ENSG00000117139

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000472822 ENSG00000117139 No_inf pgKDN_inf KDM5B protein_coding retained_intron 19.71521 21.77427 19.26299 0.8814265 1.238454 -0.1767063 0.8786848 1.354033 0.1269016 0.7940188 0.1269016 -3.3166677 0.04483333 0.06550 0.006075 -0.059425 0.78362284 0.03373008 FALSE TRUE
ENST00000647657 ENSG00000117139 No_inf pgKDN_inf KDM5B protein_coding retained_intron 19.71521 21.77427 19.26299 0.8814265 1.238454 -0.1767063 2.1996281 1.401657 3.3904037 0.8867055 1.3328220 1.2683162 0.10710833 0.06200 0.164900 0.102900 0.71549027 0.03373008 FALSE TRUE
ENST00000649542 ENSG00000117139 No_inf pgKDN_inf KDM5B protein_coding protein_coding_CDS_not_defined 19.71521 21.77427 19.26299 0.8814265 1.238454 -0.1767063 6.7877439 6.263861 7.2850551 1.7494214 0.4523817 0.2175652 0.34838333 0.27995 0.382475 0.102525 0.75491938 0.03373008 FALSE TRUE
ENST00000650569 ENSG00000117139 No_inf pgKDN_inf KDM5B protein_coding protein_coding 19.71521 21.77427 19.26299 0.8814265 1.238454 -0.1767063 1.2294479 0.000000 2.2842339 0.0000000 1.0206817 7.8418687 0.06553333 0.00000 0.115050 0.115050 0.03373008 0.03373008 FALSE TRUE
MSTRG.2537.14 ENSG00000117139 No_inf pgKDN_inf KDM5B protein_coding   19.71521 21.77427 19.26299 0.8814265 1.238454 -0.1767063 4.4495078 6.786376 4.0134748 1.5141048 1.5353589 -0.7563238 0.22659167 0.32145 0.217350 -0.104100 0.82909338 0.03373008 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000117139 E001 0.1187032 0.0117903869 0.4636590108   1 202724495 202724713 219 - 0.101 0.000 -10.824
ENSG00000117139 E002 0.1187032 0.0117903869 0.4636590108   1 202724714 202724886 173 - 0.101 0.000 -13.827
ENSG00000117139 E003 2.1075027 0.0484531441 0.4031166904 0.686139287 1 202724887 202726503 1617 - 0.411 0.545 0.670
ENSG00000117139 E004 1.2325323 0.0139035586 0.6925229094 0.874189747 1 202726504 202727403 900 - 0.312 0.374 0.381
ENSG00000117139 E005 0.0000000       1 202727404 202727404 1 -      
ENSG00000117139 E006 0.3720642 0.0165858977 0.6794929569   1 202727405 202727411 7 - 0.101 0.163 0.796
ENSG00000117139 E007 0.3720642 0.0165858977 0.6794929569   1 202727412 202727416 5 - 0.101 0.163 0.796
ENSG00000117139 E008 0.3720642 0.0165858977 0.6794929569   1 202727417 202727426 10 - 0.101 0.163 0.796
ENSG00000117139 E009 0.8699712 0.0280757297 0.3481150749 0.638570113 1 202727427 202727434 8 - 0.183 0.330 1.118
ENSG00000117139 E010 2.0956994 0.0079907683 0.6760597334 0.865827789 1 202727435 202727444 10 - 0.453 0.516 0.310
ENSG00000117139 E011 2.3487135 0.0428011752 0.4534047856 0.726147993 1 202727445 202727447 3 - 0.453 0.572 0.573
ENSG00000117139 E012 5.6587595 0.0142219750 0.7216344077 0.887959507 1 202727448 202727493 46 - 0.796 0.841 0.174
ENSG00000117139 E013 13.1996978 0.0010815720 0.2052344849 0.488526167 1 202727494 202727582 89 - 1.090 1.193 0.369
