ENSG00000116604

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360595 ENSG00000116604 No_inf pgKDN_inf MEF2D protein_coding protein_coding 119.0463 85.36748 134.4316 1.424733 2.146003 0.6550516 57.73312 29.7882647 69.77679 1.453254 1.464352 1.2277257 0.46823333 0.348975 0.519550 0.170575 0.0023402374 0.0007167771 FALSE TRUE
ENST00000489057 ENSG00000116604 No_inf pgKDN_inf MEF2D protein_coding protein_coding 119.0463 85.36748 134.4316 1.424733 2.146003 0.6550516 10.25441 0.8268685 18.38552 0.579766 2.764136 4.4582093 0.07629167 0.009700 0.135925 0.126225 0.0007167771 0.0007167771 TRUE FALSE
MSTRG.2006.1 ENSG00000116604 No_inf pgKDN_inf MEF2D protein_coding   119.0463 85.36748 134.4316 1.424733 2.146003 0.6550516 16.29863 14.0630570 17.29864 1.506547 1.812161 0.2985565 0.14047500 0.164875 0.128950 -0.035925 0.7848565630 0.0007167771 FALSE TRUE
MSTRG.2006.3 ENSG00000116604 No_inf pgKDN_inf MEF2D protein_coding   119.0463 85.36748 134.4316 1.424733 2.146003 0.6550516 25.91224 30.9649128 25.89103 2.564259 3.206821 -0.2580907 0.23585833 0.362650 0.192925 -0.169725 0.0235589013 0.0007167771 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116604 E001 0.2539903 0.0160303561 2.035509e-01   1 156463624 156463726 103 - 0.000 0.181 10.669
ENSG00000116604 E002 1.5933292 0.0169203079 6.297761e-01 8.411934e-01 1 156463727 156463729 3 - 0.378 0.449 0.388
ENSG00000116604 E003 609.8142950 0.0000768897 2.183209e-61 6.197327e-58 1 156463730 156466209 2480 - 2.685 2.870 0.616
ENSG00000116604 E004 782.8986472 0.0000543286 6.361612e-01 8.448419e-01 1 156466210 156467627 1418 - 2.893 2.895 0.005
ENSG00000116604 E005 71.8609596 0.0046255651 7.020661e-03 6.316136e-02 1 156467628 156467656 29 - 1.919 1.794 -0.424
ENSG00000116604 E006 42.4105238 0.0013952728 7.569784e-01 9.043499e-01 1 156467657 156467992 336 - 1.632 1.644 0.040
ENSG00000116604 E007 220.1955217 0.0011071833 3.065048e-02 1.647302e-01 1 156467993 156468299 307 - 2.370 2.316 -0.182
ENSG00000116604 E008 140.5602717 0.0001835477 2.364161e-01 5.254313e-01 1 156468780 156469020 241 - 2.167 2.134 -0.111
ENSG00000116604 E009 117.3751734 0.0001476300 3.077610e-02 1.650799e-01 1 156475108 156475237 130 - 2.103 2.040 -0.211
ENSG00000116604 E010 2.7386238 0.0058877402 1.571298e-02 1.084630e-01 1 156476494 156476514 21 - 0.378 0.712 1.580
ENSG00000116604 E011 1.3785801 0.0100923370 1.828743e-02 1.194664e-01 1 156476929 156477011 83 - 0.165 0.523 2.335
ENSG00000116604 E012 144.2597550 0.0014232169 1.102234e-01 3.483973e-01 1 156477012 156477202 191 - 2.186 2.136 -0.165
ENSG00000116604 E013 66.5821942 0.0056255872 3.129944e-01 6.063377e-01 1 156479290 156479346 57 - 1.854 1.803 -0.175
ENSG00000116604 E014 133.5895780 0.0017352714 3.797235e-04 7.013701e-03 1 156479586 156479796 211 - 2.180 2.068 -0.377
ENSG00000116604 E015 2.6126178 0.0060555957 2.524189e-02 1.462072e-01 1 156480643 156480777 135 - 0.378 0.689 1.487
ENSG00000116604 E016 92.6884466 0.0002705611 4.558702e-06 1.736363e-04 1 156480834 156480971 138 - 2.038 1.889 -0.501
ENSG00000116604 E017 123.3568003 0.0001916138 6.603205e-05 1.670475e-03 1 156482437 156482640 204 - 2.146 2.034 -0.376
ENSG00000116604 E018 46.8953615 0.0050723594 1.271169e-01 3.780032e-01 1 156483239 156483260 22 - 1.719 1.636 -0.281
ENSG00000116604 E019 99.7943822 0.0029347583 3.686198e-04 6.863241e-03 1 156483261 156483418 158 - 2.065 1.928 -0.460
ENSG00000116604 E020 31.7857185 0.0004308509 8.173946e-04 1.283417e-02 1 156483419 156483430 12 - 1.595 1.413 -0.625
ENSG00000116604 E021 0.8879746 0.0124533231 2.783367e-03 3.262019e-02 1 156490512 156490599 88 - 0.000 0.449 14.450
ENSG00000116604 E022 4.1020860 0.0038844886 3.960850e-02 1.929935e-01 1 156499432 156499560 129 - 0.816 0.555 -1.098
ENSG00000116604 E023 104.1182103 0.0007558735 4.283349e-06 1.646601e-04 1 156500486 156500829 344 - 2.088 1.940 -0.496

Help

Please Click HERE to learn more details about the results from DEXseq.