ENSG00000118217

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367942 ENSG00000118217 No_inf pgKDN_inf ATF6 protein_coding protein_coding 37.96585 22.06045 46.43347 0.7652622 0.6717216 1.07336 0.952367 0.000000 2.857101 0.0000000 2.8571009 8.1634489 0.02126667 0.000000 0.063800 0.063800 0.94940129 0.01367646 FALSE TRUE
ENST00000679886 ENSG00000118217 No_inf pgKDN_inf ATF6 protein_coding protein_coding 37.96585 22.06045 46.43347 0.7652622 0.6717216 1.07336 7.419832 7.699715 6.488122 0.7405736 3.7599065 -0.2466545 0.22044167 0.347175 0.136675 -0.210500 0.40228885 0.01367646 FALSE TRUE
ENST00000680688 ENSG00000118217 No_inf pgKDN_inf ATF6 protein_coding protein_coding 37.96585 22.06045 46.43347 0.7652622 0.6717216 1.07336 1.829483 1.483683 1.686965 0.9544296 0.5515957 0.1840835 0.05166667 0.066325 0.036600 -0.029725 0.97232478 0.01367646 FALSE TRUE
ENST00000681187 ENSG00000118217 No_inf pgKDN_inf ATF6 protein_coding protein_coding_CDS_not_defined 37.96585 22.06045 46.43347 0.7652622 0.6717216 1.07336 1.978097 1.372860 2.741445 0.4663590 0.2790516 0.9925341 0.05315833 0.060500 0.058875 -0.001625 0.99435148 0.01367646 FALSE TRUE
ENST00000681801 ENSG00000118217 No_inf pgKDN_inf ATF6 protein_coding nonsense_mediated_decay 37.96585 22.06045 46.43347 0.7652622 0.6717216 1.07336 22.445192 8.603558 28.156595 0.8468722 0.5859968 1.7093040 0.55557500 0.387550 0.606375 0.218825 0.01367646 0.01367646 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000118217 E001 0.1187032 1.186185e-02 9.015574e-01   1 161766298 161766308 11 + 0.077 0.000 -10.546
ENSG00000118217 E002 0.1187032 1.186185e-02 9.015574e-01   1 161766309 161766310 2 + 0.077 0.000 -12.575
ENSG00000118217 E003 0.2363338 1.570801e-02 4.510940e-01   1 161766311 161766319 9 + 0.143 0.000 -13.508
ENSG00000118217 E004 0.2363338 1.570801e-02 4.510940e-01   1 161766320 161766320 1 + 0.143 0.000 -13.508
ENSG00000118217 E005 0.2363338 1.570801e-02 4.510940e-01   1 161766321 161766321 1 + 0.143 0.000 -13.508
ENSG00000118217 E006 1.1989469 1.031842e-02 2.135393e-01 4.987385e-01 1 161766322 161766341 20 + 0.407 0.209 -1.334
ENSG00000118217 E007 2.6418173 5.512034e-03 1.197442e-01 3.657219e-01 1 161766342 161766355 14 + 0.634 0.405 -1.099
ENSG00000118217 E008 13.0195763 2.630750e-03 3.822120e-02 1.887567e-01 1 161766356 161766442 87 + 1.203 1.024 -0.646
ENSG00000118217 E009 0.1187032 1.186185e-02 9.015574e-01   1 161766515 161766563 49 + 0.077 0.000 -12.575
ENSG00000118217 E010 0.1187032 1.186185e-02 9.015574e-01   1 161766564 161766575 12 + 0.077 0.000 -12.575
ENSG00000118217 E011 0.3642603 1.964176e-01 1.000000e+00   1 161766576 161766806 231 + 0.143 0.117 -0.335
ENSG00000118217 E012 17.2501186 1.876812e-02 1.024363e-01 3.346132e-01 1 161778244 161778316 73 + 1.310 1.154 -0.551
ENSG00000118217 E013 8.9289199 8.824555e-03 2.178786e-01 5.042908e-01 1 161778317 161778320 4 + 1.038 0.908 -0.482
ENSG00000118217 E014 0.1186381 1.184825e-02 9.015558e-01   1 161778670 161778695 26 + 0.077 0.000 -12.575