ENSG00000117139 E014 17.5241696 0.0010409811 0.1010694122 0.331997810 1 202727583 202727674 92 - 1.196 1.314 0.415
ENSG00000117139 E015 58.0201952 0.0002776901 0.0013502598 0.018881232 1 202727675 202728203 529 - 1.693 1.821 0.432
ENSG00000117139 E016 16.3421348 0.0008170389 0.7840081032 0.916834232 1 202728204 202728290 87 - 1.224 1.247 0.079
ENSG00000117139 E017 22.7875676 0.0006497899 0.3872250786 0.673110432 1 202728291 202728447 157 - 1.401 1.351 -0.173
ENSG00000117139 E018 12.1297184 0.0011670954 0.6657215576 0.860969870 1 202728448 202728480 33 - 1.134 1.101 -0.117
ENSG00000117139 E019 24.6107779 0.0006243046 0.2615578064 0.554323563 1 202728481 202728614 134 - 1.440 1.377 -0.219
ENSG00000117139 E020 20.9134735 0.0007326593 0.4676899985 0.736027323 1 202728615 202728697 83 - 1.311 1.360 0.171
ENSG00000117139 E021 70.3177412 0.0004575753 0.7524509788 0.902459274 1 202728698 202729103 406 - 1.855 1.847 -0.028
ENSG00000117139 E022 13.8500065 0.0020766795 0.4963606543 0.757368816 1 202729104 202729173 70 - 1.196 1.146 -0.179
ENSG00000117139 E023 0.2537694 0.0159926464 0.2973365350   1 202729174 202729474 301 - 0.000 0.163 13.596
ENSG00000117139 E024 0.4890306 0.0553868734 0.8876108930   1 202729475 202729706 232 - 0.183 0.163 -0.204
ENSG00000117139 E025 31.4821534 0.0004569291 0.4840813644 0.748350273 1 202729707 202729904 198 - 1.487 1.526 0.135
ENSG00000117139 E026 23.2537789 0.0006449675 0.4196489476 0.699158114 1 202729905 202730027 123 - 1.353 1.405 0.180
ENSG00000117139 E027 0.1170040 0.0116804719 0.4636869021   1 202730028 202730908 881 - 0.101 0.000 -13.827
ENSG00000117139 E028 22.0315232 0.0008893174 0.2542673269 0.545985620 1 202730909 202731063 155 - 1.396 1.328 -0.236
ENSG00000117139 E029 0.2542726 0.2463471883 0.3535938750   1 202731064 202731827 764 - 0.000 0.163 13.148
ENSG00000117139 E030 17.7933160 0.0034760023 0.9834987505 0.998690264 1 202731828 202731939 112 - 1.270 1.274 0.015
ENSG00000117139 E031 2.1124121 0.0066623783 0.1599594892 0.427527136 1 202731940 202733400 1461 - 0.364 0.572 1.059
ENSG00000117139 E032 50.7931761 0.0004811667 0.7400147767 0.896869909 1 202733401 202733886 486 - 1.718 1.707 -0.037
ENSG00000117139 E033 1.1947999 0.0180583760 0.0320700280 0.169342558 1 202733887 202734315 429 - 0.492 0.163 -2.204
ENSG00000117139 E034 0.3706473 0.0165362944 0.6791599770   1 202735172 202735428 257 - 0.101 0.163 0.796
ENSG00000117139 E035 7.7371276 0.0018282679 0.9659099538 0.993003311 1 202735429 202735504 76 - 0.935 0.942 0.025
ENSG00000117139 E036 11.2870810 0.0014147255 0.7702717321 0.911449769 1 202735505 202735587 83 - 1.099 1.077 -0.079
ENSG00000117139 E037 19.3195954 0.0008002686 0.4526714012 0.725745922 1 202736213 202736392 180 - 1.276 1.328 0.184
ENSG00000117139 E038 14.8903576 0.0149442312 0.5309295807 0.781719218 1 202740674 202740812 139 - 1.166 1.224 0.204
ENSG00000117139 E039 13.9419951 0.0141565310 0.3975047420 0.681664200 1 202741367 202741545 179 - 1.210 1.139 -0.255
