ENSG00000116985

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372827 ENSG00000116985 No_inf pgKDN_inf BMP8B protein_coding protein_coding 168.6213 240.9869 157.0499 0.4259183 1.066847 -0.6176993 92.82534 112.3030 95.73715 2.554857 3.225864 -0.2302236 0.5762917 0.466025 0.609625 0.143600 0.003080864 0.002234693 FALSE TRUE
MSTRG.756.2 ENSG00000116985 No_inf pgKDN_inf BMP8B protein_coding   168.6213 240.9869 157.0499 0.4259183 1.066847 -0.6176993 68.00400 118.1229 53.50714 2.273700 3.191160 -1.1423378 0.3770500 0.490175 0.340600 -0.149575 0.002234693 0.002234693 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000116985 E001 0.4893505 1.609965e-02 5.703725e-01   1 39756774 39756775 2 - 0.218 0.136 -0.824
ENSG00000116985 E002 4.1059749 6.704540e-03 2.959438e-01 5.890109e-01 1 39756776 39756784 9 - 0.595 0.734 0.591
ENSG00000116985 E003 109.5978791 3.594382e-04 5.795575e-02 2.409552e-01 1 39756785 39757181 397 - 1.981 2.042 0.203
ENSG00000116985 E004 4349.5119522 3.106679e-05 1.344272e-21 4.190866e-19 1 39757182 39760568 3387 - 3.606 3.622 0.051
ENSG00000116985 E005 86.3103027 1.828098e-04 2.500744e-06 1.028012e-04 1 39763092 39763202 111 - 2.014 1.860 -0.519
ENSG00000116985 E006 0.0000000       1 39763712 39763791 80 -      
ENSG00000116985 E007 32.1277348 2.124215e-03 1.053637e-04 2.477194e-03 1 39764623 39764732 110 - 1.627 1.412 -0.736
ENSG00000116985 E008 11.0367555 3.361965e-03 1.603181e-02 1.098070e-01 1 39764733 39764817 85 - 1.186 0.976 -0.760
ENSG00000116985 E009 7.2937286 1.873949e-03 8.424953e-01 9.435821e-01 1 39764849 39765008 160 - 0.912 0.892 -0.074
ENSG00000116985 E010 0.0000000       1 39774308 39774425 118 -      
ENSG00000116985 E011 0.0000000       1 39774426 39774456 31 -      
ENSG00000116985 E012 22.6053073 7.675938e-04 5.326589e-03 5.185637e-02 1 39774849 39775038 190 - 1.458 1.284 -0.604
ENSG00000116985 E013 157.1954737 1.154538e-04 3.457490e-22 1.151088e-19 1 39788152 39788865 714 - 2.316 2.082 -0.782

Help

Please Click HERE to learn more details about the results from DEXseq.