ENSG00000118420

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000237186 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding nonsense_mediated_decay 2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.46234100 0.97751595 0.40950704 0.56491767 0.40950704 -1.2351090 0.19208333 0.468375 0.107875 -0.360500 0.83916779 0.04528063 FALSE TRUE
ENST00000369746 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding nonsense_mediated_decay 2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.07819431 0.02224749 0.21233543 0.02224749 0.08767986 2.7854793 0.03111667 0.006400 0.086950 0.080550 0.44010486 0.04528063 TRUE TRUE
ENST00000369747 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding protein_coding 2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.81713117 0.00000000 1.14433655 0.00000000 0.40816686 6.8509201 0.42087500 0.000000 0.660100 0.660100 0.04528063 0.04528063 FALSE TRUE
ENST00000503942 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding protein_coding_CDS_not_defined 2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.31719756 0.54725500 0.40433768 0.54725500 0.40433768 -0.4275306 0.08804167 0.157600 0.106525 -0.051075 0.98200123 0.04528063   FALSE
ENST00000505226 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding nonsense_mediated_decay 2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.15733930 0.20007021 0.07445239 0.09150679 0.02942956 -1.3146614 0.06117500 0.069225 0.038550 -0.030675 0.82243267 0.04528063 FALSE TRUE
ENST00000509102 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding nonsense_mediated_decay 2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.18530142 0.18089659 0.00000000 0.18089659 0.00000000 -4.2547194 0.06345000 0.052100 0.000000 -0.052100 0.85935918 0.04528063 TRUE TRUE
MSTRG.24958.4 ENSG00000118420 No_inf pgKDN_inf UBE3D protein_coding   2.691694 3.02032 2.244969 0.5741544 0.5385121 -0.4263626 0.49305597 0.71892925 0.00000000 0.71892925 0.00000000 -6.1877069 0.10401667 0.162100 0.000000 -0.162100 0.86950590 0.04528063   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000118420 E001 0.0000000       6 82892390 82892397 8 -      
ENSG00000118420 E002 0.0000000       6 82892398 82892466 69 -      
ENSG00000118420 E003 1.2306472 0.020699677 0.433321817 0.71082125 6 82892467 82892669 203 - 0.288 0.402 0.693
ENSG00000118420 E004 4.3069314 0.003838984 0.227677078 0.51611717 6 82892670 82892952 283 - 0.657 0.784 0.523
ENSG00000118420 E005 2.4502672 0.006189366 0.833318970 0.93992148 6 82892953 82893024 72 - 0.526 0.549 0.108
ENSG00000118420 E006 1.0804375 0.011987737 0.110251563 0.34839735 6 82893025 82893042 18 - 0.423 0.178 -1.699
ENSG00000118420 E007 0.0000000       6 82893964 82894033 70 -      
ENSG00000118420 E008 0.0000000       6 82912882 82912942 61 -      
ENSG00000118420 E009 0.0000000       6 82933135 82933192 58 -      
ENSG00000118420 E010 2.3022270 0.007592625 0.328614163 0.62110828 6 82957312 82957450 139 - 0.583 0.444 -0.669
ENSG00000118420 E011 1.1854840 0.015208130 0.009939983 0.07994687 6 83017182 83018972 1791 - 0.494 0.098 -3.062
ENSG00000118420 E012 2.3569585 0.008380260 0.060184721 0.24622641 6 83018973 83019136 164 - 0.383 0.634 1.224
ENSG00000118420 E013 0.6164842 0.018120223 0.580361336 0.81277583 6 83022453 83022478 26 - 0.168 0.246 0.693
ENSG00000118420 E014 0.7440934 0.013900732 0.347505336 0.63814616 6 83022479 83022561 83 - 0.168 0.305 1.108
ENSG00000118420 E015 1.1985037 0.011755351 0.066061609 0.25882368 6 83023969 83024038 70 - 0.460 0.178 -1.892
ENSG00000118420 E016 0.0000000       6 83032242 83032310 69 -      
ENSG00000118420 E017 1.7411693 0.012867400 0.068019641 0.26320989 6 83036026 83038415 2390 - 0.288 0.549 1.430
ENSG00000118420 E018 0.9506831 0.013237548 0.033799244 0.17497873 6 83038416 83038485 70 - 0.423 0.098 -2.699
ENSG00000118420 E019 1.6961961 0.008079096 0.355961802 0.64573990 6 83044428 83044659 232 - 0.494 0.356 -0.740
ENSG00000118420 E020 0.0000000       6 83049709 83049772 64 -      
ENSG00000118420 E021 0.7440961 0.015074291 0.349225405 0.63959930 6 83054148 83054238 91 - 0.168 0.305 1.108
ENSG00000118420 E022 2.0692328 0.006786448 0.578261841 0.81153168 6 83057826 83058022 197 - 0.526 0.444 -0.406
ENSG00000118420 E023 0.0000000       6 83063153 83063208 56 -      
ENSG00000118420 E024 0.0000000       6 83063209 83063245 37 -      
ENSG00000118420 E025 0.7355952 0.014501241 0.910441418 0.97165877 6 83065642 83065679 38 - 0.232 0.246 0.108
ENSG00000118420 E026 0.9896469 0.013375762 0.398495381 0.68236057 6 83065680 83065841 162 - 0.232 0.356 0.845

Help

Please Click HERE to learn more details about the results from DEXseq.