ENSG00000118308

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354454 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding protein_coding 55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 5.604323 11.9497363 1.271687 1.9978463 0.7345187 -3.222070 0.12548333 0.106125 0.053125 -0.053000 0.55343784 0.01270732 FALSE  
ENST00000555194 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding retained_intron 55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 8.916981 23.1349029 2.987948 5.0300728 2.4462519 -2.948647 0.11748333 0.202525 0.108375 -0.094150 0.45805200 0.01270732    
ENST00000556887 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding protein_coding 55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 6.960438 12.7012978 5.796520 2.8487923 2.0089885 -1.130366 0.16090833 0.110750 0.222200 0.111450 0.84622101 0.01270732 FALSE  
MSTRG.6186.2 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding   55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 1.442378 0.9785661 3.348566 0.9785661 3.3485665 1.764436 0.03359167 0.008600 0.092175 0.083575 0.84244436 0.01270732    
MSTRG.6186.22 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding   55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 4.704652 7.0756782 5.717204 4.4591767 2.3363785 -0.307075 0.11059167 0.067250 0.194325 0.127075 0.66116105 0.01270732 FALSE  
MSTRG.6186.24 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding   55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 5.817828 12.8723348 1.527364 5.6180428 1.5273636 -3.066864 0.11360000 0.097475 0.076300 -0.021175 0.27224717 0.01270732 FALSE  
MSTRG.6186.28 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding   55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 3.471254 8.6703613 0.132660 2.0940904 0.1326600 -5.927102 0.05840833 0.080275 0.005025 -0.075250 0.01270732 0.01270732 TRUE  
MSTRG.6186.4 ENSG00000118308 No_inf pgKDN_inf IRAG2 protein_coding   55.26253 120.0858 28.05885 16.98733 3.385149 -2.097143 6.025862 18.0775869 0.000000 18.0775869 0.0000000 -10.820784 0.03560000 0.106800 0.000000 -0.106800 1.00000000 0.01270732    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000118308 E001 0.7531559 0.0334375615 1.000000000 1.00000000 12 25004342 25004915 574 + 0.178 0.202 0.225
ENSG00000118308 E002 0.1271363 0.0124039993 1.000000000   12 25005241 25005243 3 + 0.000 0.049 11.812
ENSG00000118308 E003 0.7280127 0.4092510604 0.052786975 0.22834558 12 25005244 25005354 111 + 0.481 0.092 -3.099
ENSG00000118308 E004 0.1176306 0.0118934913 0.089514418   12 25011344 25011370 27 + 0.178 0.000 -15.274
ENSG00000118308 E005 0.6179948 0.0216807412 0.271851673 0.56562179 12 25011371 25011551 181 + 0.304 0.132 -1.513
ENSG00000118308 E006 0.3721553 0.2327120084 0.488859373   12 25015182 25015261 80 + 0.178 0.092 -1.097
ENSG00000118308 E007 0.7424589 0.1381433197 0.416392517 0.69625528 12 25015350 25015428 79 + 0.304 0.168 -1.097
ENSG00000118308 E008 0.6162040 0.3594067040 0.288623192 0.58217771 12 25017134 25017292 159 + 0.304 0.132 -1.512
ENSG00000118308 E009 0.2438580 0.0163809455 0.251687728   12 25020790 25020907 118 + 0.178 0.049 -2.097
ENSG00000118308 E010 0.0000000       12 25021002 25021045 44 +      
ENSG00000118308 E011 0.1268540 0.0124045769 1.000000000   12 25023871 25023921 51 + 0.000 0.049 11.812
ENSG00000118308 E012 0.0000000       12 25026789 25026863 75 +      
