ENSG00000118515

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000237305 ENSG00000118515 No_inf pgKDN_inf SGK1 protein_coding protein_coding 270.2298 51.01844 340.8107 6.461755 8.224259 2.739639 195.46893 22.725025 259.94322 1.3776843 5.006034 3.5152635 0.64999167 0.459100 0.764925 0.305825 8.014420e-07 8.01442e-07 FALSE TRUE
ENST00000367855 ENSG00000118515 No_inf pgKDN_inf SGK1 protein_coding retained_intron 270.2298 51.01844 340.8107 6.461755 8.224259 2.739639 13.64439 6.947594 12.21584 1.5204219 1.062099 0.8132738 0.07777500 0.145275 0.035850 -0.109425 1.556871e-02 8.01442e-07 TRUE TRUE
ENST00000477460 ENSG00000118515 No_inf pgKDN_inf SGK1 protein_coding retained_intron 270.2298 51.01844 340.8107 6.461755 8.224259 2.739639 20.08672 5.797073 23.26785 2.4283813 7.919168 2.0030747 0.08479167 0.111425 0.067875 -0.043550 9.602472e-01 8.01442e-07 FALSE TRUE
MSTRG.25327.29 ENSG00000118515 No_inf pgKDN_inf SGK1 protein_coding   270.2298 51.01844 340.8107 6.461755 8.224259 2.739639 10.71039 6.469770 14.56875 6.4697700 8.411405 1.1698526 0.05298333 0.092325 0.041650 -0.050675 9.701953e-01 8.01442e-07   FALSE
MSTRG.25327.6 ENSG00000118515 No_inf pgKDN_inf SGK1 protein_coding   270.2298 51.01844 340.8107 6.461755 8.224259 2.739639 11.54250 4.302617 14.08866 0.9843877 2.568224 1.7089230 0.05776667 0.093700 0.040875 -0.052825 5.283347e-01 8.01442e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000118515 E001 0.2352613 2.887019e-01 1.000000e+00   6 134169248 134169249 2 - 0.075 0.000 -8.402
ENSG00000118515 E002 0.5885991 4.108158e-02 9.322312e-01 0.9802841818 6 134169250 134169251 2 - 0.168 0.000 -12.032
ENSG00000118515 E003 1.3057201 9.590668e-03 7.301303e-01 0.8926003523 6 134169252 134169255 4 - 0.288 0.214 -0.569
ENSG00000118515 E004 4.2790349 6.655881e-03 3.874184e-01 0.6733126663 6 134169256 134169283 28 - 0.614 0.463 -0.707
ENSG00000118515 E005 44.9167889 3.089739e-04 9.012038e-01 0.9681025354 6 134169284 134169352 69 - 1.505 1.498 -0.024
ENSG00000118515 E006 635.2903883 4.815634e-05 3.686549e-01 0.6571249695 6 134169353 134169880 528 - 2.640 2.655 0.051
ENSG00000118515 E007 315.1103116 9.932826e-05 3.452481e-01 0.6362758468 6 134169881 134170105 225 - 2.342 2.320 -0.073
ENSG00000118515 E008 372.4784824 8.374749e-04 7.009307e-01 0.8781823570 6 134170106 134170435 330 - 2.410 2.420 0.034
ENSG00000118515 E009 28.0688305 1.627699e-02 6.259557e-04 0.0103750145 6 134170436 134170799 364 - 1.254 1.548 1.016
ENSG00000118515 E010 4.9648831 3.549884e-03 5.791600e-04 0.0097919798 6 134170800 134170825 26 - 0.550 0.995 1.805
ENSG00000118515 E011 110.5841155 1.585114e-04 2.593401e-01 0.5518740161 6 134170826 134170915 90 - 1.894 1.847 -0.158
ENSG00000118515 E012 10.3798971 1.298387e-03 3.145990e-05 0.0008977558 6 134170916 134171022 107 - 0.823 1.244 1.546
ENSG00000118515 E013 122.1193413 1.363365e-04 1.064000e-01 0.3415616606 6 134171023 134171104 82 - 1.938 1.873 -0.219
