ENSG00000117000

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372771 ENSG00000117000 No_inf pgKDN_inf RLF protein_coding protein_coding 78.49752 66.18361 89.27684 1.207219 0.9890669 0.4317556 49.18704 32.28192 59.96797 1.815702 3.024018 0.8932594 0.6173917 0.48915 0.671725 0.182575 0.04388263 0.04388263 FALSE TRUE
MSTRG.766.2 ENSG00000117000 No_inf pgKDN_inf RLF protein_coding   78.49752 66.18361 89.27684 1.207219 0.9890669 0.4317556 29.31048 33.90169 29.30887 2.737547 2.998349 -0.2099532 0.3826083 0.51085 0.328275 -0.182575 0.06599109 0.04388263 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000117000 E001 0.9599715 1.169327e-02 2.371544e-01 5.261381e-01 1 40161387 40161388 2 + 0.369 0.187 -1.319
ENSG00000117000 E002 40.6842862 3.585646e-04 7.919371e-03 6.865831e-02 1 40161389 40161636 248 + 1.674 1.548 -0.428
ENSG00000117000 E003 39.2267149 3.561557e-04 7.899516e-05 1.950790e-03 1 40189055 40189209 155 + 1.684 1.492 -0.655
ENSG00000117000 E004 23.2415716 3.458462e-03 5.790131e-03 5.502071e-02 1 40190772 40190853 82 + 1.461 1.278 -0.634
ENSG00000117000 E005 36.3128610 4.044260e-04 4.598606e-01 7.314749e-01 1 40195632 40195764 133 + 1.588 1.552 -0.124
ENSG00000117000 E006 47.6754869 9.924493e-04 5.788498e-01 8.118088e-01 1 40202412 40202614 203 + 1.698 1.674 -0.083
ENSG00000117000 E007 35.1652747 6.144813e-04 1.505488e-01 4.131112e-01 1 40222574 40222710 137 + 1.590 1.518 -0.249
ENSG00000117000 E008 33.5159206 4.149657e-04 1.920587e-02 1.237426e-01 1 40231517 40231658 142 + 1.590 1.469 -0.416
ENSG00000117000 E009 2276.2886390 3.487658e-05 9.441921e-09 6.762823e-07 1 40235792 40241008 5217 + 3.351 3.363 0.041

Help

Please Click HERE to learn more details about the results from DEXseq.