.171777e-01 0.886085037 1 155256241 155256419 179 - 2.046 2.056 0.033
ENSG00000116521 E007 98.1297739 0.0001790670 2.241058e-01 0.511715048 1 155256674 155256791 118 - 1.973 2.009 0.122
ENSG00000116521 E008 38.9085478 0.0018446190 5.005389e-01 0.760581036 1 155257285 155257285 1 - 1.579 1.613 0.117
ENSG00000116521 E009 43.1746248 0.0040877392 4.651937e-01 0.734348639 1 155257286 155257297 12 - 1.621 1.660 0.132
ENSG00000116521 E010 64.4402742 0.0003109732 3.866290e-01 0.672527132 1 155257298 155257334 37 - 1.794 1.826 0.109
ENSG00000116521 E011 60.7392576 0.0004785596 1.295036e-01 0.381733374 1 155257335 155257386 52 - 1.757 1.816 0.199
ENSG00000116521 E012 1.6406585 0.0097369290 5.099297e-05 0.001353472 1 155257424 155257497 74 - 0.077 0.674 4.268
ENSG00000116521 E013 110.1693473 0.0024106879 6.188958e-01 0.835218901 1 155257498 155257657 160 - 2.044 2.027 -0.057
ENSG00000116521 E014 1.7323553 0.0221331265 5.941798e-02 0.244587157 1 155258791 155258825 35 - 0.294 0.579 1.531
ENSG00000116521 E015 66.6226854 0.0024503831 2.331321e-01 0.521880484 1 155258826 155258892 67 - 1.841 1.791 -0.170
ENSG00000116521 E016 46.1950319 0.0015714438 4.682514e-01 0.736485361 1 155258893 155258912 20 - 1.679 1.645 -0.117
ENSG00000116521 E017 53.3104965 0.0013585435 9.688589e-01 0.993641226 1 155258913 155258954 42 - 1.727 1.725 -0.007
ENSG00000116521 E018 71.7436516 0.0004172067 4.645106e-01 0.733979299 1 155260330 155260450 121 - 1.842 1.869 0.088
ENSG00000116521 E019 1.2528601 0.0617753935 1.202360e-02 0.090620579 1 155260451 155260536 86 - 0.142 0.542 2.683
ENSG00000116521 E020 70.5027173 0.0021166115 5.596585e-01 0.800635458 1 155260537 155260659 123 - 1.836 1.859 0.077
ENSG00000116521 E021 1.4717922 0.0152377260 4.235968e-01 0.702854041 1 155261227 155261656 430 - 0.334 0.456 0.683
ENSG00000116521 E022 32.7777164 0.0014076351 8.524844e-02 0.301982392 1 155261657 155261734 78 - 1.556 1.461 -0.325
ENSG00000116521 E023 0.2457744 0.0165604930 7.129748e-01   1 155261735 155261868 134 - 0.077 0.117 0.683
ENSG00000116521 E024 0.9981800 0.0189048804 3.862032e-02 0.190102064 1 155261946 155262085 140 - 0.142 0.456 2.268
ENSG00000116521 E025 72.0941195 0.0008023598 5.493471e-04 0.009396007 1 155262086 155262430 345 - 1.903 1.773 -0.438

Help

Please Click HERE to learn more details about the results from DEXseq.