ENSG00000118308 E013 0.1272623 0.0124126392 1.000000000   12 25026864 25026866 3 + 0.000 0.049 11.812
ENSG00000118308 E014 0.1272623 0.0124126392 1.000000000   12 25026867 25026887 21 + 0.000 0.049 11.812
ENSG00000118308 E015 0.2545247 0.2731481005 1.000000000   12 25030278 25030334 57 + 0.000 0.092 12.352
ENSG00000118308 E016 0.1272623 0.0124126392 1.000000000   12 25032142 25032201 60 + 0.000 0.049 11.812
ENSG00000118308 E017 0.3717172 0.2228848830 0.489366368   12 25032305 25032369 65 + 0.178 0.092 -1.098
ENSG00000118308 E018 0.1186381 0.0118410068 0.089561997   12 25033759 25033847 89 + 0.178 0.000 -15.275
ENSG00000118308 E019 1.1250340 0.0157146194 0.800322105 0.92527940 12 25033848 25033947 100 + 0.304 0.262 -0.290
ENSG00000118308 E020 0.0000000       12 25035480 25035652 173 +      
ENSG00000118308 E021 0.6270921 0.0150511013 1.000000000 1.00000000 12 25035653 25035787 135 + 0.178 0.168 -0.097
ENSG00000118308 E022 0.5085453 0.7285228066 1.000000000 1.00000000 12 25036585 25036631 47 + 0.000 0.168 13.041
ENSG00000118308 E023 1.0156756 0.0145315196 0.175729811 0.44987079 12 25036632 25036686 55 + 0.000 0.289 14.548
ENSG00000118308 E024 0.6341407 0.0150826807 0.427610709 0.70619009 12 25037974 25038137 164 + 0.000 0.202 13.957
ENSG00000118308 E025 0.2537079 0.3020943992 1.000000000   12 25052235 25052254 20 + 0.000 0.092 12.326
ENSG00000118308 E026 0.1272623 0.0124126392 1.000000000   12 25052255 25052270 16 + 0.000 0.049 11.812
ENSG00000118308 E027 0.1272623 0.0124126392 1.000000000   12 25052271 25052271 1 + 0.000 0.049 11.812
ENSG00000118308 E028 0.3813786 0.0309297152 1.000000000   12 25052272 25052297 26 + 0.000 0.132 13.252
ENSG00000118308 E029 1.7513964 0.0080403826 0.808880848 0.92942286 12 25052298 25052349 52 + 0.401 0.362 -0.223
ENSG00000118308 E030 1.9905009 0.0084733914 0.239661969 0.52871109 12 25052350 25052511 162 + 0.548 0.362 -0.960
ENSG00000118308 E031 1.9970499 0.0103587057 0.547986438 0.79325960 12 25052512 25052586 75 + 0.481 0.384 -0.513
ENSG00000118308 E032 3.2822936 0.0048654705 0.109579663 0.34746720 12 25052587 25052641 55 + 0.304 0.584 1.487
ENSG00000118308 E033 4.8152991 0.0029789316 0.002147058 0.02693943 12 25052642 25052699 58 + 0.178 0.731 3.112
ENSG00000118308 E034 2.9117437 0.0049413787 0.040178991 0.19428311 12 25052700 25052705 6 + 0.178 0.557 2.362
ENSG00000118308 E035 4.6667584 0.0052668561 0.068536108 0.26425697 12 25052706 25052739 34 + 0.401 0.701 1.405
ENSG00000118308 E036 7.3042447 0.0157477680 0.093701209 0.31831291 12 25052740 25052765 26 + 0.606 0.854 1.018
ENSG00000118308 E037 8.8931359 0.0062163066 0.910829070 0.97178566 12 25052766 25052793 28 + 0.880 0.896 0.060
ENSG00000118308 E038 29.4027989 0.0005525031 0.534013748 0.78430106 12 25052794 25052944 151 + 1.403 1.364 -0.136
ENSG00000118308 E039 14.1004732 0.0009895576 0.182462208 0.45884817 12 25052945 25052956 12 + 1.166 1.048 -0.426
ENSG00000118308 E040 7.7506348 0.0017979326 0.673389734 0.86476612 12 25061592 25061653 62 + 0.880 0.832 -0.183
ENSG00000118308 E041 18.2431792 0.0009463052 0.349783265 0.64005674 12 25062820 25062900 81 + 1.236 1.161 -0.265
ENSG00000118308 E042 8.6752811 0.0262078426 0.014595330 0.10314263 12 25063720 25063722 3 + 1.102 0.817 -1.066
ENSG00000118308 E043 25.7155606 0.0005954365 0.108108634 0.34478925 12 25063723 25063816 94 + 1.403 1.294 -0.379
ENSG00000118308 E044 33.0982651 0.0006715329 0.551095489 0.79503117 12 25066365 25066512 148 + 1.385 1.428 0.147