ENSG00000118217 E015 20.6348415 2.301102e-03 2.227490e-02 1.357250e-01 1 161781912 161781999 88 + 1.386 1.223 -0.568
ENSG00000118217 E016 21.7373582 1.284979e-02 3.963501e-02 1.930066e-01 1 161783990 161784096 107 + 1.410 1.239 -0.595
ENSG00000118217 E017 22.4942246 5.085966e-03 1.044063e-01 3.377145e-01 1 161791408 161791537 130 + 1.406 1.290 -0.404
ENSG00000118217 E018 32.5048395 2.508066e-03 3.582786e-02 1.815938e-01 1 161792124 161792327 204 + 1.563 1.440 -0.423
ENSG00000118217 E019 33.4083831 7.058252e-04 7.830962e-02 2.864990e-01 1 161802052 161802272 221 + 1.565 1.468 -0.334
ENSG00000118217 E020 42.8494225 3.454676e-04 7.622934e-01 9.072585e-01 1 161819633 161819818 186 + 1.641 1.623 -0.060
ENSG00000118217 E021 31.9233302 4.328018e-04 4.589297e-02 2.098941e-01 1 161821070 161821161 92 + 1.551 1.440 -0.383
ENSG00000118217 E022 0.2374063 2.526759e-01 5.131264e-01   1 161840075 161840468 394 + 0.143 0.000 -12.775
ENSG00000118217 E023 38.7633740 4.679820e-04 1.931285e-03 2.490125e-02 1 161846449 161846580 132 + 1.649 1.490 -0.541
ENSG00000118217 E024 1.2160043 9.820204e-03 9.208415e-01 9.752465e-01 1 161851665 161851721 57 + 0.336 0.349 0.081
ENSG00000118217 E025 33.8163008 4.516818e-04 4.347735e-01 7.118575e-01 1 161851722 161851835 114 + 1.551 1.507 -0.151
ENSG00000118217 E026 30.9903229 6.513239e-03 2.032653e-01 4.857724e-01 1 161853224 161853323 100 + 1.529 1.444 -0.292
ENSG00000118217 E027 21.4056692 9.434620e-03 2.313969e-01 5.199634e-01 1 161860207 161860277 71 + 1.379 1.283 -0.334
ENSG00000118217 E028 10.4195983 1.206700e-02 6.881057e-01 8.715079e-01 1 161863198 161863200 3 + 1.068 1.024 -0.161
ENSG00000118217 E029 30.2241853 7.678786e-03 9.264907e-01 9.779882e-01 1 161863201 161863312 112 + 1.490 1.481 -0.031
ENSG00000118217 E030 1.0883977 1.104462e-02 7.520887e-01 9.024157e-01 1 161863313 161864740 1428 + 0.336 0.284 -0.334
ENSG00000118217 E031 3.6371668 3.722820e-02 8.456235e-01 9.450825e-01 1 161864741 161865955 1215 + 0.671 0.643 -0.123
ENSG00000118217 E032 0.2536433 1.601257e-02 1.188519e-01   1 161870972 161871061 90 + 0.000 0.209 13.347
ENSG00000118217 E033 15.0913831 1.001518e-03 4.303659e-01 7.083153e-01 1 161887262 161888547 1286 + 1.176 1.231 0.197
ENSG00000118217 E034 29.4311329 1.256684e-02 4.514713e-01 7.245503e-01 1 161912296 161912380 85 + 1.498 1.440 -0.202
ENSG00000118217 E035 0.2458395 1.650335e-02 7.146578e-01   1 161936378 161936523 146 + 0.077 0.117 0.666
ENSG00000118217 E036 74.7670964 4.970702e-04 1.566548e-02 1.082588e-01 1 161958446 161958710 265 + 1.906 1.816 -0.302
ENSG00000118217 E037 335.6330604 9.505448e-05 3.404396e-26 1.542964e-23 1 161958711 161964070 5360 + 2.458 2.595 0.456
ENSG00000118217 E038 0.1271363 1.233240e-02 3.292851e-01   1 161975186 161975373 188 + 0.000 0.117 12.405
ENSG00000118217 E039 0.0000000       1 161975926 161977574 1649 +      

Help

Please Click HERE to learn more details about the results from DEXseq.