ENSG00000117226

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370481 ENSG00000117226 No_inf pgKDN_inf GBP3 protein_coding protein_coding 7.207156 8.636304 6.363925 0.9887629 0.2554039 -0.4399015 4.2119687 3.3502740 5.7746151 1.3334869 0.1766252 0.7836421 0.64059167 0.453375 0.909825 0.456450 0.39757766 0.04386525 FALSE TRUE
ENST00000461384 ENSG00000117226 No_inf pgKDN_inf GBP3 protein_coding protein_coding 7.207156 8.636304 6.363925 0.9887629 0.2554039 -0.4399015 0.5089330 0.8419774 0.0000000 0.8419774 0.0000000 -6.4127432 0.05295000 0.074450 0.000000 -0.074450 0.86746319 0.04386525 FALSE TRUE
ENST00000489444 ENSG00000117226 No_inf pgKDN_inf GBP3 protein_coding nonsense_mediated_decay 7.207156 8.636304 6.363925 0.9887629 0.2554039 -0.4399015 0.3052210 0.9156631 0.0000000 0.9156631 0.0000000 -6.5324153 0.02699167 0.080975 0.000000 -0.080975 0.86833717 0.04386525 TRUE TRUE
ENST00000493594 ENSG00000117226 No_inf pgKDN_inf GBP3 protein_coding nonsense_mediated_decay 7.207156 8.636304 6.363925 0.9887629 0.2554039 -0.4399015 0.3156704 0.1587821 0.4520097 0.0918548 0.1825344 1.4527610 0.04766667 0.016600 0.069700 0.053100 0.58963645 0.04386525 FALSE TRUE
MSTRG.1310.4 ENSG00000117226 No_inf pgKDN_inf GBP3 protein_coding   7.207156 8.636304 6.363925 0.9887629 0.2554039 -0.4399015 1.4466293 2.7396987 0.0000000 0.9613057 0.0000000 -8.1031297 0.18167500 0.305500 0.000000 -0.305500 0.04386525 0.04386525 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000117226 E001 0.0000000       1 89006679 89006679 1 -      
ENSG00000117226 E002 0.0000000       1 89006680 89006725 46 -      
ENSG00000117226 E003 21.1943723 0.0008552884 0.181181432 0.45703813 1 89006726 89007269 544 - 1.296 1.378 0.283
ENSG00000117226 E004 20.0327958 0.0007780709 0.995935628 1.00000000 1 89007270 89007768 499 - 1.319 1.321 0.005
ENSG00000117226 E005 6.9678897 0.0080107276 0.009324055 0.07685826 1 89007769 89007852 84 - 0.719 1.002 1.097
ENSG00000117226 E006 0.1268540 0.0124506535 0.630530436   1 89008844 89008934 91 - 0.000 0.089 9.355
ENSG00000117226 E007 0.1268540 0.0124506535 0.630530436   1 89008935 89008946 12 - 0.000 0.089 9.355
ENSG00000117226 E008 11.7482199 0.0013141273 0.062360882 0.25089282 1 89008947 89009140 194 - 1.011 1.164 0.552
ENSG00000117226 E009 7.3454898 0.0024759178 0.529924348 0.78121773 1 89009392 89009494 103 - 0.951 0.892 -0.225
ENSG00000117226 E010 10.9231464 0.0012587658 0.815157697 0.93240404 1 89010904 89011116 213 - 1.083 1.066 -0.063
ENSG00000117226 E011 3.5297934 0.0041896809 0.173454433 0.44671553 1 89011747 89011827 81 - 0.740 0.570 -0.728
ENSG00000117226 E012 5.0629560 0.1580909093 0.593290247 0.82070625 1 89011828 89012027 200 - 0.719 0.823 0.417
ENSG00000117226 E013 0.9886093 0.0167706725 0.630370571 0.84148223 1 89013185 89013197 13 - 0.254 0.329 0.511
ENSG00000117226 E014 7.9514479 0.0029691478 0.303878660 0.59738989 1 89013198 89013427 230 - 1.000 0.904 -0.359
ENSG00000117226 E015 0.2459004 0.0164288363 0.900713967   1 89013428 89014082 655 - 0.102 0.089 -0.225
ENSG00000117226 E016 2.5728042 0.0068430548 0.560919927 0.80139484 1 89014083 89014101 19 - 0.592 0.514 -0.363
ENSG00000117226 E017 6.9283401 0.0226403709 0.035267195 0.17981669 1 89014102 89014279 178 - 1.011 0.777 -0.895
ENSG00000117226 E018 0.3717172 0.2477246416 0.734192680   1 89014405 89014546 142 - 0.102 0.162 0.774
ENSG00000117226 E019 4.5326634 0.0204955394 0.762533165 0.90734818 1 89014547 89014656 110 - 0.761 0.724 -0.148
ENSG00000117226 E020 2.8290339 0.0053529027 0.808213838 0.92917694 1 89015287 89015319 33 - 0.562 0.596 0.153
ENSG00000117226 E021 1.4699946 0.0088574694 0.782060458 0.91618255 1 89015320 89015342 23 - 0.413 0.373 -0.225
ENSG00000117226 E022 3.5516636 0.0056675484 0.537426135 0.78647514 1 89015343 89015414 72 - 0.696 0.620 -0.325
ENSG00000117226 E023 0.2455571 0.0164372562 0.901272350   1 89020126 89020129 4 - 0.102 0.089 -0.225
ENSG00000117226 E024 0.8515642 0.0157084038 0.559700554 0.80063546 1 89020130 89020211 82 - 0.314 0.225 -0.640
ENSG00000117226 E025 0.0000000       1 89020246 89020299 54 -      
ENSG00000117226 E026 0.0000000       1 89020300 89020352 53 -      
ENSG00000117226 E027 0.0000000       1 89020353 89020531 179 -      
ENSG00000117226 E028 7.5936535 0.0020844693 0.520731032 0.77491122 1 89020532 89020743 212 - 0.964 0.904 -0.225
ENSG00000117226 E029 3.1534231 0.0095111456 0.118299545 0.36334668 1 89022684 89022894 211 - 0.719 0.514 -0.903

Help

Please Click HERE to learn more details about the results from DEXseq.