ENSG00000118515 E014 129.0672441 1.248373e-04 3.377024e-01 0.6295070417 6 134171105 134171178 74 - 1.959 1.922 -0.123
ENSG00000118515 E015 8.8510980 2.186088e-02 1.819542e-01 0.4579765756 6 134171179 134171364 186 - 0.823 0.995 0.654
ENSG00000118515 E016 8.9804772 1.054836e-02 1.029119e-01 0.3353747723 6 134171365 134171636 272 - 0.823 1.023 0.753
ENSG00000118515 E017 59.9911504 2.501054e-04 3.020022e-01 0.5952057955 6 134171637 134171650 14 - 1.618 1.676 0.195
ENSG00000118515 E018 98.4553395 1.779640e-04 6.307667e-02 0.2526533450 6 134171651 134171732 82 - 1.826 1.905 0.268
ENSG00000118515 E019 14.8304264 4.122765e-03 2.818222e-05 0.0008229453 6 134171733 134172192 460 - 0.973 1.354 1.365
ENSG00000118515 E020 131.4347386 1.309213e-04 2.677615e-01 0.5612033903 6 134172193 134172316 124 - 1.956 1.998 0.142
ENSG00000118515 E021 5.6033591 1.237749e-02 9.772672e-01 0.9965198716 6 134172317 134172599 283 - 0.687 0.682 -0.020
ENSG00000118515 E022 2.5367694 9.354408e-03 6.236269e-02 0.2508928158 6 134172600 134172661 62 - 0.383 0.682 1.431
ENSG00000118515 E023 85.6310498 4.392390e-03 6.958533e-01 0.8759128351 6 134172662 134172723 62 - 1.781 1.760 -0.071
ENSG00000118515 E024 46.0413032 6.310074e-03 4.069182e-01 0.6894982246 6 134172724 134172725 2 - 1.523 1.462 -0.210
ENSG00000118515 E025 76.5379740 8.554636e-04 3.958945e-01 0.6807860331 6 134172726 134172774 49 - 1.736 1.693 -0.146
ENSG00000118515 E026 2.7406040 7.493500e-03 9.881390e-01 0.9999304082 6 134172775 134172776 2 - 0.460 0.463 0.016
ENSG00000118515 E027 9.5631604 1.473455e-02 2.719584e-01 0.5657565254 6 134172777 134173022 246 - 0.859 0.995 0.516
ENSG00000118515 E028 67.3945465 2.187967e-04 4.240521e-01 0.7032475478 6 134173023 134173063 41 - 1.682 1.639 -0.144
ENSG00000118515 E029 58.0432645 2.698266e-04 9.002133e-02 0.3116416899 6 134173064 134173080 17 - 1.625 1.524 -0.346
ENSG00000118515 E030 62.4126028 2.445386e-04 2.139121e-02 0.1324679684 6 134173081 134173116 36 - 1.660 1.524 -0.463
ENSG00000118515 E031 72.3903177 2.071036e-04 1.769919e-02 0.1170268544 6 134173117 134173154 38 - 1.722 1.593 -0.441
ENSG00000118515 E032 1.5460838 4.378581e-02 5.861819e-01 0.8164433607 6 134173155 134173171 17 - 0.329 0.214 -0.833
ENSG00000118515 E033 2.7623745 8.701837e-03 2.514320e-01 0.5425811709 6 134173172 134173273 102 - 0.431 0.621 0.905
ENSG00000118515 E034 90.3340909 1.916305e-04 3.066344e-01 0.5998243530 6 134173274 134173357 84 - 1.807 1.760 -0.159
ENSG00000118515 E035 1.0709865 1.753260e-01 1.000000e+00 1.0000000000 6 134173358 134173461 104 - 0.244 0.214 -0.247
ENSG00000118515 E036 105.0795888 1.478557e-04 9.041814e-01 0.9691585463 6 134173462 134173554 93 - 1.866 1.862 -0.014
ENSG00000118515 E037 53.8862940 2.563913e-04 7.291813e-01 0.8920063150 6 134173555 134173566 12 - 1.578 1.599 0.073