ENSG00000118308 E045 1.0064871 0.0321671945 0.670387281 0.86303891 12 25068183 25068248 66 + 0.178 0.262 0.710
ENSG00000118308 E046 24.0571057 0.0005897686 0.827851705 0.93771968 12 25069350 25069431 82 + 1.272 1.292 0.068
ENSG00000118308 E047 0.2536433 0.0160666713 1.000000000   12 25075740 25075802 63 + 0.000 0.092 12.749
ENSG00000118308 E048 0.7522443 0.0130421596 1.000000000 1.00000000 12 25076584 25076640 57 + 0.178 0.202 0.224
ENSG00000118308 E049 24.6373695 0.0005677891 0.481174582 0.74633814 12 25079244 25079290 47 + 1.338 1.289 -0.170
ENSG00000118308 E050 30.8879837 0.0004523918 0.374948401 0.66259722 12 25079398 25079462 65 + 1.437 1.382 -0.191
ENSG00000118308 E051 2.0021799 0.0069022139 0.992257488 1.00000000 12 25079463 25079655 193 + 0.401 0.405 0.018
ENSG00000118308 E052 23.7794028 0.0006480440 0.007593143 0.06666589 12 25079656 25079701 46 + 1.429 1.245 -0.641
ENSG00000118308 E053 23.3435103 0.0025897428 0.167608159 0.43829229 12 25079702 25079763 62 + 1.357 1.256 -0.354
ENSG00000118308 E054 23.2768777 0.0017168906 0.717037886 0.88607450 12 25083423 25083493 71 + 1.295 1.270 -0.088
ENSG00000118308 E055 23.4262707 0.0016713478 0.819091895 0.93413056 12 25088100 25088157 58 + 1.260 1.281 0.072
ENSG00000118308 E056 21.9545601 0.0193429281 0.509387909 0.76728279 12 25089614 25089677 64 + 1.195 1.262 0.235
ENSG00000118308 E057 12.5328939 0.0019719442 0.829263578 0.93823163 12 25089763 25089773 11 + 1.005 1.029 0.090
ENSG00000118308 E058 11.7610128 0.0012306642 0.736675249 0.89557304 12 25089774 25089790 17 + 1.026 0.994 -0.117
ENSG00000118308 E059 26.2158790 0.0238040343 0.556296902 0.79862481 12 25090057 25090197 141 + 1.272 1.334 0.217
ENSG00000118308 E060 0.8703208 0.0124963560 0.534578121 0.78456884 12 25090816 25091120 305 + 0.304 0.202 -0.776
ENSG00000118308 E061 0.0000000       12 25096910 25096932 23 +      
ENSG00000118308 E062 0.0000000       12 25096933 25096957 25 +      
ENSG00000118308 E063 0.0000000       12 25096958 25097044 87 +      
ENSG00000118308 E064 0.5078857 0.0158778929 0.609490462 0.83014947 12 25101142 25101177 36 + 0.000 0.168 13.668
ENSG00000118308 E065 33.9403730 0.0004297660 0.868184408 0.95480634 12 25101178 25101325 148 + 1.420 1.434 0.047
ENSG00000118308 E066 0.1271363 0.0124039993 1.000000000   12 25101938 25102025 88 + 0.000 0.049 11.812
ENSG00000118308 E067 14.0251015 0.0068989959 0.983999497 0.99872088 12 25102198 25102241 44 + 1.066 1.071 0.018
ENSG00000118308 E068 4.5619987 0.0052684633 0.003320590 0.03729472 12 25102242 25102778 537 + 0.178 0.711 3.032
ENSG00000118308 E069 10.2726910 0.0012974007 0.899114172 0.96697489 12 25103837 25103899 63 + 0.934 0.951 0.062
ENSG00000118308 E070 37.3318040 0.0003861684 0.983708202 0.99869026 12 25104009 25104058 50 + 1.468 1.472 0.014
ENSG00000118308 E071 3.4002400 0.0042068502 0.276917274 0.57035272 12 25104329 25104360 32 + 0.401 0.584 0.903
ENSG00000118308 E072 69.3873700 0.0002395930 0.853489761 0.94832158 12 25104361 25104462 102 + 1.738 1.732 -0.018
ENSG00000118308 E073 4.5406287 0.0032239734 0.077915961 0.28556126 12 25104738 25104829 92 + 0.401 0.691 1.362
ENSG00000118308 E074 59.2402620 0.0002684542 0.818298989 0.93391747 12 25106943 25107050 108 + 1.673 1.665 -0.028
ENSG00000118308 E075 139.4311871 0.0001412237 0.016613872 0.11231544 12 25107817 25108335 519 + 1.967 2.045 0.264

Help

Please Click HERE to learn more details about the results from DEXseq.