ENSG00000117480

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000243167 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding protein_coding 12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 1.4596113 1.4842927 0.7751872 0.12369612 0.4479387 -0.9283542 0.32604167 0.342800 0.124325 -0.218475 0.26645544 0.03457332 FALSE TRUE
ENST00000484697 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding nonsense_mediated_decay 12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.2562568 0.2595242 0.0000000 0.25952416 0.0000000 -4.7523427 0.06152500 0.078550 0.000000 -0.078550 0.83326102 0.03457332 TRUE TRUE
ENST00000489366 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding retained_intron 12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.8748178 1.3367033 0.6409587 0.82829392 0.6409587 -1.0487942 0.16180000 0.227050 0.163600 -0.063450 0.80522321 0.03457332 FALSE TRUE
ENST00000493636 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding retained_intron 12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.1428600 0.0000000 0.4285800 0.00000000 0.4285800 5.4547681 0.04315833 0.000000 0.129475 0.129475 0.95277369 0.03457332 FALSE FALSE
ENST00000493735 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding retained_intron 12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.5041835 0.1855502 0.4491902 0.18555020 0.3061383 1.2315527 0.11791667 0.056175 0.111625 0.055450 0.91171225 0.03457332 TRUE TRUE
MSTRG.935.1 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding   12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 8.1112571 0.0000000 24.3337714 0.00000000 24.3337714 11.2493370 0.08186667 0.000000 0.245600 0.245600 0.55940708 0.03457332   FALSE
MSTRG.935.3 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding   12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.1532118 0.4596353 0.0000000 0.07775592 0.0000000 -5.5534689 0.03467500 0.104025 0.000000 -0.104025 0.03457332 0.03457332 TRUE TRUE
MSTRG.935.6 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding   12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.1589121 0.0000000 0.4767363 0.00000000 0.4767363 5.6050686 0.07512500 0.000000 0.225375 0.225375 0.98752359 0.03457332 TRUE FALSE
MSTRG.935.9 ENSG00000117480 No_inf pgKDN_inf FAAH protein_coding   12.11642 4.545097 27.10442 0.7448291 23.99294 2.573507 0.4553094 0.8193911 0.0000000 0.32459878 0.0000000 -6.3739807 0.09790833 0.191450 0.000000 -0.191450 0.10213477 0.03457332 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000117480 E001 0.1176306 0.012069646 0.26978705   1 46393579 46393631 53 + 0.120 0.000 -11.368
ENSG00000117480 E002 0.0000000       1 46394317 46394328 12 +      
ENSG00000117480 E003 0.0000000       1 46394329 46394370 42 +      
ENSG00000117480 E004 0.1268540 0.012815317 1.00000000   1 46394371 46394543 173 + 0.000 0.075 9.745
ENSG00000117480 E005 0.3623976 0.020021324 0.26651688   1 46402091 46402158 68 + 0.214 0.075 -1.760
ENSG00000117480 E006 0.2457744 0.017408269 0.62061779   1 46402159 46402204 46 + 0.120 0.075 -0.760
ENSG00000117480 E007 0.4994178 0.041225006 0.72537835   1 46405014 46405089 76 + 0.120 0.194 0.825
ENSG00000117480 E008 0.5081680 0.017190086 0.16864290 0.43995291 1 46405090 46405148 59 + 0.000 0.244 11.745
ENSG00000117480 E009 1.3599494 0.015984260 0.92025999 0.97521456 1 46405372 46405505 134 + 0.357 0.365 0.048
ENSG00000117480 E010 0.9870690 0.014461864 0.88439561 0.96108907 1 46405588 46405618 31 + 0.291 0.288 -0.023
ENSG00000117480 E011 2.5583036 0.006138940 0.03252615 0.17086446 1 46405619 46405722 104 + 0.683 0.430 -1.175
ENSG00000117480 E012 1.9599739 0.022669346 0.21536023 0.50111966 1 46405723 46405794 72 + 0.550 0.399 -0.760
ENSG00000117480 E013 0.6092445 0.018529133 0.25248405 0.54400267 1 46405795 46406037 243 + 0.291 0.139 -1.345
ENSG00000117480 E014 0.8633608 0.014510121 0.66013495 0.85812386 1 46406038 46406078 41 + 0.291 0.244 -0.345
ENSG00000117480 E015 1.9659842 0.007749217 0.46095420 0.73200553 1 46406244 46406368 125 + 0.509 0.430 -0.397
ENSG00000117480 E016 2.9638200 0.007496585 0.78126749 0.91582006 1 46408459 46408584 126 + 0.587 0.582 -0.023
ENSG00000117480 E017 0.5077596 0.015516023 0.16833430 0.43953051 1 46408585 46408649 65 + 0.000 0.244 11.745
ENSG00000117480 E018 1.3702089 0.010060524 0.58864809 0.81751375 1 46409101 46409198 98 + 0.291 0.399 0.655
ENSG00000117480 E019 0.7540070 0.015199918 0.33683954 0.62881682 1 46409199 46409380 182 + 0.120 0.288 1.562
ENSG00000117480 E020 0.8779037 0.016325921 0.22800037 0.51646174 1 46410052 46410397 346 + 0.120 0.328 1.825
ENSG00000117480 E021 1.9526759 0.009445681 0.21670634 0.50282713 1 46410398 46410497 100 + 0.550 0.399 -0.760
ENSG00000117480 E022 1.2199106 0.019971643 0.33833297 0.63009843 1 46410814 46410854 41 + 0.414 0.288 -0.760
ENSG00000117480 E023 2.0991375 0.008043671 0.98146588 0.99821571 1 46411612 46411651 40 + 0.464 0.487 0.115
ENSG00000117480 E024 2.6353449 0.007435658 0.02944340 0.16121832 1 46412143 46412251 109 + 0.291 0.642 1.825
ENSG00000117480 E025 1.1423733 0.010734464 0.01251888 0.09292502 1 46413075 46413122 48 + 0.000 0.430 12.915
ENSG00000117480 E026 1.6310596 0.008485119 0.10959017 0.34748007 1 46413123 46413220 98 + 0.214 0.487 1.700
ENSG00000117480 E027 4.3371816 0.194370696 0.91741871 0.97406658 1 46413447 46413848 402 + 0.683 0.726 0.178

Help

Please Click HERE to learn more details about the results from DEXseq.