ENSG00000118515 E038 0.9416910 1.510912e-02 3.885425e-01 0.6743449895 6 134173567 134173699 133 - 0.244 0.000 -12.982
ENSG00000118515 E039 1.7782381 1.123908e-01 5.072576e-01 0.7657476493 6 134173700 134173800 101 - 0.365 0.214 -1.054
ENSG00000118515 E040 1.4177569 4.735564e-02 1.891756e-01 0.4677490892 6 134173801 134173908 108 - 0.329 0.000 -13.203
ENSG00000118515 E041 0.7254656 1.396607e-02 1.951130e-01 0.4753895793 6 134173909 134174004 96 - 0.139 0.356 1.753
ENSG00000118515 E042 93.6409818 1.708811e-04 9.793712e-01 0.9975336839 6 134174005 134174080 76 - 1.816 1.818 0.008
ENSG00000118515 E043 3.2011130 4.466808e-03 3.589515e-01 0.6484789371 6 134174081 134174305 225 - 0.526 0.356 -0.891
ENSG00000118515 E044 1.7849044 2.510331e-02 9.641934e-01 0.9924389421 6 134174306 134174510 205 - 0.347 0.356 0.053
ENSG00000118515 E045 88.5610572 2.061793e-04 4.163223e-01 0.6961810574 6 134174511 134174586 76 - 1.798 1.760 -0.127
ENSG00000118515 E046 0.6160409 2.203141e-01 2.533153e-02 0.1464969809 6 134174587 134174731 145 - 0.075 0.463 3.338
ENSG00000118515 E047 83.3649331 2.296213e-04 5.210457e-01 0.7751870173 6 134174732 134174896 165 - 1.771 1.740 -0.102
ENSG00000118515 E048 3.6080834 1.351253e-02 1.305254e-01 0.3832729651 6 134175544 134175991 448 - 0.501 0.736 1.036
ENSG00000118515 E049 3.0808433 6.424029e-03 1.162898e-01 0.3595348018 6 134177663 134177905 243 - 0.526 0.214 -1.891
ENSG00000118515 E050 0.5934507 3.504269e-01 1.000000e+00 1.0000000000 6 134180255 134180343 89 - 0.168 0.000 -11.308
ENSG00000118515 E051 0.2352613 2.887019e-01 1.000000e+00   6 134187060 134187234 175 - 0.075 0.000 -10.060
ENSG00000118515 E052 0.8509302 9.961037e-02 6.325061e-02 0.2530040005 6 134187235 134187335 101 - 0.139 0.463 2.339
ENSG00000118515 E053 0.0000000       6 134188219 134188462 244 -      
ENSG00000118515 E054 0.2346346 1.564981e-02 1.000000e+00   6 134207356 134207431 76 - 0.075 0.000 -11.035
ENSG00000118515 E055 0.0000000       6 134214945 134214953 9 -      
ENSG00000118515 E056 0.0000000       6 134214954 134215093 140 -      
ENSG00000118515 E057 0.2340080 2.795004e-01 1.000000e+00   6 134218681 134218772 92 - 0.075 0.000 -10.070
ENSG00000118515 E058 0.4876513 8.788875e-02 7.488659e-02   6 134230400 134230481 82 - 0.075 0.356 2.753
ENSG00000118515 E059 0.1170040 1.171963e-02 5.897990e-01   6 134249456 134249540 85 - 0.039 0.000 -10.123
ENSG00000118515 E060 0.0000000       6 134259793 134261932 2140 -      
ENSG00000118515 E061 0.0000000       6 134261933 134262037 105 -      
ENSG00000118515 E062 0.0000000       6 134262038 134262148 111 -      
ENSG00000118515 E063 0.0000000       6 134317392 134317542 151 -      
ENSG00000118515 E064 0.0000000       6 134317543 134317814 272 -      
ENSG00000118515 E065 0.0000000       6 134317815 134318112 298 -      

Help

Please Click HERE to learn more details about the results from DEXseq.