ENSG00000117139 E040 12.5486223 0.0131548182 0.7087636934 0.881957170 1 202741546 202741722 177 - 1.108 1.146 0.137
ENSG00000117139 E041 11.0370894 0.0012961606 0.6248280443 0.838580310 1 202742391 202742505 115 - 1.099 1.060 -0.140
ENSG00000117139 E042 13.2497115 0.0010379456 0.8489731419 0.946429349 1 202742655 202742805 151 - 1.158 1.146 -0.044
ENSG00000117139 E043 0.2458395 0.0163077376 0.9085436512   1 202742806 202743304 499 - 0.101 0.089 -0.204
ENSG00000117139 E044 0.1268540 0.0122833958 0.6232203338   1 202745555 202745857 303 - 0.000 0.089 12.671
ENSG00000117139 E045 13.3815124 0.0226008880 0.9246519923 0.977150746 1 202745858 202745982 125 - 1.150 1.160 0.035
ENSG00000117139 E046 17.8983377 0.0148033192 0.6122423119 0.831266509 1 202746142 202746323 182 - 1.293 1.258 -0.125
ENSG00000117139 E047 0.7426766 0.0140881058 0.5225691311 0.775997894 1 202746324 202747565 1242 - 0.183 0.282 0.796
ENSG00000117139 E048 0.0000000       1 202748397 202748944 548 -      
ENSG00000117139 E049 18.3933046 0.0007452298 0.0053940498 0.052333636 1 202748945 202749139 195 - 1.378 1.193 -0.647
ENSG00000117139 E050 9.4208790 0.0014787849 0.3241757337 0.616679388 1 202750659 202750778 120 - 1.061 0.975 -0.317
ENSG00000117139 E051 9.0332431 0.0031258033 0.1243662696 0.373722442 1 202752905 202753030 126 - 1.071 0.931 -0.518
ENSG00000117139 E052 5.1363050 0.0037426404 0.4373992363 0.713636761 1 202753031 202753067 37 - 0.831 0.745 -0.342
ENSG00000117139 E053 0.5070689 0.1590837188 0.0905954741 0.312635249 1 202754997 202755270 274 - 0.000 0.281 14.191
ENSG00000117139 E054 10.0146520 0.0063353726 0.2051855058 0.488447353 1 202755271 202755452 182 - 1.099 0.985 -0.416
ENSG00000117139 E055 11.2421935 0.0014357696 0.1844257972 0.461572201 1 202756358 202756516 159 - 1.142 1.034 -0.393
ENSG00000117139 E056 0.0000000       1 202758269 202758390 122 -      
ENSG00000117139 E057 6.4651213 0.0024281666 0.1373397146 0.394494961 1 202758391 202758439 49 - 0.949 0.796 -0.588
ENSG00000117139 E058 5.7738480 0.0268127528 0.9394520981 0.982764890 1 202758440 202758510 71 - 0.831 0.826 -0.020
ENSG00000117139 E059 0.2539903 0.0159806888 0.2975028309   1 202758511 202758876 366 - 0.000 0.163 13.596
ENSG00000117139 E060 0.0000000       1 202758877 202759324 448 -      
ENSG00000117139 E061 9.9298758 0.0014155666 0.7407287767 0.897148601 1 202760415 202760529 115 - 1.051 1.024 -0.097
ENSG00000117139 E062 6.8447420 0.0020655063 0.4159791901 0.695995708 1 202760530 202760573 44 - 0.935 0.855 -0.307
ENSG00000117139 E063 8.2954184 0.0016861704 0.1844067275 0.461572201 1 202762699 202762808 110 - 1.030 0.907 -0.460
ENSG00000117139 E064 0.0000000       1 202762809 202762945 137 -      
ENSG00000117139 E065 2.9157608 0.0073623001 0.1176717854 0.362367824 1 202764049 202764073 25 - 0.694 0.485 -0.941
ENSG00000117139 E066 5.8580523 0.0169468363 0.2024042552 0.484810192 1 202764074 202764145 72 - 0.908 0.763 -0.567
