ENSG00000116691

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000235332 ENSG00000116691 No_inf pgKDN_inf MIIP protein_coding protein_coding 23.00803 18.86702 20.67501 0.9134042 0.8015447 0.1319545 14.3167533 10.838422 13.758255 0.4687074 1.1009020 0.3438604 0.6190000 0.575400 0.662925 0.087525 0.680481003 0.002862021 FALSE  
ENST00000466860 ENSG00000116691 No_inf pgKDN_inf MIIP protein_coding protein_coding_CDS_not_defined 23.00803 18.86702 20.67501 0.9134042 0.8015447 0.1319545 2.7263721 3.231937 2.069064 1.0625925 0.6008434 -0.6409216 0.1205833 0.166025 0.098025 -0.068000 0.819533172 0.002862021 TRUE  
ENST00000492256 ENSG00000116691 No_inf pgKDN_inf MIIP protein_coding protein_coding_CDS_not_defined 23.00803 18.86702 20.67501 0.9134042 0.8015447 0.1319545 0.6270145 1.430838 0.000000 0.3825052 0.0000000 -7.1707638 0.0293250 0.073550 0.000000 -0.073550 0.002862021 0.002862021    
MSTRG.252.2 ENSG00000116691 No_inf pgKDN_inf MIIP protein_coding   23.00803 18.86702 20.67501 0.9134042 0.8015447 0.1319545 3.7675343 1.454754 3.343450 1.1243335 1.1507055 1.1949874 0.1593583 0.086675 0.166075 0.079400 0.719690995 0.002862021 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116691 E001 0.126507 0.0122812176 0.522143941   1 12019466 12019494 29 + 0.000 0.096 10.355
ENSG00000116691 E002 0.243511 0.0162368975 0.981509578   1 12019495 12019497 3 + 0.094 0.096 0.046
ENSG00000116691 E003 5.387088 0.0026871020 0.920459636 0.97521456 1 12019498 12019552 55 + 0.799 0.811 0.046
ENSG00000116691 E004 20.581132 0.0007989599 0.073385720 0.27549143 1 12021645 12021840 196 + 1.387 1.277 -0.384
ENSG00000116691 E005 16.516653 0.0008434703 0.013425180 0.09733481 1 12022095 12022221 127 + 1.322 1.152 -0.601
ENSG00000116691 E006 20.170510 0.0049092463 0.018049202 0.11855538 1 12022222 12022442 221 + 1.400 1.241 -0.554
ENSG00000116691 E007 5.278478 0.0070407804 0.584832683 0.81546965 1 12022833 12022863 31 + 0.765 0.827 0.247
ENSG00000116691 E008 6.590306 0.0028657289 0.479102519 0.74499845 1 12022864 12022917 54 + 0.915 0.843 -0.276
ENSG00000116691 E009 1.514593 0.0097585997 0.001738008 0.02289082 1 12028721 12029032 312 + 0.094 0.572 3.505
ENSG00000116691 E010 9.998824 0.0014698825 0.327593939 0.62016327 1 12029033 12029095 63 + 1.082 0.998 -0.308
ENSG00000116691 E011 10.268923 0.0013101041 0.762107006 0.90725855 1 12029096 12029141 46 + 1.064 1.039 -0.092
ENSG00000116691 E012 13.997534 0.0011378010 0.356747496 0.64661015 1 12029223 12029281 59 + 1.139 1.209 0.248
ENSG00000116691 E013 17.735948 0.0007944593 0.038224500 0.18875665 1 12029282 12029764 483 + 1.196 1.335 0.490
ENSG00000116691 E014 20.868957 0.0016893928 0.331216606 0.62351960 1 12029765 12029894 130 + 1.307 1.369 0.216
ENSG00000116691 E015 4.446935 0.0113570022 0.171610087 0.44421283 1 12029895 12030027 133 + 0.641 0.811 0.698
ENSG00000116691 E016 20.624822 0.0007334250 0.317878962 0.61063468 1 12030028 12030124 97 + 1.302 1.364 0.218
ENSG00000116691 E017 0.126854 0.0123706617 0.522013810   1 12031127 12031265 139 + 0.000 0.096 10.357
ENSG00000116691 E018 23.776589 0.0006878320 0.605219999 0.82795678 1 12031266 12031403 138 + 1.378 1.409 0.105
ENSG00000116691 E019 1.844134 0.0084016951 0.756095557 0.90385821 1 12031541 12031721 181 + 0.429 0.476 0.238
ENSG00000116691 E020 21.824228 0.0006696262 0.603385108 0.82699604 1 12031722 12032045 324 + 1.342 1.373 0.110

Help

Please Click HERE to learn more details about the results from DEXseq.