ENSG00000117758

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373943 ENSG00000117758 No_inf pgKDN_inf STX12 protein_coding protein_coding 43.45085 27.18594 56.73211 1.834188 2.038584 1.061029 35.071746 18.298477 50.8962586 1.398261 1.0496070 1.4753313 0.78465000 0.674375 0.899825 0.225450 0.004273963 0.004273963 FALSE TRUE
ENST00000472285 ENSG00000117758 No_inf pgKDN_inf STX12 protein_coding protein_coding_CDS_not_defined 43.45085 27.18594 56.73211 1.834188 2.038584 1.061029 4.137353 3.667885 2.2031955 1.524374 2.2031955 -0.7327455 0.09967500 0.126825 0.035400 -0.091425 0.271064202 0.004273963   FALSE
MSTRG.534.4 ENSG00000117758 No_inf pgKDN_inf STX12 protein_coding   43.45085 27.18594 56.73211 1.834188 2.038584 1.061029 1.719000 2.957712 0.7006986 1.522626 0.2754224 -2.0620414 0.05490833 0.118675 0.012200 -0.106475 0.224786956 0.004273963 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000117758 E001 1.9312949 0.2662168458 9.691155e-01 0.9936412263 1 27773219 27773234 16 + 0.472 0.392 -0.419
ENSG00000117758 E002 4.1109853 0.0806296399 9.989125e-01 1.0000000000 1 27773235 27773254 20 + 0.692 0.669 -0.096
ENSG00000117758 E003 23.3940369 0.0006250478 4.642891e-01 0.7338442944 1 27773255 27773425 171 + 1.375 1.326 -0.169
ENSG00000117758 E004 16.4829848 0.0032597712 1.944635e-01 0.4743584512 1 27789562 27789631 70 + 1.247 1.141 -0.374
ENSG00000117758 E005 26.6695022 0.0006733480 1.474589e-02 0.1038392382 1 27793533 27793632 100 + 1.459 1.303 -0.540
ENSG00000117758 E006 31.6047288 0.0004406195 1.336134e-02 0.0970279016 1 27801678 27801815 138 + 1.527 1.382 -0.498
ENSG00000117758 E007 1.0989767 0.0767349005 4.240957e-01 0.7032616603 1 27801816 27802039 224 + 0.259 0.392 0.847
ENSG00000117758 E008 2.1002314 0.0649166950 1.121455e-02 0.0867162374 1 27804872 27805148 277 + 0.296 0.702 2.044
ENSG00000117758 E009 2.5465933 0.0079372050 4.817906e-01 0.7467567875 1 27809923 27810245 323 + 0.494 0.595 0.469
ENSG00000117758 E010 10.0870585 0.0015064343 9.880041e-02 0.3280614030 1 27810246 27810246 1 + 1.065 0.902 -0.606
ENSG00000117758 E011 16.6809407 0.0011218631 1.592347e-02 0.1094479074 1 27810247 27810289 43 + 1.274 1.080 -0.692
ENSG00000117758 E012 0.1272623 0.0123152065 2.205383e-01   1 27811992 27812060 69 + 0.000 0.136 9.286
ENSG00000117758 E013 34.8163008 0.0004671855 2.483548e-01 0.5392418245 1 27812163 27812268 106 + 1.546 1.482 -0.216
ENSG00000117758 E014 31.3179708 0.0004639501 2.754363e-01 0.5690016863 1 27817851 27817923 73 + 1.501 1.438 -0.216
ENSG00000117758 E015 1.8417415 0.0074763517 7.291065e-02 0.2743572802 1 27817924 27818074 151 + 0.331 0.595 1.362
ENSG00000117758 E016 32.8326872 0.0208127752 1.613163e-01 0.4293900902 1 27819650 27819732 83 + 1.533 1.426 -0.368
ENSG00000117758 E017 397.5470594 0.0001082688 2.067986e-07 0.0000112321 1 27822231 27824443 2213 + 2.555 2.605 0.168

Help

Please Click HERE to learn more details about the results from DEXseq.