ENSG00000117139 E067 3.7495521 0.0039357400 0.0099914238 0.080237858 1 202764146 202766396 2251 - 0.453 0.796 1.512
ENSG00000117139 E068 0.7455743 0.0278439271 0.5256654403 0.778302903 1 202766397 202766504 108 - 0.183 0.282 0.796
ENSG00000117139 E069 0.8614146 0.0149770648 0.8555569240 0.949167023 1 202766505 202766925 421 - 0.252 0.282 0.211
ENSG00000117139 E070 5.8994984 0.0214319402 0.9752284801 0.995551508 1 202766926 202767030 105 - 0.831 0.841 0.037
ENSG00000117139 E071 2.8217938 0.0063360484 0.8830368764 0.960602491 1 202767031 202767051 21 - 0.590 0.572 -0.079
ENSG00000117139 E072 2.1849195 0.0067354028 0.2133021490 0.498520185 1 202767052 202767060 9 - 0.590 0.414 -0.856
ENSG00000117139 E073 0.5076982 0.1578653988 0.0904700391 0.312385255 1 202767061 202767209 149 - 0.000 0.282 14.193
ENSG00000117139 E074 5.3791994 0.0029138491 0.0006031434 0.010108744 1 202770097 202770925 829 - 0.527 0.942 1.713
ENSG00000117139 E075 8.1159069 0.0018818550 0.0001205524 0.002767933 1 202770926 202772694 1769 - 0.694 1.093 1.533
ENSG00000117139 E076 0.6353043 0.0152519096 0.0306832911 0.164778714 1 202772695 202773053 359 - 0.000 0.330 14.778
ENSG00000117139 E077 0.2451451 0.0162445167 0.9082108468   1 202773054 202773117 64 - 0.101 0.089 -0.204
ENSG00000117139 E078 4.3075664 0.0083561815 0.6943775738 0.875226768 1 202773118 202773188 71 - 0.694 0.745 0.211
ENSG00000117139 E079 2.6115578 0.1616062366 0.2606517774 0.553201678 1 202773189 202773216 28 - 0.411 0.645 1.118
ENSG00000117139 E080 4.8258421 0.1162675615 0.3557261195 0.645513570 1 202773217 202773284 68 - 0.670 0.826 0.631
ENSG00000117139 E081 2.6938493 0.0884577875 0.7940823124 0.921488810 1 202773285 202773288 4 - 0.590 0.545 -0.205
ENSG00000117139 E082 2.9407260 0.0110182382 0.7257071326 0.890017247 1 202774613 202774629 17 - 0.618 0.572 -0.204
ENSG00000117139 E083 4.0261622 0.0035635581 0.3490002760 0.639541346 1 202774630 202774735 106 - 0.758 0.645 -0.467
ENSG00000117139 E084 0.1268540 0.0122833958 0.6232203338   1 202776105 202776220 116 - 0.000 0.089 12.671
ENSG00000117139 E085 2.7962617 0.0566121237 0.2211008730 0.508175850 1 202777017 202777094 78 - 0.670 0.485 -0.842
ENSG00000117139 E086 0.4899147 0.1068338950 0.8802397422   1 202777095 202777581 487 - 0.183 0.163 -0.204
ENSG00000117139 E087 0.1268540 0.0122833958 0.6232203338   1 202806490 202806976 487 - 0.000 0.089 12.671
ENSG00000117139 E088 0.1268540 0.0122833958 0.6232203338   1 202806977 202807348 372 - 0.000 0.089 12.671
ENSG00000117139 E089 0.0000000       1 202807963 202808101 139 -      
ENSG00000117139 E090 1.6888892 0.0088318688 0.0603671092 0.246529201 1 202808102 202808116 15 - 0.560 0.282 -1.526
ENSG00000117139 E091 5.0626512 0.0028399516 0.0011082754 0.016220821 1 202808117 202808487 371 - 0.948 0.572 -1.526

Help

Please Click HERE to learn more details about the results from DEXseq.