ENSG00000117399

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000310955 ENSG00000117399 No_inf pgKDN_inf CDC20 protein_coding protein_coding 140.7493 121.1459 126.1194 2.138978 0.9610763 0.05803956 92.56209 70.36408 97.61502 1.617876 0.3138835 0.47220678 0.6609833 0.581150 0.774200 0.19305 1.025982e-07 1.025982e-07 FALSE TRUE
ENST00000372462 ENSG00000117399 No_inf pgKDN_inf CDC20 protein_coding protein_coding 140.7493 121.1459 126.1194 2.138978 0.9610763 0.05803956 17.40172 14.88159 14.77388 2.950090 1.0963437 -0.01047291 0.1231417 0.123225 0.117075 -0.00615 1.000000e+00 1.025982e-07 FALSE TRUE
ENST00000482046 ENSG00000117399 No_inf pgKDN_inf CDC20 protein_coding protein_coding_CDS_not_defined 140.7493 121.1459 126.1194 2.138978 0.9610763 0.05803956 28.66095 33.40652 13.73049 2.494097 1.2767848 -1.28212819 0.2017417 0.275000 0.108750 -0.16625 5.279322e-05 1.025982e-07   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000117399 E001 29.916259 0.0034730081 4.350631e-02 0.2035099300 1 43358981 43359006 26 + 1.544 1.428 -0.401
ENSG00000117399 E002 4.524412 0.0031156252 9.392709e-01 0.9826325515 1 43359013 43359166 154 + 0.737 0.748 0.043
ENSG00000117399 E003 109.074125 0.0001579797 3.755892e-01 0.6630812317 1 43359167 43359396 230 + 2.053 2.030 -0.077
ENSG00000117399 E004 82.129260 0.0013675440 6.268080e-01 0.8397193860 1 43359490 43359638 149 + 1.910 1.929 0.065
ENSG00000117399 E005 41.248135 0.0009525930 2.695308e-01 0.5632045214 1 43359725 43359766 42 + 1.650 1.600 -0.170
ENSG00000117399 E006 37.392760 0.0006333059 3.312882e-01 0.6235455227 1 43359767 43359821 55 + 1.559 1.608 0.168
ENSG00000117399 E007 2.031985 0.0266809835 6.594911e-06 0.0002374432 1 43359822 43359968 147 + 0.000 0.706 13.022
ENSG00000117399 E008 92.914994 0.0002711316 3.537131e-01 0.6433684921 1 43359969 43360097 129 + 1.957 1.988 0.102
ENSG00000117399 E009 153.103767 0.0001612741 1.071696e-01 0.3430522566 1 43360193 43360389 197 + 2.205 2.170 -0.119
ENSG00000117399 E010 86.790509 0.0014505808 6.806973e-01 0.8681671485 1 43360499 43360593 95 + 1.950 1.937 -0.042
ENSG00000117399 E011 175.121172 0.0001647782 9.825067e-01 0.9986902635 1 43360733 43360961 229 + 2.245 2.247 0.008
ENSG00000117399 E012 5.850607 0.0289971526 3.532056e-03 0.0389566320 1 43361058 43361119 62 + 0.608 0.986 1.508
ENSG00000117399 E013 136.455563 0.0001224688 9.557344e-01 0.9892827964 1 43361120 43361245 126 + 2.138 2.138 0.002
ENSG00000117399 E014 130.184190 0.0003592471 7.827892e-01 0.9165281411 1 43362195 43362312 118 + 2.121 2.115 -0.017
ENSG00000117399 E015 113.757042 0.0011280073 5.891480e-02 0.2433769972 1 43362951 43363203 253 + 2.030 2.088 0.195

Help

Please Click HERE to learn more details about the results from DEXseq.